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Human and Environmental Factors Shape Tree Species Assemblages in West African Tropical Forests

Aim: This study investigated how human activities and local environmental variables shape tree assemblages (species composition in a defined location), comparing their effects on edible and inedible tree species. Three hypotheses were tested: (1) Environmental filtering impacts spatial beta-diversity more than dispersal limitation; (2) human activities significantly influence regional tree beta-di

Neurobehavioral Outcomes at 10 Years of Age following Delayed Umbilical Cord Clamping : A Follow-Up Study after a Randomized Trial

INTRODUCTION: The aim of this study was to explore long-term behavioral consequences of early versus delayed cord clamping (CC) in school-aged children. The hypothesis was that early CC would be associated with an increased risk of symptoms associated with attention deficit hyperactivity disorder (ADHD) due to the lower iron stores following early CC compared with delayed CC.METHODS: Exploratory,

Fine-Grained Classification of Unpigmented Skin Cancer from Paired Dermatoscopy Images

Unpigmented skin cancer is the most prevalent form of cancer, and it burdens healthcare substantially even if it is not as aggressive as the more well-known malignant melanoma. Dermatoscopy images are commonly used for diagnosis, but differentiating between the many sub-diagnoses is a hard task. In this study we focus on these unpigmented cancers, performing both detection of basal cell carcinoma

Adherence to the EAT-Lancet diet, plasma proteomics and the risk of chronic obstructive pulmonary disease

BACKGROUND AND AIMS: Adhering to the EAT-Lancet diet has been observed to be associated with lower risks of various morbidities. This study aimed to investigate the association of adhering to the EAT-Lancet diet with incident chronic obstructive pulmonary disease (COPD) and identify plasma proteins mediating such association.METHODS: This prospective study involved 202 340 participants free of COP

Conversion between NMSS and MDS-NMS in Parkinson's Disease

Background: The burden of non-motor symptoms in Parkinson's disease (PD) can be measured with the Non-Motor Symptoms Scale (NMSS) and the International Parkinson and Movement Disorder Society Non-Motor Rating Scale (MDS-NMS), for which scoring systems, structure and clinical coverage differ. Objectives: The goal was to develop conversion formulas between the NMSS and the MDS-NMS scores. Methods: D

Cryo-EM structure of the human monocarboxylate transporter 10

The monocarboxylate transporter (MCT) membrane protein family has 14 human members that perform key cellular functions, such as regulating metabolism. MCT8 and MCT10 have unique cargo specificity, transporting thyroid hormone and, in the case of MCT10, aromatic amino acids. Dysfunctional MCT8 causes the severe Allan-Herndon-Dudley syndrome, yet the (patho)physiology and function of MCT8 and MCT10

Rethinking TNM : Tumor deposit-based prognostic models may improve N-staging in colorectal cancer

Introduction: Tumor deposits are an important negative prognostic factor for long-term oncological outcomes in colorectal cancer patients, independent of lymph node status. Several novel models have been proposed to further integrate tumor deposits into the TNM-staging system, but their comparative performance remains unclear. The aim of this study was to identify, compare and validate novel progn

Stuck in a neither/nor. : The impact of over-indebtedness on young people’s entry into adulthood

Based on in-depth interviews with young people experiencing over-indebtedness in Sweden, the paper illustrates the social consequences of over-indebtedness among young adults, particularly in terms of how debt problems affect the entry into adulthood. Combining theories of the indebted subject, social exclusion, emerging adulthood and liminality, the analysis shows that over-indebted young subjectBased on in-depth interviews with young people experiencing over-indebtedness in Sweden, the paper illustrates the social consequences of over-indebtedness among young adults, particularly in terms of how debt problems affect the entry into adulthood. Combining theories of the indebted subject, social exclusion, emerging adulthood and liminality, the analysis shows that over-indebted young subject

Traffic safety footprint and safe organisations

A core principle of the Safe System approach is shared responsibility among stakeholders and road users. Traditionally, public actors have shouldered most of the stakeholder responsibility, and traffic safety has mainly been viewed as a duty of governments [1,2]. However, the United Nations and the World Health Organisation call on all stakeholders, both public and private, to take on the responsi

Introduction

Traffic accidents pose a significant global challenge, causing nearly 1.2 million fatalities annually (WHO 2023). This alarming statistic places traffic accidents among the leading causes of death worldwide. In most countries, the police are responsible for compiling official accident statistics. They collect data at the scene of the accident, including details about the vehicles involved, the cir

Use of personal data and artificial intelligence-ethical and legal issues

As indicated in several earlier chapters in this anthology, traffic safety data are of many different types and studied in a large number of different activities. Many professional studies make use of already existing data, such as accident data records from police, insurance companies and hospitals, as well as statistical data derived from such databases. Other data are collected for specific pur

Long-term real-world outcomes of first-line immunotherapy in non-small cell lung cancer – a population-based cohort study in Sweden

Background: In a previous study, we explored real-world programmed death-ligand 1 (PD-L1) testing and treatment patterns for patients with advanced non-small cell lung cancer (NSCLC) in the era of immune-oncology. The present study aimed to investigate overall survival (OS) with PD-(L)1 inhibitors with longer-term follow-up in the Swedish setting. Materials and methods: Data were extracted from th

Comorbidity and Mortality in Men and Women With Haemophilia in Three Nordic Countries–Comparisons to Matched Controls

Introduction: Comorbidities and public health conditions in haemophilia are receiving increasing attention. Aim: To analyse the prevalence of comorbidities and mortality in people with haemophilia (PwH) compared to matched controls in subgroups (factor consumption and sex). Methods: This study used longitudinal individual-level data (11 years) from national registers in three Nordic countries (Den

Assessing reliable change, MCID, treatment response, and remission using the Pediatric Anxiety Rating Scale (PARS) in youth with anxiety disorders

Youth anxiety disorders are common and heterogeneous. The Pediatric Anxiety Rating Scale (PARS) is a clinician-administered tool designed to assess overall anxiety severity, independent of specific symptoms. The thresholds on PARS for the reliable change index (RCI), the minimal clinically important difference (MCID), treatment response, and full and partial remission remain unclear. Using the Cli