Let S be the random walk obtained from “coin turning” with some sequence {pn}n≥2, as introduced in [8]. In this paper we investigate the scaling limits of S in the spirit of the classical Donsker invariance principle, both for the heating and for the cooling dynamics. We prove that an invariance principle, albeit with a non-classical scaling, holds for “not too small” sequences, the order const·n−

Background: Survival in malignant cutaneous melanoma has improved but increasing survival will result in an increased likelihood of the occurrence of second primary cancers (SPCs). SPCs may adversely interfere with survival. We quantified survival in patients with different types of SPCs, in comparison to known poor prognostic indicators of metastatic disease. Methods: Data for melanoma and any SP

Aim: The aim of the study was to identify sociodemographic, disease-related, physical and mental health-related determinants of fatigue at 2-year follow-up in individuals with symptomatic knee osteoarthritis (OA). Methods: A longitudinal analysis of participants with symptomatic knee OA from the Multicenter Osteoarthritis Study (MOST) was conducted to identify predictors of fatigue at 2-year follo

The house sparrow is an important model species for studying physiological, ecological and evolutionary processes in wild populations. Here, we present a medium density, genome wide linkage map for house sparrow (Passer domesticus) that has aided the assembly of the house sparrow reference genome, and that will provide an important resource for ongoing mapping of genes controlling important traits

Resilience has been raised as a core task within disaster risk reduction frameworks, yet it remains difficult to implement these global ideas in local communities. This study used Community Based Resilience Analysis Approach to investigate the components that are perceived as important in resilience and the extent to which these components have been achieved. It explored the trend of resilience an

In this study, we examined the evolutionary outcome of and interplay between historic isolation and current selection pressures on traits more or less closely connected to fitness in the Pearly Heath butterfly (Coenonympha arcania) across its range in Europe. We hypothesized that a trait mean is more related to historic events if it has low connection to fitness, while a trait more closely connect

Background and purpose — Cemented fixation is regarded as the gold standard in total knee arthroplasty (TKA). Among working-age patients, there has been controversy regarding the optimal fixation method in TKA. To address this issue, we conducted a register-based study to assess the survivorship of cemented, uncemented, hybrid, and inverse hybrid TKAs in patients aged < 65 years. Patients and meth

The International Working Group on the Diabetic Foot (IWGDF) has published evidence-based guidelines on the prevention and management of diabetic foot disease since 1999. This guideline is on the diagnosis, prognosis, and management of peripheral artery disease (PAD) in patients with foot ulcers and diabetes and updates the previous IWGDF Guideline. Up to 50% of patients with diabetes and foot ulc

A smart power management strategy is needed to economically manage local production and consumption while maintaining the balance between supply and demand. Finding the best-distributed generators’ set-points and the best city demand scheduling can lead to moderate and judicious use out of critical moments without compromising smart city residents’ comfort. This paper aimed at applying the Particl

The origin of the more than 100 km wide Lycksele ring structure in Sweden has puzzled geoscientists for years. In this short note we present results from field analysis, detailed sampling and laboratory analysis executed in search for evidence of an impact, e.g. shatter cones and shock features in minerals. Both approaches gave negative results and consequently an impact origin could neither be co

The alarming loss of pollinator diversity world-wide can reduce the productivity of pollinator-dependent crops, which could have economic impacts. However, it is unclear to what extent the loss of a key native pollinator species affects crop production and farmer's profits. By experimentally manipulating the presence of colonies of a native bumblebee species Bombus pauloensis in eight apple orchar

Sustainability science is an integrative scientific field embracing not only complementary but also contradictory approaches and perspectives for dealing with an array of sustainability challenges.In this chapter we distinguish between pluralism and unification as two main and distinctly different approaches to knowledge integration in sustainability science. To avoid environmental determinism, fu

The interaction of antikaons with nucleons and nuclei in the low-energy regime represents an active research field in hadron physics with still many important open questions. The investigation of light kaonic atoms is, in this context, a unique tool to obtain precise information on this interaction. The most precise kaonic hydrogen measurement to date, together with an exploratory measurement of k

Aims/hypothesis: It is well established that physical activity, abdominal ectopic fat and glycaemic regulation are related but the underlying structure of these relationships is unclear. The previously proposed twin-cycle hypothesis (TC) provides a mechanistic basis for impairment in glycaemic control through the interactions of substrate availability, substrate metabolism and abdominal ectopic fa

An isotropic gradient-enhanced damage model is applied to shape optimisation in order to establish a computational optimal design framework in view of optimal damage distributions. The model is derived from a free Helmholtz energy density enriched by the damage gradient contribution. The Karush–Kuhn–Tucker conditions are solved on a global finite element level by means of a Fischer–Burmeister func

This study examines how university teachers in two Swedish higher education institutions grapple with the challenge of connecting research and teaching. With the increasing pressure in higher education to improve graduate employability, teaching is expected to include skills-oriented, vocational training which may (or may not) conflict with the more traditional Humboldtian ideal, in which teaching

We present an in-depth analysis of the surface band alignment and local potential distribution of InP nanowires containing a p-n junction using scanning probe and photoelectron microscopy techniques. The depletion region is localized to a 15 nm thin surface region by scanning tunneling spectroscopy and an electronic shift of up to 0.5 eV between the n- A nd p-doped nanowire segments was observed a