Background: Most patients with Parkinson's disease, Parkinson's disease dementia, and dementia with Lewy bodies do not carry mutations in known disease-causing genes. The aim of this study was to identify a novel gene implicated in the development of these disorders. Methods: Our study was done in three stages. First, we did genome-wide linkage analysis of an Italian family with dominantly inherit

To understand the dynamics of ecosystem carbon cycling more than 10 years of eddy covariance data, measured over an evergreen, temperate, wet sclerophyll forest, were analysed and related to climate drivers on time scales ranging from hours to years. On hourly timescales we find that incoming shortwave radiation is the major meteorological driver of net ecosystem carbon exchange (NEE). Light use e

Terrestrial laser scanning (TLS) with the Echidna Validation Instrument (EVI) provides an effective and accurate method for calibrating multiple-return airborne laser scanning (ALS) point cloud distributions to map effective leaf area index (LAIe) and foliage profile within a 1-km diameter test site of mature eucalyptus forest at the Tumbarumba research site, New South Wales, Australia. Plot-based

Satellite based remote sensing provides an efficient way to estimate carbon balance components over large spatial domains with acceptable temporal and spatial resolution. In the present study remote sensing based gross primary production (GPP) estimations were evaluated using data from a tall eddy-covariance flux tower, located over a heterogeneous agricultural landscape in Hungary. Four different

A major challenge in evolutionary biology consists of understanding how genetic and phenotypic variation is created and maintained. In this study, we investigated the origin(s) and evolutionary patterns of the female-limited colour polymorphism in ischnuran damselflies. These consist of the presence of one to three colour morphs: one androchrome morph with a coloration that is similar to the male

Som ett led i vår egen fortbildning inom blended learning (blandade lärmiljöer), har vi valt att utveckla nya digitala verktyg inom en kurs som heter ”Introduktions- kurs i service management” (15 högskolepoäng, cirka 300 studenter). Målet med att införa nya digitala verktygen är att underlätta för studenterna att skapa förståelse för kurslitteraturen (teorier, begrepp och modeller) på kursens för

En artikel om den "Mediko-teologiska fakulteten" vid Lunds universitet och den pastoralmedicinska utbildningen (en propedeutisk kurs i medicin för landsbygdspräster) 1811-1841.

Objective To investigate the association between alcohol consumption (at baseline and over lifetime) and non-fatal and fatal coronary heart disease (CHD) and stroke. Design Multicentre case-cohort study. Setting A study of cardiovascular disease (CVD) determinants within the European Prospective Investigation into Cancer and nutrition cohort (EPIC-CVD) from eight European countries. Participants 3

Allogeneic hematopoietic stem cell transplantation (HSCT) is beneficial for pediatric patients with relapsed or (very) high-risk acute lymphoblastic leukemia (ALL) in remission. A total of 1115 consecutive patients were included in the ALL SCT 2003 BFM study and the ALL SCT 2007 I-BFM study and were stratified according to relapse risk (standard versus high versus very high risk of relapse) and do

For years, a popular explanation for women choosing to abandon studies in science, technology, engineering, and mathematics (STEM) has been their lack of aptitude. This study challenged that notion by integrating theories of cognitive style, academic emotion, self-efficacy, and motivation to explain students’ academic achievement and perseverance in STEM when transitioning to college. A sample of

The Ordovician Tøyen Shale Formation of the recently retrieved Fågelsång-3 drill core provides some important information on the graptolite biostratigraphy of the unit and its completeness in the region. The drill core reached downwards into the Kiaerograptus supremus Biozone of late Tremadocian age. Above a major fault zone, faunas with a number of specimens referred to Pseudophyllograptus densus

The specific way the Athenians set up their democracy presents both theoretical and empirical challenges. Decisions were taken by majority vote in the Assembly. To keep politicians in line, the Athenians first used ostracism, which however was replaced by the graphe paranomon around 415 BCE. The latter provided that anybody who had made a proposal in the Assembly could be accused of having made an

A socially mixed population is a political ambition in Stockholm. By providing a mix of tenure alternatives throughout all neighbourhoods this objective could, at least partially, be fulfilled. Since current tenure proportions display a weak balance in many neighbourhoods it could be assumed that governing politicians – by primarily utilizing Stockholm’s vast landownership and municipal housing de

Purpose: This study aimed to evaluate predictors of testing uptake among unselected breast cancer patients who were offered germline BRCA1/2 testing in a prospective study. Methods: Pretest information was provided by a standardized invitation letter instead of in-person counseling. Data was abstracted from medical records. Using multivariate logistic regressions, predictors of testing uptake were

Background: The 10-m walk test (10MWT) is a widely used measure of gait speed in Parkinson’s disease (PD). However, it is unclear if different standardizations of its conduct impact test results. Aim of the study: We examined the clinical significance of two aspects of the standardization of the 10MWT in mild PD: static vs. dynamic start, and a single vs. repeated trials. Implications for fall pre

For decades, the media have frequently been instrumental in framing rape cases by linking the deed with the place. This study demonstrates that law courts are not innocent of such social framing; on the contrary, they are significant agents. We argue that courts, by shaping the plot in rape cases, participate in an ongoing cultural production of meaning, although in a more subtle and ambivalent wa

Background: Severe diminished foot somatosensation, for example, caused by neuropathies and advanced aging, contributes to balance deficits and increased fall risk. However, little is known about somatosensory impairment and functional and subjective balance problems in relatively healthy elderly. Method: Vibration perception thresholds (VPTs) were assessed with a biothesiometer and tactile pressuBackground: Severe diminished foot somatosensation, for example, caused by neuropathies and advanced aging, contributes to balance deficits and increased fall risk. However, little is known about somatosensory impairment and functional and subjective balance problems in relatively healthy elderly. Method: Vibration perception thresholds (VPTs) were assessed with a biothesiometer and tactile pressu