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Bioartificial nerve graft for bridging extended nerve defects in rat sciatic nerve based on resorbable guiding filaments
A long defect (15 mm) in rat sciatic nerve was repaired with a bioartificial nerve graft composed of a silicone tube and seven synthetic filaments of five types (polyamide, catgut, polydioxanone, and two types of polyglactin, normal and quickly-absorbed) inserted longitudinally into the tube. In all cases in which filaments were used a regenerating bridge was obtained in the tube after three month
Bullying, pain and analgesic use in school-age children
Aim: The aim of this study was to examine whether the self-reported use of analgesics is associated with being a victim of bullying. Methods: This cross-sectional, school-based survey included all students in grades 6 (11 years old), 8 (13 years old) and 10 (15 years old) in Iceland (response rate: 84%; n = 11 018). The students filled out an anonymous standardised questionnaire: the Icelandic Con
Highly Personal / Deeply Collective Towards a Minor Urbanism in Recent Makings of Public Space
Konferensbidrag, Feminist Philosophy: Rethinking Public Space, University of Oslo, Norway, March 2018
Sorbitol and myo-inositol levels and morphology of sural nerve in relation to peripheral nerve function and clinical neuropathy in men with diabetic, impaired, and normal glucose tolerance
Aims: Sorbitol and myo-inositol levels and morphology of sural nerve were compared with nerve function and clinical neuropathy in men with diabetic, impaired (IGT), and normal glucose tolerance. Methods: After neurography of sural nerve and determinations of sensory thresholds for vibration, warm and cold on the foot, whole nerve sural nerve biopsy was performed in 10 men with Type 1 diabetes mell
Analyzing savannah vegetation phenology with remotely sensed data, lagged time-series models and phenopictures
It is predicted that savannah regions will see changes in precipitation patterns due to current climate change pro-jections. The change will most likely affect leaf phenology which controls net primary production. It is thereforeimportant to; 1) study those changes and its drivers, 2) to be able to correctly model the changes to vegetationphenology due to climate change. To our knowledge there is
Cigarette smoke particles-induced airway hyperreactivity in vivo and in vitro
Cigarette smoke is a well-known strong risk factor for inducing airway hyperreactivity (AHR), but the underlying molecular mechanisms are not fully understood. In the present study, mouse in-vivo and in-vitro models were used to study effects of dimethyl sulfoxide (DMSO)-extracted cigarette smoke particles (DSP) on the airway, and to explore the underlying molecular mechanisms that are involved in
A World Exhibition in Nørrebro, Copenhagen: Planning, Designing and Spacing Communities of Difference
Konferensbidrag, PSUC, Public Spaces and Urban Cultures Series UNSTABLE GEOGRAPHIES – DISLOCATED PUBLICS, Cyprus, May 2018Article submitted to PSUC 2018
Axonal outgrowth in muscle grafts made acellular by chemical extraction
Purpose: To compare nerve regeneration in autologous detergent extracted and freeze-thawed muscle grafts and to electrophoretically characterize the grafts. Methods: Autologous acellular muscle grafts were created either by freeze/thawing or by detergent extraction and then used to bridge a 10 mm gap in rat sciatic nerve. The autologous grafts were compared with respect to protein content, using e
"We Got to Know There Are 70 Nationalities” - Designed Fragmentation and the Disorderly Work of Institutional Change in two Recent Makings of Public Space in Scandinavia
Konferensbidrag, AESOP Annual Congress, Making Space for Hope, Gothenburg, July 2018
Hyperbaric oxygen treatment has different effects on nerve regeneration in acellular nerve and muscle grafts
Effects of hyperbaric oxygen treatment (HBO) on nerve regeneration in acellular nerve and muscle grafts were investigated in rats. Nerve and muscle grafts were made acellular by freeze-thawing and the obtained grafts were used to bridge a 10-mm gap in the sciatic nerve on the left and right sides, respectively. Rats were treated with HBO (100% oxygen for 90 minutes at 2.5 atmospheres absolute pres
Vibration-induced hand problems : Role of the peripheral nerves in the pathophysiology
A substantial number of people who are exposed to vibrating hand-held tools develop vasospastic and sensorineural symptoms that may seriously affect the ability to work. Apart from the discomfort of the disease itself, this leads to socio-economic problems for the patients and high costs for the society. The diagnosis of the neurological symptoms is sometimes difficult and may be misinterpreted as
A practical guide to active stand testing and analysis using continuous beat-to-beat non-invasive blood pressure monitoring
Purpose: The average adult stands approximately 50–60 times per day. Cardiovascular responses evoked during the first 3 min of active standing provide a simple means to clinically assess short-term neural and cardiovascular function across the lifespan. Clinically, this response is used to identify the haemodynamic correlates of patient symptoms and attributable causes of (pre-)syncope, and to det
Elecsys® Total-Tau and Phospho-Tau (181P) CSF assays : Analytical performance of the novel, fully automated immunoassays for quantification of tau proteins in human cerebrospinal fluid
Background: Total tau (tTau) and phosphorylated 181P tau (pTau) are supportive diagnostic cerebrospinal fluid (CSF) biomarkers for Alzheimer's disease. Manual CSF tau assays are limited by lot-to-lot and between-laboratory variability and long incubation/turnaround times. Elecsys® Total-Tau CSF and Phospho-Tau (181P) CSF immunoassays were developed for fully automated cobas e analyzers, allowing b
Optimizing selectivity of anion hydrophobic multimodal chromatography for purification of a single-chain variable fragment
Single-chain variable fragments (scFv) are widely used in several fields. However, they can be challenging to purify unless using expensive Protein L-based affinity adsorbents or affinity tags. In this work, a purification process for a scFv using mixed-mode (MM) chromatography was developed by design of experiments (DoE) and proteomics for host cell protein (HCP) quantification. Capture of scFv f
Advanced radiological work-up as an adjunct to decision in early reconstructive surgery in brachial plexus injuries
Background: As neurophysiologic tests may not reveal the extent of brachial plexus injury at the early stage, the role of early radiological work-up has become increasingly important. The aim of the study was to evaluate the concordance between the radiological and clinical findings with the intraoperative findings in adult patients with brachial plexus injuries.Methods: Seven consecutive male pat
Current trends in the surgical management of Dupuytren's disease in Europe : The surgeon's perspective
Introduction: Dupuytren's disease (DD), commonly affecting European men, is generally treated with surgery. Methods: Orthopaedic and plastic surgeons who had been practicing for >3 and <30 years and operated on ≥5 patients with DD between September and December 2008 were surveyed in 12 European countries (Czech Republic, Denmark, Finland, France, Germany, Hungary, Italy, The Netherlands, Poland, S
Current trends in the surgical management of Dupuytren's disease in Europe : An analysis of patient charts
Introduction: Dupuytren's disease (DD) causes progressive digital flexion contracture and is more common in men of European descent. Methods: Orthopaedic and plastic surgeons in 12 European countries (the Czech Republic, Denmark, Finland, France, Germany, Hungary, Italy, The Netherlands, Poland, Spain, Sweden and the UK) with >3 and <30 years experience reviewed the medical charts of five consecut
The man in sexual commerce
Expanding Architecture: Critical perspectives from within a school of architecture
Konferensbidrad, 10:e Pedagogiska inspirationskonferensen, December 2018, LTHThe architectural community needs to be better at managing a diversity of experiences, desires and needs associated with architecture. How can students' call for a more problematizing and inclusive education and industry be used as a basis for student and teacher collaboration, as well as an educational platform for raising diversity issues? The Symposium Expanding Architecture - Critical Perspect