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Human brain tumor stem cells have been enriched using antibodies against the surface protein CD133. An antibody recognizing CD133 also served to isolate normal neural stem cells from fetal human brain, suggesting a possible lineage relationship between normal neural and brain tumor stem cells. Whether CD133-positive brain tumor stem cells can be derived from CD133-positive neural stem or progenito
In chlorophyll biosynthesis, insertion of Mg2+ into protoporphyrin IX is catalysed in an ATP-dependent reaction by a three-subunit (BchI, BchD and BchH) enzyme magnesium chelatase. In this work we present the three-dimensional structure of the ATP-binding subunit BchI. The structure has been solved by the multiple wavelength anomalous dispersion method and refined at 2.1 A resolution to the crysta
Popular Abstract in Swedish Eftersom politiska partier är kollektiva varor står potentiella partibildare inför det kollektiva handlandets problem. Därför kan vi tala om en "partibildningsparadox". Sålunda är det förvånande att icke riksdagsetablerade partier blev vanligare förekommande i svenska kommuner mellan 1973 och 2002. Utvecklingen ger oss ett unikt material på vilket vi kan pröva hypoteserSince political parties are collective goods, groups of people that demand new political parties face a collective action problem. Therefore, we can speak of a ?paradox of party-emergence?. Hence, it is puzzling that new parties became increasingly common in representative bodies at the Swedish local level during 1973?2002. This development provides a unique circumstance on which to test hypothese
Objective. To study residual tumours at second-look resection in patients resected 4-8 weeks earlier for T1 tumours of the urinary bladder. Material and methods. All patients randomized in the ongoing Nordic T1G2-G3 Bladder Sparing Study with monitored data available were included in the study. Data on residual tumours at second-look resection were compared to basic patient and tumour characterist
On-chip enzyme reactors are often used in medical/pharmaceutical analysis due to their inherent advantages, such as high sample throughput, low reagent consumption, stability, reproducibility and low cost. The present work describes a different application of such microreactors, namely, elimination of interfering ascorbate signals in glutamate monitoring using ascorbate oxidase modified silicon ch
Airborne dust samples from damp (n = 9) and control (n = 9) residences were analyzed for microorganisms (molds and bacteria), bacterial markers (3-hydroxy fatty acids and muramic acid), and adsorbed volatile organic compounds (VOCs). The number of mold species was greater in the damp residences than in the controls (23 vs.18) and nine mold species were found only in damp residences. The levels of
Protein C (PC), a 62 kDa multi-modular zymogen, is activated to an anticoagulant serine protease (activated PC or APC) by thrombin bound to thrombomodulin on the surface of endothelial cells. PC/APC interacts with many proteins and the characterisation of these interactions is not trivial. However, molecular modelling methods help to study these complex biological processes and provide basis for r
In 1986, Keil provided an O(n(2)) time algorithm for the problem of covering monotone orthogonal polygons with the minimum number of r-star-shaped orthogonal polygons. This was later improved to O(n) time and space by Gewali et al. in [L. Gewali, M. Keil, S.C. Ntafos, On covering orthogonal polygons with star-shaped polygons, Information Sciences 65 (1992) 45-63]. In this paper we simplify the lat
Using the Fourier Transform Spectrometer at Lund Observatory, intensity calibrated spectra of singly ionized zirconium have been recorded and analyzed. Oscillator strengths for 263 Zr II spectral lines in the region 2500-5400 angstrom have been derived by combining new experimental branching fractions with previously measured radiative lifetimes. The transitions combine 34 odd parity levels with 2
Abstract not available.
Objective: The aim in this study was to assess the association between individual plasma carotenoid levels (alpha-carotene, beta-carotene, lycopene, beta-cryptoxanthin, lutein, zeaxanthin) and fruit and vegetable intakes recorded by a calibrated food questionnaire (FQ) and 24- h dietary recall records (24HDR) in nine different European countries with diverse populations and widely varying intakes
The thesis deals with the determination of the post peak behaviour of concrete in pure tension, and combined tension (compression) and shear. A test arrangement has been developed in order to determine the post peak behaviour of concrete expressed as stress - displacement curves. The theoretical basis of the thesis is in accordance with the "Fictitious Crack Model" which is a model based on the s
I denna artikel diskuteras betydelsen av kroppen som en uppmärksam och aktiv aktör i rituell praktik, förankrad i en specifik social och historisk kontext, de kanadensiska mi’kmaqindianernas livsvärld. Mi’kmaqs möjlighet att arbeta om den kulturella kropp det dominerande samhället har implementerat i dem, öppnar nya vägar att göra sig av med destruktiva mönster som de medvetet eller omedvetet har
The effect of thermal ionization on the growth of soot particles has been analyzed by detailed kinetic modeling of a low-pressure premixed acetylene flame. The detailed kinetic model considers the oxidation of fuel, the formation and growth of polycyclic aromatic hydrocarbons, and particle inception, coagulation, as well as mass growth via surface reactions. A numerical method has been developed,
Objective. Ileal pouch anal anastomosis ( IPAA) is the preferred method for restorative surgery in patients with ulcerative colitis who have to undergo proctocolectomy. The most common complication is pouchitis and several studies have pointed to the microbiota of the pouch as being a risk factor. The aim of this study was to follow the development of the bacterial microbiota in pouches during the
