The decision to begin eating or to stop eating is a complex process. Hunger is primarily driven by hunger signals, like ghrelin and neuropeptide Y, originating from the gastrointestinal tract and from the hypothalamus. The hunger signals stimulate the seeking of food and the eating, being activating for the body and mind. Thirty minutes after the start of eating, satiety signals arise from the int

Virtual machines raise the abstraction level of the execution environment at the cost of restricting the set of supported languages. Moreover, the ability of a language implementation to integrate with other languages hosted on the same virtual machine typically constrains the features of the language. In this paper, we present a highly flexible yet efficient approach to hosting multiple programmi

Isaac Levi has claimed that our reliance on the testimony of others, and on the testimony of the senses, commonly produces inconsistency in our set of full beliefs. This happens if what is reported is inconsistent with what we believe to be the case. Drawing on a conception of the role of beliefs in inquiry going back to Dewey, Levi has maintained that the inconsistent belief corpus is a state of

OBJECTIVE—The purpose of this study was to evaluate the metabolic effectiveness, safety, and tolerability of nateglinide in subjects with impaired glucose tolerance (IGT) and to identify a dose appropriate for use in a diabetes prevention study. RESEARCH DESIGN AND METHODS—This multicenter, double-blind, randomized, parallel-group, fixed-dose study of 8 weeks’ duration was performed in a total of

OBJECTIVE: To evaluate whether power Doppler predicts ovarian response to gonadotrophin stimulation during in vitro fertilization (IVF). METHODS: Forty-five women were divided into low-reserve (n = 12) and normal-reserve (n = 33) ovarian groups, according to antral follicle count. Transvaginal three-dimensional power Doppler ultrasonographic examinations were performed after pituitary downregulati

The peakons are peaked traveling wave solutions of an integrable shallow water equation. We present a variational proof of their stability.

The diffusion rate of a species, in a dense matrix of methane-producing microorganisms, was determined experimentally. To this end, a specially designed diaphragm diffusion cell was utilized. The experimental results revealed that the effective diffusion coefficient in a microorganism matrix was 22–33% of the diffusion coefficient in pure water.

OBJECTIVES: The objective was to analyse whether a favourable change in risk factors, caused by a comprehensive risk factor modification programme, affected intima-media thickness (IMT) in the common carotid artery, and whether any such change was associated with a change in cardiovascular events during a 6-year follow-up. DESIGN: Patients were randomized 1 : 1 to special intervention or usual car

This report presents the results of two \emph{Escherichia~coli} cultivations performed in a large scale industrial bioreactor. The experiments aimed at evaluating a probing feeding strategy that adresses the problem of acetate accumulation. The principle is to superimpose short pulses in the glucose feed and evaluate the response in the dissolved oxygen signal for the feed adjustments. Simulations

The article concerns selected important issues of poetics and its history. The authors analyze and interpret the history of the notion of the sublime. The article is an introduction to a theoretical part of a book about a possible theory of the literary work of art and communication that results from the experience of the sublime. The introductory article presents to the reader questions which are

Results from sorption measurements at 23 °C on Picea abies in the intervals 54 to 75% RH and 75 to 84% RH are reported. In the higher interval non-Fickian sorption is clearly seen.

The continuous growth of world population and its concentration in the urban areas require food supplies that are continuous, sufficient and of good quality. To resolve this problem techniques have been developed for increasing food quantity and quality. The techniques are applied throughout the food chain from production, conservation and during distribution to the consumers (from "the field to t

A review on the subject of aspirin resistance and its role in vascular diseases is presented. Although the clinical diagnosis of aspirin resistance is frequently made, little is known about its biochemical background. Only a few follow-up studies, with varying design, have dealt with the possible association between an aspirin resistant phenotype and clinical outcome in patients with atherothrombo

Background: Functional polymorphisms of the solute carrier family 22, member 4 (SLC22A4), runt related transcription factor 1 (RUNX1) and small ubiquitin- like modifier 4 (SUMO4) genes have been shown to be associated with several autoimmune diseases. Objective: To test the possible role of these variants in susceptibility to or severity of systemic lupus erythematosus (SLE), on the basis that com

5-(2'-oxoheptadecyl)-resorcinol (1) and 5-(2'-oxononadecyl)-resorcinol (2) were isolated from fermentations of an imperfect basidiomycete. The structures of the compounds were determined by spectroscopic techniques. Both compounds exhibit cytotoxic effects against the human colon tumor cell lines COLO-320, DLD-1 and HT-29 and the human promyeloid leukemia cell line HL-60, the human leukemia T cell

Objective: Explore how clinicians select drug treatment based on symptoms, side effects and patient factors, including patient participation in the process, and the association between these factors and attitudes towards drugs. Method: A cohort of 166 patients initially treated with risperidone was followed with yearly assessments over 5 years. At the end of the study, 101 patients were evaluated

Insulin induced phosphorylation and activation of the cGMP inhibited cAMP phosphodiesterase (cGI-PDE) in human platelets were demonstrated after isolation of the enzyme with specific polyclonal cGI-PDE antibodies. The demonstration of this insulin effect required suppression of basal cGI-PDE phosphorylation, through the use of the protein kinase inhibitor H-7 (1-(5-isoquinolinylsulfonyl)-2-methylp