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There are no established biomarkers to guide patient selection for neoadjuvant chemotherapy prior to radical cystectomy for muscle-invasive bladder cancer. Recent studies suggest that molecular subtype classification holds promise for predicting chemotherapy response and/or survival benefit in this setting. Here, we summarize and discuss the scientific literature examining transcriptomic or panel-

Atomic layer deposition (ALD) is an outstanding deposition technique to deposit highly conformal and uniform thin films with atomic precision. In particular, ALD of transition metal oxide layers from metal amido complexes and water finds its way in several technological fields, including green energy devices and in the semiconductor industry. These ALD reactions are believed to follow a reaction s

Aim: Sweden´s first multidisciplinary children's advocacy centre (CAC) was founded in 2005 as a collaborative practice between child protection services, the legal system and health care in response to police-reported child abuse. CACs were introduced in the county of Skåne in 2007. The aim of the study was to describe the health of children investigated at the CAC in Lund, and to examine whether

Sexual dimorphism is a ubiquitous source of within-species variation, yet the community-level consequences of sex differences remain poorly understood. Here, we analyse a bitrophic model of two competing resource species and a sexually reproducing consumer species. We show that consumer sex differences in resource acquisition can have striking consequences for consumer-resource coexistence, abunda

Cyclic chiral lactide is the monomer chemical for polymerization of high molecular weight polylactic acid (PLA). The synthesis of cyclic l-lactide starts from poly-condensation of l-lactic acid to a low molecular weight prepolymer and then depolymerized to cyclic l-lactide. Lignocellulose biomass is the most promising carbohydrate feedstock for lactic acid production, but the synthesis of cyclic l

People diagnosed with Parkinson's disease (PD) can experience significant neuropsychiatric symptoms, including cognitive impairment and dementia, the neuroanatomical substrates of which are not fully characterised. Symptoms associated with cognitive impairment and dementia in PD may relate to direct structural changes to the corpus callosum via primary white matter pathology or as a secondary outc

This contribution examines the evolution of public support for the euro since its introduction as a virtual currency in 1999, using a unique set of data not available for any other currency. We focus on the role of economic factors in determining the popularity of the euro. We find that a majority of citizens support the euro in each individual member country of the euro area (EA). The economic cr

Sweden and Malmö are widely considered forerunners of climate change mitigation and adaptation, both internationally and by self-proclamation. Political will, available resources, and public knowledge are fairly high. National and local policies and regulations are in place, and a dominant majority of Swedes is well informed about climate change and the associated obligations, seeing climate chang

The data collected in this dataset are narratives exploring public policies, attitudes, individual behaviors, and the collective experiences of the involved communities regarding vaccination during the COVID-19 pandemic. The narratives were written by the members of the interdisciplinary research network Navigating Knowledge Landscapes (NKL; http://knowledge-landscapes.hiim.hr/). The members of th

In order to satisfy the growing energy needs of our planet’s population, and at the same time mitigate global warming, sustainable energy sources such as solar energy are indispensable. In addition to conventional silicon-based solar cells, nanotechnology offers interesting approaches for complementary applications. Multi-junction solar cells based on III–V semiconductors hold today’s world-record

The objective of this article is to study the links between the financing of primary education, schooling and economic growth in France in the nineteenth century. To do so, we use information on the financing allocated by the State, the departments, the municipalities, and households over the period 1820–1913. Our analysis is in two stages. First, we analyse the evolution of these different types

Gasoline and methanol are highly recommended for low temperature combustion (LTC) engines due to their high research octane number. However, engines fuelled with these fuels suffer from high unburned hydrocarbon (UHC) and carbon monoxide (CO) emissions at low loads, which can be improved by controlling the level of mixture stratification. This paper reports on the experimental and numerical compar

Background: The signal transducer and activator of transcription 3 (STAT3) is involved in the progression of different tumors including prostate cancer (PCa). The expression of STAT3 in benign and malignant epithelium has been described previously but it has not been described in the stromal compartment. The aim of the present study was to evaluate the nuclear expression and prognostic value of di

Obsessive-compulsive disorder (OCD) is a treatable condition that often requires specialist care, particularly when comorbid with autism spectrum disorder (ASD). However, specialist clinics are few and typically located in large medical centers. To increase availability of evidence-based treatment for OCD in individuals with ASD, we adapted an internet-delivered cognitive behavior therapy (ICBT) p

In the paper, strategies for reduced order modeling of glass panels subjected to soft-body impact are developed by means of dynamic substructuring. The aim is to obtain accurate and computationally efficient models for prediction of the pre-failure elastic response. More specifically, a reduction basis for the subsystem representing the glass panel is established using correction modes, being fixe

Background: Instantaneous wave-free ratio (iFR) is a coronary physiology index used to assess the severity of coronary artery stenosis to guide revascularization. iFR has previously demonstrated noninferior short-term outcome compared to fractional flow reserve (FFR), but data on longer-term outcome have been lacking. Objectives: The purpose of this study was to investigate the prespecified 5-year