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Needle biopsies on autopsy prostates: sensitivity of cancer detection based on true prevalence

BACKGROUND: It is difficult to estimate the diagnostic accuracy of biopsy for prostate cancer because men with negative biopsy do not undergo radical prostatectomy and thus have no confirmation of biopsy findings. METHODS: We performed 18-core needle biopsies on autopsy prostates from 164 men who had no history of prostate cancer. Six-core biopsies were taken from each of the mid peripheral zone (

Apgar scores at 5 minutes after birth in relation to school performance at 16 years of age.

OBJECTIVE: : To estimate the association between an Apgar score of less than 7 at 5 minutes after birth and long-term cognitive function. METHODS: : A linkage between the Swedish Medical Birth Registry and the Swedish School Grade Registry was performed. All singletons born from 1973 to 1986 after 36 6/7 weeks of gestation to Swedish-born women were included. Fetuses that were stillborn, newborns

Histopathology indicates lymphatic spread of a pelvic retroperitoneal ectopic pregnancy removed by robot-assisted laparoscopy with temporary occlusion of the blood supply.

Abstract Retroperitoneal ectopic pregnancies are extremely rare and a diagnostic and therapeutic challenge as an early diagnosis is difficult and all treatments entail a risk for severe bleeding. We present a case of a live completely retroperitoneal ectopic pregnancy in the right obturator fossa. Following 3D color Doppler vaginal ultrasonography to evaluate the relation to larger blood vessels t

Neutrophil Extracellular Traps That Are Not Degraded in Systemic Lupus Erythematosus Activate Complement Exacerbating the Disease.

Ongoing inflammation including activation of the complement system is a hallmark of systemic lupus erythematosus (SLE). Antimicrobial neutrophil extracellular traps (NETs) are composed of secreted chromatin that may act as a source of autoantigens typical for SLE. In this study, we investigated how complement interacts with NETs and how NET degradation is affected by complement in SLE patients. We

Voluntary Activation of the Knee Extensors in Chronic Poststroke Subjects.

Miller M, Flansbjer U-B, Lexell J: Voluntary activation of the knee extensors in chronic poststroke subjects. OBJECTIVE:: To assess the extent to which knee extensor muscle weakness in subjects with chronic mild to moderate poststroke hemiparesis is caused by a decreased voluntary activation. DESIGN:: Forty community dwelling and ambulant men and women (mean age, 59.8 +/- 5.5 yrs) with residual he

Therapist attitudes and strategies to client-centred approaches in the provision of mobility devices to older clients.

Abstract Purpose: This study explored therapists' attitudes to and strategies for developing client-centred approaches in relation to the provision of mobility devices. Method: Four physiotherapists and eight occupational therapists in a Swedish municipality context were interviewed according to a semi-structured interview guide. Data collection and analysis were guided by a qualitative approach,

The propagation of positive streamers in a weak and uniform background electric field

The results of numerical simulations of a positive streamer development in air in a weak and uniform electric field are presented. Streamer dynamics is considered in an electrode gap of 33 mm in length and the configuration was 'protrusion on a plate-plate'. This particular configuration was chosen in order to perform direct comparison between simulated results and experimental data. The electrost

Vilken religion är sann och frågan om språkets obestämbarhet

There is nothing strange in asking what is true. There is nothing strange in asking whether what different religions proclaim is true, and if there is one of them that would be truer than others. Such questions surface when religions meet in various ways. How definite the answers can be depends on the level of linguistic stability, or so it is argued in this article. Therefore, understanding the f

Retinal function and PKC alpha expression after focal laser photocoagulation.

PURPOSE: To examine the effects of focal laser photocoagulation on general and local retinal function and to relate electrophysiological findings with changes in protein kinase C (PKC) alpha expression. METHODS: Twelve rabbits were treated with 70 spots of laser photocoagulation in the central cone-rich retina. The operated eyes were investigated with electroretinography (full-field ERG and multif