We have recently described the immunosuppressive properties of AR-C117977 and AR-C122982, representatives of a group of compounds identified as inhibitors of lactate transporters (monocarboxylate transporters; MCTs). These compounds demonstrate the potential therapeutic usefulness of inhibiting MCT-1, but their physical and metabolic properties made them unsuitable for further development. We have

Popular Abstract in Swedish Avhandlingen innehåller tre empiriska studier som analyserar hur livsmedelsmarknaden påverkas av åtgärder för att fördjupa den europeiska ekonomiska integrationen. Fokus är på det svenska EU-medlemskap och det kontinuerliga arbetet med att harmonisera livsmedelslagstiftningen. Det senare har stor relevans för livsmedelsmarknaden eftersom det har funnits och fortfarande This thesis consists of three papers, all of which deal with the effects of deepening European integration on the food and beverage industry and market. The focus is on the period after Swedish EU membership in 1995. The last two papers use firm data and focus on the Swedish food and beverage industry, an industry which is an interesting case study as it was considered to be protected from foreign

BackgroundThe presence of orthostatic hypotension (OH) predicts all-cause mortality and incident cardiovascular disease. Whether or not OH is associated with the development of heart failure (HF) remains unknown.MethodsIn this Swedish population-based prospective study (the Malmö Preventive Project), the incidence of HF in relation to baseline OH, defined as decrease in systolic (SBP) >/=20 mm Hg

A resolution model for evolutionary conflicts of interest is proposed. We assume that two conflicting parties originally have different evolutionarily stable strategies (ESS) with respect to a continuous variable, but that only one value of the variable is simultaneously possible. Individuals from the two parties meet in antagonistic encounters. The side that invests more in the antagonistic behav

Angiosarcoma is a rare complication of breast cancer treatment. In order to define predictors, clinical presentation, and outcome, we characterized a population-based 50-year cohort of angiosarcomas after breast cancer. Clinical data were collected from all females with previous breast cancer who developed angiosarcomas/lymphangiosarcomas on the thoracic wall/upper extremity between 1958 and 2008

Popular Abstract in Swedish Hantering av avlopp och avfall är en del av alla människors vardag. Vår hälsa och miljö påverkas av metoderna vi tillämpar för att ta hand om rester från hushåll och industrier. Genom teknikens utveckling används idag bakterier i vattenreningsverk där avloppsvatten renas från alla skadliga föremål och föreningar. Med hjälp av matematiska uttryck och analyser, i samspel Biofilms are compact, sessile microbial communities that attach to surfaces in aqueous environments. In wastewater treatment, they are especially important for removal of phosphorus and nitrogen, which, if released into a receiving water body, can cause severe eutrophication. Mathematical models of biofilms in wastewater are used to understand the underlying processes and to describe and analyze b

I uppsatsen jämförs nio olika aktionsartsmodeller och föreslås därefter en modell för svenskans aktionsarter. Modellen kopplas till språkliga kriterier och testas mot ett autentiskt material. Uppsatsen ger en grundlig genomgång av internationella och inhemska aspekt- och aktionsartsmodeller samt diskuterar en rad av ämnets teoretiska kärnfrågor. Samtidigt ges en samlad genomgång av de språkliga da

Adjunctive treatment with hyperbaric oxygen therapy has recently been shown to improve ulcer healing in patients with chronic diabetic foot ulcer. The aim of the present study is to evaluate whether hyperbaric oxygen therapy improves the health related quality of life in these patients.

Having performed analytical validation studies, we are now assessing the clinical utility of the upgraded automated Bone Scan Index (BSI) in metastatic castration-resistant prostate cancer (mCRPC). In the present study, we retrospectively evaluated the discriminatory strength of the automated BSI in predicting overall survival (OS) in mCRPC patients being treated with enzalutamide.