Recent studies suggest that increased aldose reductase (AR) activity plays an important role in ischemia-reperfusion injury in the retina. The mechanisms are not completely understood, but may be linked to inflammation. In the present study, we investigated whether the AR inhibitor fidarestat suppressed the retinal inflammatory response induced by ischemia-reperfusion in a rat model. The inflammat

Fresh and frozen spores of the microsporidia Nosema apis and Nosema bombi were fixed using various fixatives at different times and temperatures. Paraformaldehyde and technical formaldehyde gave results comparable to or better than glutaraldehyde. Increased fixation temperature improved the fixation of spores from terrestrial hosts. Freezing did not destroy the cytology or the spore.

A steady state conjugate conduction-convection investigation is performed on vertical plate fin in which a small heat source is located. Heat from the fin surface is transferred to the surroundings by laminar natural convection. The governing equations for the problem are the heat conduction equation for the fin and the boundary layer equations, which are continuity, momentum and energy equations,

A short history of supportive therapy is delineated by the quadruple division in prehistory, definition, establishment and the phase of integration. Glimpses of the history of the development of the supportive concept are given. It is pointed out that the concept of supportive therapy is stemming from the awkward dichotomy from the ego-psychological paradigm in the psychoanalytic tradition: insigh

The sequence diversity of the entire mitochondrial control region (CR) of three meadow viper (Vipera ursinii) populations was analysed and compared to previously documented nuclear genetic variability at the major histocompatibility complex (MHC) Class I loci. One of the populations, a small and inbred Hungarian population, exhibited no MHC polymorphism, whereas the two other, sampled from large v

Objective: There is growing evidence in the neuropsychological literature that growth hormone (GH) deficiency is associated with cognitive impairment. There is also evidence that this impairment may be ameliorated with GH replacement therapy. The current study assessed the nature and severity of cognitive impairment associated with growth hormone deficiency, as well as effect of GH replacement on

We describe a simple combinatorial approximation algorithm for finding a shortest (simple) cycle in an undirected graph. For an undirected graph G of unknown girth k, our algorithm returns with high probability a cycle of length at most 2k for even k and 2k + 2 for odd k, in time O(n(3/2) root logn). Thus, in general, it yields a 2 2/3 approximation. We study also the problem of finding a simple c

This article presents a mechanical cutting force model for bandsawing. The model describes the variation in cutting force between individual teeth and relates it to initial positional errors, tool dynamics and edge wear. Bandsawing is a multi-tooth cutting process, and the terminology of the cutting action is discussed and compared with other cutting processes. It will also be shown that the setti

We tested two consequences of a currently influential theory based on the notion of seeing adaptations to climate change as local adjustments to deal with changing conditions within the constraints of the broader economic–social–political arrangements. The notion leaves no explicit role for the strength of personal beliefs in climate change and adaptive capacity. The consequences were: (i) adaptiv

Objective. Although partial meniscectomy is a risk factor for the development of knee osteoarthritis (OA), there is a lack of evidence that meniscal damage that is not treated with surgery would also lead to OA, suggesting that surgery itself may cause joint damage. Furthermore, meniscal damage is common. The aim of this study was to evaluate the association between meniscal damage in knees withou

This thesis deals with the hunting of wild boar during the Mesolithic in South Scandinavia and the relationship between humans and wild game. The study is based on an analysis of osteological remains from sites in Scania, Sweden, dating from the Late Maglemose Culture to the Early Ertebølle Culture. Tooth development and tooth wear in recent populations from Poland, Germany and Sweden have been s

We extend the algorithm for matching fixed-order tree-level matrix element generators with the Dipole Cascade Model in Ariadne to apply to processes with incoming hadrons. We test the algoritm on for the process W+n jets at the Tevatron, and find that the results are fairly insensitive to the cutoff used to regularize the soft and collinear divergencies in the tree-level matrix elements. We also i

Objective. To describe the prevalence, characteristics, attribution, and clinical significance of neuropsychiatric (NP) events in an international inception cohort of systemic lupus erythematosus (SLE) patients. Methods. The study was conducted by the Systemic Lupus International Collaborating Clinics (SLICC). Patients were enrolled within 15 months of fulfilling the American College of Rheumatolo

Two Late Jurassic successions from western Skåne were investigated with respect to clay mineral contents of mudstones. Although these resemble clay mineral suites from a third succession in Central Skåne, it is evident that different depositional areas show separate clay mineral trends with time, probably due to that detrital clay minerals were derived locally from heterogeneous weathered crystall

1H-[1,2,3]-Triazol-1-yl mannosides have been synthesized as inhibitors for the beta-galactoside-binding family of galectin proteins. Easier synthetic access to C1 in mannose, as compared to C3 in galactose, for attachment of affinity-enhancing triazoles rendered a synthetic advantage. The best mannose-derived inhibitor for galectin-9N, 4-benzylaminocarbonyl-1H-[1,2,3]-triazol-1-yl beta-D-mannopyra

A number of failures have recently occurred in glulam structures in the Scandinavian countries. This paper analyses and discusses two of these failures: Two recently built glulam roof structures with spans of about 75 and 55 m that failed under low loading conditions. Gross error in the design was found to be the main cause in one case, but other potential failure causes were identified and analys