BACKGROUND: Streptococcus pneumoniae remains a major cause of community-acquired pneumonia, meningitis, and other diseases, contributing significantly to high morbidity and mortality worldwide. Although it responds to antibiotics, their use is becoming limited due to the rise in antibiotic resistance, which necessitates the development of new therapeutics. Nanotechnology is used to counteract anti

Background: Malignant Mesothelioma (MM), an orphan but aggressive malignancy of the mesothelial membrane, is a fatal tumor. Global epidemic related to malignant pleural mesothelioma is on the rise, so there is a need to explore novel biomarkers and ingenious therapeutic approaches to stalk this silent killer.Objective: The main aim of the present review is to provide a consolidated overview of the

Background: Rich in different kind of potent cells, embryos are used in modern regenerative medicine and research. Neurobiologists today are pushing the boundaries for what can be done with embryos existing in the transitory margins of medicine. Therefore, there is a growing need to develop conceptual frameworks for interpreting the trans‐ formative cultural, biological and technical processes inv

An interior building-archaeological investigation of parts of Glimmingehus castle has been conducted. One of the aims was to document the two large rooms, today called “the Banqueting Hall” and “the Archers’ Loft”. Another was to answer some questions about the original functions of the rooms. The two rooms are connected by a simple wooden staircase. One of the questions concerned the original loo

The present study suggests that the theoretical framework of evolutionary psychology, in particular theories and models relating to social status and pride, can be used to further our understanding of educational motivation. Our assumption was that the desire for social recognition and high status is a universal human phenomenon. Based on this, we suggested that differences in educational motivati

Water contamination with per- and polyfluoroalkyl substances (PFAS) is a serious problem for water suppliers in many regions. Due to persistence of the substances and a complex distribution mechanism, PFAS can have an adverse impact on water quality. Reported toxicological and health effects, make it very important to minimise the of wildlife and human exposure to PFAS. The exposure path is, howev

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Knowledge, when used effectively, is a major input for development. However, the processes associated with knowledge production, knowledge transfer, and knowledge use are complex and not easy to facilitate in certain parts of the world. This is mainly due to a lack of or limited interactions between knowledge producers and knowledge users. This thesis aims to explore how efforts to foster knowledg

Several pharmacogenetics studies have identified an association between a greater metformin-dependent reduction in HbA1c levels and the minor A allele at rs2289669 in intron 10 of SLC47A1, encoding multidrug and toxin extrusion 1 (MATE1), a presumed metformin transporter. It is currently unknown if the rs2289669 locus is a cis-eQTL, which would validate its role as predictor of metformin efficacy.

The challenges of sustainable development require whole supply chains and networks to drive change and innovation. However, most existing research on sustainable innovations is on a company level and the dominating company focus in practice drives “silo” approaches, short-term thinking, and profit maximization. Consequently, there is a need for research and new models that facilitate sustainable sThe challenges of sustainable development require whole supply chains and networks to drive change and innovation. However, most existing research on sustainable innovations is on a company level and the dominating company focus in practice drives “silo” approaches, short-term thinking, and profit maximization. Consequently, there is a need for research and new models that facilitate sustainable s

The use of radio signal for position tracking (positioning) and navigation has a long tradition. Most notably, global navigation satellite systems (GNSS) are now widely applied for civilian applications, ranging all the way from tracking of cargo containers to gaming. However, GNSS suffers from limited coverage in dense urban areas and indoors and also from a limited position accuracy, which rules

Production of a protein of interest in bacteria and its purification from bacterial lysates are valuable tools for the purification of larger amounts of recombinant proteins. The low cost of culturing, and the rapid cell growth of bacteria make this host a good choice for protein production, but the folding and function of the purified protein might be altered due to the production of a eukaryotic

Information and communication technology (ICT) is ubiquitous in tourism and this changes not only tourists’ immediate behaviour, but also what tourism is. In this way, digitalisation is shifting perceptions of when tourism starts and ends, and how we can understand the term in principal ways. The aim of this working paper is to contribute to the debate about the consequences of today´s fast digita