Enriched environment enhances recovery of motor function after focal ischemia in mice, and downregulates the transcription factor NGFI-A.
The purpose of this study was to investigate the effect of enriched environment on motor function after experimental stroke in mice, and to determine whether time in enriched environment affects functional recovery. Earlier investigations have shown that rats placed in an enriched environment after focal ischemia, remarkably improve motor function, but similar observations in mice have not been re