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Cost-effectiveness of raloxifene in the UK: an economic evaluation based on the MORE study

Raloxifene treatment has been shown to reduce the risk of vertebral fractures and breast cancer in postmenopausal women. The long-term economic implications of treatment with raloxifene have not yet been investigated. The aim of this study was to assess the cost-effectiveness of treating postmenopausal women in the UK with raloxifene. A previously developed computer simulation model was used to es

Role of arachidonic acid metabolites in airway responses induced by trimellitic anhydride in actively sensitized guinea pigs

We studied the role of arachidonic acid metabolites, histamine, and 5-HT in airway responses to trimellitic anhydride (TMA) in actively sensitized guinea pigs. Sensitization was produced by two intradermal injections of free TMA (0.1 ml of 0.3% TMA in corn oil). After 21 to 28 days, guinea pigs were anesthetized and challenged with intratracheal instillation of 0.5% TMA conjugated to guinea pig se

"Absalons borg" i Sövde - en befäst anläggning från tidig medeltid

Artikeln diskuterar händelser i och omkring Sövde i samband med det "Skånska upproret" 1180-81. I Sövde fanns från 1100-talet och fram till reformationen fanns en befäst huvudgård tillhörande ärkesätet i Lund. Spåren efter denna anläggning kom att undersökas år 1911 av pastor loci Oscar Blomstergren under överinseende av Otto Rydbeck, docent i nordisk konstarkeologi, Lund.

Seasonal variation of phosphorus limitation of bacterial growth in a small lake

A series of bioassay experiments were performed from spring to autumn in a small dimictic lake (Deep Pond, Massachusetts) to examine the potential for bacterial growth limitation by organic carbon (glucose), inorganic nutrients (ammonium or phosphate), or both. The experiments demonstrated that phosphorus was the primary element limiting bacterial growth in Deep Pond during a large part of the sum

Glomerular apoptotic nucleosomes are central target structures for nephritogenic antibodies in human SLE nephritis

Antibodies to double-stranded (dsDNA) are associated with systemic lupus erythematosus (SLE) and directly involved in human lupus nephritis. Information about their glomerular target antigens is inconsistent, and whether availability of target antigens, antibody specificity or avidity are nephritogenic parameters, is not determined. In this study, we analyzed renal tissue from anti-dsDNA antibody-

Familjeterapi tillämplig även i somatiska vården. Studieöversikt över medicinskt orienterad familjeterapi

By observing and analyzing the influence of the therapist on the family as well as interactions between family members, the encounter with a family in a medical setting can serve to improve the health of its members, by improving their ability to use their own resources. This method of focusing on the interaction between individuals in a family or other systems has been a valuable addition to medi

Late magnetic resonance imaging related to neurobehavioral functioning after aneurysmal subarachnoid hemorrhage

Twenty patients who underwent early aneurysm surgery--that is, surgery within 72 hours after rupture--underwent further follow-up examination including magnetic resonance imaging (MRI) of the brain and a comprehensive neuropsychological assessment. Significant statistical correlation between tissue loss as seen on a late MRI scan and neurobehavioral deficits could not be established. Among 9 patie

Body memories and doing gender: Remembering the past and interpreting the present in order to change the future

Narrative is one method of tapping individual and collective memory where human experience is organized into temporally meaningful episodes and where a "point" is often made. In research projects that I have carried out about working life, "body stories" are often spontaneously related in making a "point." These stories exemplify "doing gender"-that is how gendered relations (that revolve around e

Identification of the sex pheromone of the currant shoot borer, Lampronia capitella

Under an artificial light: dark cycle, females of Lampronia capitella were observed calling, with extended terminal abdominal segments, during the first 2 hr of the photoperiod. Extracts of terminal abdominal segments from females elicited large electroantennographic responses from male antennae. Gas chromatography with electroantennographic detection revealed three active peaks. Based on comparis

Evolution of reproductive strategies in the sexually deceptive orchid Ophrys sphegodes: How does flower-specific variation of odor signals influence reproductive success?

The orchid Ophrys sphegodes Miller is pollinated by sexually excited males of the solitary bee Andrena nigroaenea, which are lured to the flowers by visual cues and volatile semiochemicals. In O. sphegodes, visits by pollinators are rare. Because of this low frequency of pollination, one would expect the evolution of strategies that increase the chance that males will visit more than one flower on

Autodetachment of the nsnp2 4P1/2 states in negative ions

The purpose of this work is to compute the autodetachment rates of the nsnp2 P-4(1/2) levels for Be-(2s2p2), Mg-(3s3p2) and Ca-(4s4p2) . Fano's configuration interaction model is implemented to compute the interaction between the discrete and continuum spaces of the wavefunction, which are determined using the multiconfiguration Hartree-Fock technique. Analysing the decay mechanism of the P-4(1/2)