Background: Animal models of human diseases are often used in biomedical research in place of human subjects. However, results obtained by animal models may fail to hold true for humans. One way of addressing this problem is to make animal models more similar to humans by placing human tissue into animal models, rendering them chimeric. Since technical and ethical limitations make neurological dis

Att låta de som omtalas i samhällsdebatten själva ta makten över sina egna berättelser.En muralmålning är ett kaxigt utropstecken i betongen: Lyssna på oss, hör våra berättelser! Det här är vårt område och våra liv! I den här handboken delar Förorten i Centrum med sig av en rad konkreta metoder för hur du skapar engagemang i ett område och tar muralprojektet från start till färdig målning – och vi

“Fram” i kapitlets titel, “att skriva fram den andra”, är valt med omsikt. Det syftar till att lyfta fram textens förmåga att skapa det den beskriver. Texter som beskriver “kvinnor”, “homosexuella”, “arbetarklassen” eller “invandrare” skapar först kvinnor, homosexuella, arbetarklassen eller invandrare som befintliga grupper värda att skildra. Därefter skriver man om dessa grupper som om de r

When is the right time to start up a social venture? How should it price its first services? What constituencies should be considered when shaping the board? What collaborations should the venture establish? When is it time to expand? And to close down? How can long-term economic sustainability be achieved? Which scaling-up strategy is most appropriate? How can social impact be assessed? These are

Intranasal oxytocin (OT) has previously been found to increase spirituality, an effect moderated by OT-related genotypes. This pre-registered study sought to conceptually replicate and extend those findings. Using a single dose of intranasal OT vs placebo (PL), we investigated experimental treatment effects, and moderation by OT-related genotypes on spirituality, mystical experiences, and the sens

This chapter deals with culture and identity in management studies. An interest in culture and identity can be understood as an interest in the symbolic side of the organization that deals with meaning, interpretation, symbols and action (rather than behavior). The symbolic side of enterprise has always been present in organization studies; since the early 1980s, however, this has predominantly be

The literature on social entrepreneurship continues to grow. This research is novel and vibrant, yet erratic and fragmented. In this chapter I first organize the burgeoning social-entrepreneurship literature into two streams: one conceptual stream concerned with defining social entrepreneurship; a second management- oriented stream concerned with the establishment and development of social venture

Technological development, in particular the development of information and communicatiion technologies (ICT), is often presented as the answer to many social problems. Proponents of the Information Society suggest that poverty, failing integration, unemployment, and llack of democracy can be addressed with the appropriate technological means. Inequality iis often framed in terms of a digital divi

BACKGROUND: When participating in contact sports, (mild) head trauma is a common incident-observed in both professional and amateur sports. When head trauma results in transient neurological impairment, a sports-related concussion has occurred. Acute concussion, repetitive concussions, as well as cumulative "sub-concussive" head impacts may increase the risk of developing cognitive and behavioral

Background: The optimal treatment of symptomatic perineural (Tarlov) cysts is controversial. Numerous surgical techniques have been proposed with conflicting results. A series of Tarlov cysts treated with a novel surgical approach is presented.Methods: Patients with surgically treated symptomatic perineural cysts during 2013-2016 were included. The main indications for surgery were persistent radi

OBJECTIVEIncreased intracranial pressure (ICP) in patients with severe traumatic brain injury (TBI) with diffuse axonal injury (DAI) is not well defined. This study investigated the occurrence of increased ICP and whether clinical factors and lesion localization on MRI were associated with increased ICP in patients with DAI.METHODSFifty-two patients with severe TBI (median age 24 years, range 9-61

Imagine one Brit, one Dutch, two North Americans, one Spaniard and three Swedes setting up a joint international research project. Their areas of expertise vary: sociology, labour law and organisational theory. The scene is taking place in a hotel conference room in Uppsala. The North Americans are tired from the long trip and the jet-lag. The Spaniard arrived later than everybody, including himse

Phenotypic changes of myeloid cells are critical to the regulation of premature aging, development of cancer, and responses to infection. Heme metabolism has a fundamental role in the regulation of myeloid cell function and activity. Here, we show that deletion of heme oxygenase-1 (HO-1), an enzyme that removes heme, results in an impaired DNA damage response (DDR), reduced cell proliferation, and