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. Streptococcus pyogenes is an important human pathogen responsible for substantial morbidity and mortality worldwide. Although . S. pyogenes is a strictly human pathogen with no other known animal reservoir, several murine infection models exist to explore different aspects of the bacterial pathogenesis. Inoculating mice with wild-type . S. pyogenes strains can result in the generation of new bac

In operating systems, resource managers are developed according to simplicity, low overhead, low memory footprint, extensibility and efficiency. Thread schedulers are designed and developed following these implementation-related guidelines. The performance of the implementation is then tested over a set of benchmarks. However, the ability to provide real-time guarantees of these policies is rarely

20 procent av patienterna som diagnostiseras med kolorektal cancer har metastaser vid diagnos och prognosen är bister, med en femårsöverlevnad på ca 10 procent. Kring 40–70 procent har därtill symtom av sin primärtumör vid diagnos. Kirurgi brukar reserveras för patienter med försämrad livskvalitet på grund av symtom som anemi och ileus eftersom kirurgi innebär risk för komplikationer och död. Pati

Many modern software applications have performance requirements, like mobile and embedded systems that must keep up with sensor data, or web services that must return results to users within an acceptable latency bound. For such applications, the goal is not to run as fast as possible, but to meet their performance requirements with minimal resource usage, the key resource in most systems being en

Kerma-area product (KAP) meters have a pronounced energy dependence when measuring air KAP for lightly filtered X-ray beams (RQR). Today, it is also common with more heavily filtered beams. In this work, the energy dependence for lightly as well as heavily filtered beams (RQC) was investigated for several KAP meter models. The relative energy dependence of the readings of an external and an intern

Complete data center failures may occur due to disastrous events such as earthquakes or fires. To attain robustness against such failures and reduce the probability of data loss, data must be replicated in another data center sufficiently geographically separated from the original data center. Implementing geo-replication is expensive as every data update operation in the original data center must

Background: By taking diet quality into account, we may clarify the relationship between genetically elevated triglycerides (TG) and low-density lipoprotein-cholesterol (LDL-C), and better understand the inconsistent results regarding genetically elevated high-density lipoprotein-cholesterol (HDL-C), and cardiovascular disease (CVD) risk. Methods: We included 24,799 participants (62 % women, age 4

In 2014, leadership studies saw the retraction of a number of journal articles written by prominent researchers who are closely associated with popular concepts such as transformational leadership, authentic leadership, ethical leadership and spiritual leadership. In response, The Leadership Quarterly published a lengthy editorial that presented these retractions as a sign of health in a mature sc

Sweden experienced a remarkable economic transformation between the 18th century and the outbreak of World War I. This dissertation consists of four self-contained papers that uses a quantitative empirical approach to identify key drivers of this transformation by analyzing the contribution of the potato to economic growth, the determinants of the early investments in mass schooling, and how the r

Apolipoprotein M (ApoM) plasma levels have been reported to be associated with risk of venous thromboembolism (VTE) recurrence. However, the role of genetic alterations in the ApoM gene in VTE recurrence remains unknown. The aim of this study was to identify genetic aberrations in ApoM gene in VTE recurrence and their role in prediction of VTE recurrence in a prospective follow-up study of 1465 VT

To achieve significant improvements, there is a need for a systematic approach in Road Safety Management. The first step of such approach is to define the burden of road casualties in the country. Part of defining the burden is the monetary valuation of the prevention of a fatality accident. Such “values of statistical life” are derived in a number of countries, however, there is a large variation

Detta åtgärdsprogram behandlar jordlöparen alvarlarvmördare (Calosomareticulatum). Alvarlarvmördarens världsutbredning går i ett bälte från Mellaneuropa bort till Kaukasien och arten återfinns idag endast på ett fåtal platser. En av dessa platser är Stora alvaret på Öland (Kalmar län). Alvarlarvmördarens förekomst på Stora alvaret, Öland, är inte enbart Sveriges enda förekomst utan en av Europas f

Collective identities of the Self (or Ego) vs. the Other are not only conveyed in and between cultures through verbal discourse but also through pictures. Such cultural constructions are often established and consolidated by storytelling, where, briefly put, events or situations are temporally ordered. Pictures and visual artworks may be powerful narrative resources for establishing and consolidat

To meet EU energy and climate targets, energy efficiency of the existing building stock must be drasticallyimproved. Within IEA ECB Annex 56 one of the best practice energy renovations is a group of multi-familybuildings in Sweden, recently thoroughly renovated. Residents' perception of renovations and appraisal ofimplemented measures were captured by interviews with tenants and a literature revie