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Epigenetic changes may contribute substantially to risks of diseases of aging. Previous studies reported seven methylation variable positions (MVPs) robustly associated with incident type 2 diabetes mellitus (T2DM). However, their causal roles in T2DM are unclear. In an incident T2DM case-cohort study nested within the populationbased European Prospective Investigation into Cancer and Nutrition (E
These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry enabling immunologists to avoid the common errors that often undermine immunological data. Notably, there are comprehensive sections of all major immune cell types with helpful Tables detailing phenotypes in mu
The global public health problem of intimate partner violence against women (IPVAW) is typically tied to gender inequality. Contrary to what would be expected, however, a 2012 survey conducted by the European Union Agency for Fundamental Rights (FRA) showed lifetime prevalence rates of IPVAW in the Nordic countries which were among the highest of the 28 EU member states, despite these countries be
Residential energy consumption is a consequence of household members’ activities in their homes. Analysing and understanding energy consumption in households therefore needs to start from household activities and everyday life. From household members’ time diaries, we can analyse and learn about when, where and what energy-related activities occur in the household, involving what household members
PURPOSE: The R2Pulm trial was conducted to evaluate the effect of busulfan-melphalan high-dose chemotherapy with autologous stem-cell rescue (BuMel) without whole-lung irradiation (WLI) on event-free survival (main end point) and overall survival, compared with standard chemotherapy with WLI in Ewing sarcoma (ES) presenting with pulmonary and/or pleural metastases. METHODS: From 2000 to 2015, we e
A review concerning road tunnel fire safety and risk is presented. In particular different perspectives and methodson safety and risk are discussed. Road tunnel fire safety usually involves high uncertainty and high-stakes decisions.Thus, a wider group of stakeholders and different types of knowledge should be included in the fire safety analysisand evaluation, than what is required by technical r
Objectives: Functional gastrointestinal (GI) symptoms, such as IBS (irritable bowel syndrome), have been suggested to be associated with autonomic neuropathy. We therefore examined associations between hemodynamic indices of autonomic control, functional GI symptoms and stress in a population-based cohort.Methods and materials: The study included 2094 participants of the Malmö Offspring Study (mea
Samhällsplaneringen har i någon månalltid varit intresserad av relationellaflöden. Det bilsamhälle som cementeradesunder efterkrigstidens rekordår var ihögsta grad en fråga om att styra rörelsermellan olika platser med industrins behovav arbetskraft som ledstjärna. Men, omvi ser närmare var det inte bara regionplanenstrafiksystem som var relationellt.Bostadsgården skulle skapa platser förolika anv
Mastering a new language (L2) implies the need to readjust the associations between different components (phonology, lexicon, grammar) in the native language (L1). L2 speakers have often been observed to apply prosodic patterns from their first language when processing a new language. Swedish speakers have been reported to produce a word melody that resembles accent 1 when speaking foreign languag
Investigates the accuracy of using fire Dynamics equations in tunnel fire Safety risk analysis
This article aims to contribute to discussions and reflections upon the practice and theory of fire safety design. Are we reaching the results we want by the best available means? The theoretical framework of fire safety design is today restricted by a linear design process where mainly quantitative data and methods matters. A deterministic approach to safety ignores the decision-making context an
