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Operando high-temperature near-ambient pressure X-ray photoelectron spectroscopy and impedance spectroscopy study of Ni−Ce0.9Gd0.1O2−δ solid oxide fuel cell anode

In this study we present the results of operando high temperature near-ambient-pressure x-ray photoelectron spectroscopy (HT-NAP-XPS) measurements of a pulsed laser deposited thin film Ni−Ce0.9Gd0.1O2−δ model electrode. In our measurements, we have used the novel three electrode dual-chamber electrochemical cell developed in our previous work at different H2 pressures and at different electrochemi

Identification of APTX disease-causing mutation in two unrelated Jordanian families with cerebellar ataxia and sensitivity to DNA damaging agents

BACKGROUND: Ataxia with oculomotor apraxia type 1 (AOA1) is a rare autosomal recessive cerebellar ataxia, caused by mutations in the APTX gene. The disease is characterized by early-onset cerebellar ataxia, oculomotor apraxia and severe axonal polyneuropathy. The aim of this study was to detect the disease-causing variants in two unrelated consanguineous Jordanian families with cerebellar ataxia u

Optimizing Treatment in Undertreated Late-Stage Parkinsonism : A Pragmatic Randomized Trial

Background: Treatment of patients with late-stage parkinsonism is often sub-optimal. Objective: To test the effectiveness of recommendations by a movement disorder specialist with expertise in late-stage parkinsonism. Methods: Ninety-one patients with late-stage parkinsonism considered undertreated were included in apragmatic a pragmatic multi-center randomized-controlled trial with six-month foll

Towards a bridging concept for undesirable resilience in social-ecological systems

Non-technical summaryResilience is a cross-disciplinary concept that is relevant for understanding the sustainability of the social and environmental conditions in which we live. Most research normatively focuses on building or strengthening resilience, despite growing recognition of the importance of breaking the resilience of, and thus transforming, unsustainable social-ecological systems. Undes

Survival and prognostic factors after transplantation, resection and ablation in a national cohort of early hepatocellular carcinoma

Background: In patients with early hepatocellular cancer (HCC) and preserved liver function, the choice between transplantation, resection and ablation and which factors to consider is not obvious and guidelines differ. In this national cohort study, we aimed to compare posttreatment survival in patients fulfilling predefined criteria, and to analyse preoperative risk factors that could influence

GDNF and Parkinson's Disease : Where Next? A Summary from a Recent Workshop

The concept of repairing the brain with growth factors has been pursued for many years in a variety of neurodegenerative diseases including primarily Parkinson's disease (PD) using glial cell line-derived neurotrophic factor (GDNF). This neurotrophic factor was discovered in 1993 and shown to have selective effects on promoting survival and regeneration of certain populations of neurons including

Planetarium software in the classroom

Students often find astronomy and astrophysics to be most interesting and exciting, but the Universe is difficult to access using only one's eyes or simple equipment available at different educational settings. To open up the Universe and enhance learning astronomy and astrophysics different planetarium software can be used. In this article we discuss the usefulness of such simulation software and

Who Needs 3D When the Universe Is Flat?

An overlooked feature in astronomy education is the need for students to learn to extrapolate three-dimensionality and the challenges that this may involve. Discerning critical features in the night sky that are embedded in dimensionality is a long-term learning process. Several articles have addressed the usefulness of three-dimensional (3D) simulations in astronomy education, but they have neith

Contrasting population trends of common starlings (Sturnus vulgaris) across Europe

The greatest loss of biodiversity in the EU has occurred on agricultural land. The Common Starling (Sturnus vulgaris) is one of the many numerous and widespread European farmland breeding bird species showing major population declines linked to European agricultural intensification. Here we present results based on monitoring data collected since 1975 in 24 countries to examine the influence of ch

Ceq Wong vocabulary

The vocabulary contains 947 meaning-word pairs ("entries") corresponding to core LWT meanings from the recipient language Ceq Wong. The corresponding text chapter was published in the book Loanwords in the World's Languages. The language page Ceq Wong contains a list of all loanwords arranged by donor languoid.

Of pipe dreams and fossil fools : Advancing Canadian fossil fuel hegemony through the Trans Mountain pipeline

This article uses the Trans Mountain pipeline expansion project as a Canadian case study to critically examine and showcase one instance of the hegemony of fossil fuels in the era of global heating. The present Canadian federal government, under the leadership of Liberal Prime Minister Justin Trudeau, is seeking to simultaneously position itself as a global climate leader while supporting the expl

A novel biomarker of MMP-cleaved prolargin is elevated in patients with psoriatic arthritis

Psoriatic arthritis (PsA) is a chronic musculoskeletal inflammatory disease found in up to 30% of psoriasis patients. Prolargin—an extracellular matrix (ECM) protein present in cartilage and tendon—has been previously shown elevated in serum of patients with psoriasis. ECM protein fragments can reflect tissue turnover and pathological changes; thus, this study aimed to develop, validate and charac

Human Rights, Culture and the Rule of Law

This new book examines the relationship between culture and respect for human rights. It departs from the oft-made assumption that culture is closely linked to ideas about community. Instead, it reveals culture as a quality possessed by the individual with a serious impact on her ability to enjoy the rights and freedoms as recognised in international human rights law in meaningful and effective wa

A seventeenth-century Mycobacterium tuberculosis genome supports a Neolithic emergence of the Mycobacterium tuberculosis complex

BACKGROUND: Although tuberculosis accounts for the highest mortality from a bacterial infection on a global scale, questions persist regarding its origin. One hypothesis based on modern Mycobacterium tuberculosis complex (MTBC) genomes suggests their most recent common ancestor followed human migrations out of Africa approximately 70,000 years before present. However, studies using ancient genomes

The Impact of Cultural Diversity on International Criminal Proceedings

This article analyses the impact of cultural diversity on international criminal proceedings, and what may be done to counter the unfortunate conditions — limited (or lack of) understanding, alienation and disagreement — resulting from this diversity. Each of these conditions, if ignored, seriously undermines not merely the efficacy of international criminal tribunals, but also their worth from th

Where does the elephant come from? The evolution of causal cognition is the key

Osiurak and Reynaud do not explain the evolutionary emergence and development of the elephant in the room, that is, technical cognition. We first argue that there is a tight correlation between the evolution of cumulative technological culture (CTC) and the evolution of reasoning about abstract forces. Second, intentional teaching plays a greater role in CTC evolution than acknowledged in the targ

Physical activity on prescription in routine health care : 1-year follow-up of patients with and without counsellor support

The effectiveness of counsellor support in addition to physical activity on prescription (PAP) from health care professionals has rarely been evaluated. This observational follow-up study investigated differences in physical activity levels and health-related quality of life (HRQoL) one year after PAP regarding patients’ use of counsellor support in addition to PAP in routine care. The study was c