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The Ku autoantigen has been implicated in a number of cellular functions including growth control, immunoglobulin gene rearrangement and DNA repair. A variant truncated form of Ku86, with an apparent molecular weight of 70 kDa, has been reported to be present in many human cell types. We have previously shown that the amount of variant Ku86 is strongly increased in human peripheral blood mononucle
We present ab initio calculations of the optical rotation of S-propylene oxide in both gas phase and solution using the coupled cluster methodology combined with a dielectric continuum description of the solvent. The coupled cluster calculations are performed using the CCS, CC2, CCSD and CC3 methods. None of the presented gas phase results are in accord with the experimental sign of the optical ro
The article presents the third study of a series that has been designed to manifest consciousness and to measure developed competence. The emphasis of the main hypothesis has been put on the student’s ability to adapt to the main idea of a given story and to express his comprehension verbally. In what way the two students of the previous two experiments have been able to accomplish the experimenta
Gene expression analyses were performed on 121 consecutive childhood leukemias (87 B-lineage acute lymphoblastic leukemias (ALLs), 11 T-cell ALLs and 23 acute myeloid leukemias (AMLs)), investigated during an 8-year period at a single center. The supervised learning algorithm k-nearest neighbor was utilized to build gene expression predictors that could classify the ALLs/AMLs according to clinical
Målsättningen för projektet är att studera uppvärmningsenergibehov, energiförbrukning och inomhusklimat i 31 radhuslägenheter i Malmö med gasvärme. Detta görs genom att studera energibalansen för lägenheterna, funktionen hos systemen med luftburen värme, funktionen hos gasvärmesystemen samt de boendes upplevelse av inneklimatet via enkäter.
Analytical models to calculate notch development and subsequent mass failure of dunes are presented. The notch evolution model is based on a transport equation for sediment from the dune and the sediment volume conservation equation, whereas the models of mass failure are derived using elementary engineering statics and soil mechanics. An empirical transport coefficient in the model describing the
We present an algorithm for the inverse scattering problem associated to a nonlinear equation arising in the study of the unidirectional propagation of waves in shallow water.
Serine proteases play a central role in defense against pathogens by regulating processes such as blood clotting, melanization of injured surfaces, and proteolytic activation of signaling pathways involved in innate immunity. Here, we present the functional characterization of the Drosophila serine protease Sp7 (CG3006) by inducible RNA interference. We show that Sp7 is constitutively expressed in
Autoignition with SI compression ratio can be achieved by retaining hot residuals, replacing some of the fresh charge. In this experimental work it is achieved by running with a negative valve overlap (NVO) trapping hot residuals. The experimental engine is equipped with a pneumatic valve train making it possible to change valve lift, phasing and duration, as well as running with valve deactivatio
Boken handlar om jag-begreppet i tanke och tal. Huvudfrågan är vad vi menar när vi säger 'jag. Relaterade frågor rör vilka sorters jag-kunskap och självmedvetande som behövs för att kunna tala om sig själv. Betoningen ligger på menings- och referensteorier, men ett stort utrymme ägnas även åt jag-tankar och jagbegreppets roll för tänkande i allmänhet.The subjct of this book is the first person in thought and language. The main question is what we mean when we say 'I'. Related to it are questions about what kinds of self-consciousness and self-knowledge are needed in order for us to have the capacity to talk about ourselves. The emphasis is on theories of meaning and reference for 'I', but a fair amount of space is devoted to 'I'-thoughts and t
We report EHT calculations of the band electronic structure of substituted pentacene derivatives and the polymorphs of the parent compound. The results show that there are wide disparities among the bandwidths and electronic dimensionalities of these compounds. The parent pentacene polymorphs are 2-dimensional in their band electronic structure with moderate dispersions; the bandwidths in the 14.1
Results from quantum chemical INDO/S-CI calculations of the absorption properties of anatase TiO2 nanoparticles sensitized by catechol and benzoic acid are reported. Experimental observations that catechol causes a strong shift in the TiO2 absorption threshold, while benzoic acid does not, are explained from the calculations which indicate that only catechol introduces electronic levels in the TiO
The use of reconfigurable matching has become more and more desirable as mismatches between such interfaces as antenna and receiver increase. The present paper investigates reconfigurable matching by measurements of a CMOS Impedance Tuning Unit (ITU) designed for Digital Video Broadcasting for Handheld devices (DVB-H). The ITU consists of switched capacitors arranged in three capacitor banks, with
OBJECTIVES: Our goal in this study was to explore the use of a hybrid approach to calculate benchmark doses (BMDs) and their 95% lower confidence bounds (BMDLs) for renal effects of cadmium in a population with low environmental exposure. METHODS: Morning urine and blood samples were collected from 820 Swedish women 53-64 years of age. We measured urinary cadmium (U-Cd) and tubular effect markers
