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Cartilage oligomeric matrix protein forms protein complexes with synovial lubricin via non-covalent and covalent interactions

Objective: Understanding the cartilage surface structure, lost in arthritic disease, is essential for developing strategies to effectively restore it. Given that adherence of the lubricating protein, lubricin, to the cartilage surface is critical for boundary lubrication, an interaction with cartilage oligomeric matrix protein (COMP) was investigated. COMP, an abundant cartilage protein, is known

Modeling of the SLIPI technique with the large scatterer approximation of the RTE

To overcome the blur when visualizing of the interior of a turbid media by means light-based methods, a technique called Structured Laser Illumination Planar Imaging (SLIPI) is employed. The method is based on a 'light coding' strategy to distinguish between directly and multiply scattered light, allowing the intensity from the latter to be suppressed by post-processing data. In this paper, we exp

Optimised treatment of hip fractures

Fractures of the proximal part of the femur, hip fractures, are common and costly. The number of hip fractures has increased in all western countries during recent decades. This has occurred mainly because of an increase in the number of elderly people and also due to an increase in the risk for hip fracture among the oldest persons. Due to an increase in ageing population all over the world there

Cancer risk in patients with hepatitis C virus infection : A population-based study in Sweden

Increased risks of certain cancers have been observed in patients with hepatitis C virus (HCV) infection. However, data on other cancer sites/types are lacking. We analyzed systematically the risk of developing 35 common cancers in patients with HCV infection using a nationwide Swedish database. Patients with HCV infection were identified from the Swedish Hospital Inpatient and Outpatient Register