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Efficacy and safety of outpatient treatment with direct oral anticoagulation in pulmonary embolism

Anticoagulant treatment of acute pulmonary embolism (PE) has traditionally been hospital-based. The lesser need for monitoring with the increasingly used direct acting oral anticoagulants (DOAC) in comparison to warfarin potentially facilitates outpatient treatment of PE with these drugs. This study aimed to evaluate efficacy and safety of outpatient treatment of PE with DOAC. We extracted data fr

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects

Bone mineral density (BMD) assessed by DXA is used to evaluate bone health. In children, total body (TB) measurements are commonly used; in older individuals, BMD at the lumbar spine (LS) and femoral neck (FN) is used to diagnose osteoporosis. To date, genetic variants in more than 60 loci have been identified as associated with BMD. To investigate the genetic determinants of TB-BMD variation alon

Current smoking is associated with a larger waist circumference and a more androgenic profile in young healthy women from high-risk breast cancer families

The purpose was to elucidate the interplay between current smoking, anthropometric measurements, and endogenous hormone levels in women ≤ 40 years. Questionnaires on lifestyle and reproductive factors were completed by 269 healthy women from high-risk breast cancer families between 1996 and 2006 in Sweden. Blood samples for analyses of plasma testosterone, estradiol, androstenedione, sex hormone-b

Does Female Leadership Matter? An Analysis of Swedish Foreign Ministers and their Parliamentary Speeches, 1955–2016

The current Swedish Foreign Minister, Margot Wallström, has in her foreign policy statement claimed that a feminist foreign policy will be an integral part of activities throughout the Swedish Foreign Service. Even though an explicit ‘feminist foreign policy’ is a rather recent and ‘Swedish’ phenomenon, foreign policies in line with such a general ‘feminist’ agenda may have been implemented throug

SNPs related to vitamin D and breast cancer risk : A case-control study

Background: It has been suggested that vitamin D might protect from breast cancer, although studies on levels of vitamin D in association with breast cancer have been inconsistent. Genome-wide association studies (GWASs) have identified several single-nucleotide polymorphisms (SNPs) to be associated with vitamin D. The aim of this study was to investigate such vitamin D-SNP associations in relatio

Predictors of multiglandular disease in primary hyperparathyroidism

Background: Primary hyperparathyroidism (pHPT) is caused by single- or multiglandular disease (MGD). Patients with MGD have an increased risk of complications at surgery and for persistence and recurrence after surgery. The study evaluated whether preoperative clinical and biochemical characteristics could predict MGD in patients with pHPT. Methods: We retrospectively evaluated patients operated 1

A 2-year follow-up study of patients with pharyngotonsillitis

Background: Longtime follow-up studies on patients with pharyngotonsillitis are rare. We aimed to describe the patterns of new visits for a sore throat, complications and tonsillectomy during 2 years in a cohort of patients with pharyngotonsillitis and non-infected controls. Methods: A retrospective chart review was performed on a cohort of patients with acute sore throat (n = 207), and non-infect

High risk of hypogonadism in young male cancer survivors

Objective: Cancer and its treatment in childhood and young adulthood can cause hypogonadism, leading to increased risk of long-term morbidity and mortality. The aim of this study was to evaluate the risk of presenting with biochemical signs of hypogonadism in testicular cancer survivors (TCS) and male childhood cancer survivors (CCS) in relation to the type of treatment given. Design: Case-control

Sustained Psoriasis Area and Severity Index, Dermatology Life Quality Index and EuroQol-5D response of biological treatment in psoriasis : 10 years of real-world data in the Swedish National Psoriasis Register

Background: Few studies have analysed the long-term effects of biological treatment in psoriasis. PsoReg, the Swedish national register for systemic psoriasis treatment, started in 2006 and now includes 10 years of real-world data on the effectiveness of biological treatment. Objectives: To analyse the long-term real-world outcome data of patients who are biologically naïve with moderate-to-severe

From Copperplate to Color Lithography : On the Modernization of an Illustrated Flora 1800-1900

År 1900 blev botanisten Carl Lindman ansvarig för återutgivningen av en hundra år gammal illustrerad flora, J. W. Palmstruchs Svensk botanik (1802–43). De gamla handkolorerade kopparsticken undersöktes noggrant, korrigerades och försågs med nya förstorade detaljer och trycktes sedan med färglitografi. I denna artikel studeras, ur ett bokhistoriskt perspektiv, hur den nya formen påverkar innehålletIn 1900 the Swedish botanist Carl Lindman was assigned responsibility for the republication of a one-hundred-year old illustrated flora, J. W. Palmstruch’s Svensk botanik (1802–43). The old hand-colored copperplates were meticulously examined, corrected, and supplied with new magnified details and then printed in color lithographs. This article closely examines, from a book historical perspective,

Introduction : “Formulas of Betrayal”—Traitors, Collaborators and Deserters in Contemporary European Politics of Memory

Basing their study on conceptualizations current in anthropology, history, memory studies, and cultural sociology, Eleonora Narvselius and Gelinada Grinchenko offer a new, complex approach to understanding the violations of loyalty and trust that constitute betrayal, as well as their present-day revisions. Acts of betrayal and their subsequent reinterpretations are viewed through the prism of powe

Demonized, domesticated, virtualized : fortification buildings as a case of Prussian heritage in present-day Kaliningrad

The article explores ways in which the nineteenth-century Prussian military architecture has been used and promoted as a part of the local heritage in the Russian exclave of Kaliningrad. Accommodation of the old fortification buildings to tourism and museum work has been publicly discussed since the beginning of the 2000s, but neither local nor federal authorities have proposed a plan to adapt the