Background: Real-world data on long-term outcomes of vedolizumab (VDZ) are scarce. Objective: To assess long-term outcomes (up to 3 years) of VDZ in treating inflammatory bowel disease (IBD). Design: A nationwide, prospective multicentre extension of a Swedish observational study on VDZ assessing Effectiveness And Healthcare resource utilization in patients with IBD (SVEAH). Methods: After re-cons

Tillgänglighet har blivit ett centralt begrepp i transportpolitiken. Begreppet har dock kommit att bli alltmer mångfacetterat och det förekommer en rad olika definitioner. Tillgänglighet anses bestå av tre olika delkomponenter: transportsystemet, markanvändningssystemet samt individen, där interaktionen mellan dessa tre delar anses väsentlig. Tillgång till informations- och kommunikationsteknik (I

Studiens syfte har varit att genom en litteratursammanställning ta reda på hur forskningsområdet har sett att Covid-19-pandemin kan bidra till varaktiga förändringar i resande och transporter. Flera trender etablerades eller förstärktes under pandemin, men det är svårt att med säkerhet avgöra om de kommer hålla i sig. Ett problem som vi har sett är att det finns för lite data för att utveckla nya

In Lexel (Case C-484/19), the Swedish interest deduction limitation rules were found to be in breach of article 49 of the TFEU on the freedom of establishment, as they presumed abusive practices even in respect of arm’s length-based transactions. The present article puts the case into context and highlights follow-up issues raised before lower Swedish tax courts in the context of loan transactions

PURPOSE: Hypertension is a major global health concern. Despite of efficient antihypertensive medications a low percentage of patients reach a blood pressure (BP) of

INTRODUCTION: We studied whether adding percent free prostate-specific antigen (%fPSA) to total PSA improves prediction of clinically significant prostate cancer (csPCa) and fatal PCa.METHODS: 6727 men within the intervention arm of the Prostate, Lung, Colorectal and Ovarian Trial had baseline %fPSA. Of this cohort, 475 had csPCa and 98 had fatal PCa. Cumulative incidence and Cox analyses were con

The brown seaweed Alaria esculenta is the second most cultivated species in Europe, and it is therefore of interest to expand its application by developing food products. In this study, a lactic acid bacteria consortium (LAB consortium) consisting of three Lactiplantibacillus plantarum strains (relative abundance ~94%) and a minor amount of a Levilactobacillus brevis strain (relative abundance ~6%

Introduction: Preeclampsia (PE) is a pregnancy-related disorder associated with maternal hypertension and placental dysfunction. A significant micronutrient during pregnancy is iron, which is important in cellular functions. While iron absorption increases in pregnancy, little is known about the exact mechanisms regulating maternal iron levels and transfer through the placenta in normal and compli

I will present the results of our investigation of the Gaia Phase Spiral using Gaia Data Release 3. The phase spiral is a pattern in the plane defined by the vertical velocity (VZ) and vertical distance from the Galactic plane (Z). We have been able to determine the phase spiral's orientation and strength, or amplitude, at different locations in the Galactic disc by using a model we developed for

Daily life with severe mental health (SMI) and cancer comorbidity entails multiple challenges. The study aims to explore everyday life experiences among individuals with SMI and cancer comorbidity from the perspectives of patients, significant others, and involved healthcare professionals. The study is registered in PROSPERO (CRD42021259604). A qualitative systematic review was conducted through s

Asylum-seekers, like any population, need healthcare services, yet national laws sometimes restrict access to such services. The European Social Charter (revised) protects the right to health and medical services. However, the Charter has a complex application, and its scope is limited concerning foreigners. This article analyses to what extent the provisions of the Charter on the right to health