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Background Circadian rhythms regulate immune cell trafficking and function, and emerging clinical data suggest that the timing of immune checkpoint inhibitor (ICI) administration may influence efficacy. In advanced disease, later-day administration has been associated with inferior outcomes. Whether this applies to neoadjuvant ICI in resectable stage III–IV melanoma is unknown. Methods This retros
With zoonotic outbreaks on the rise, rapid and accurate infectious disease diagnostics are critical for both human and animal health. Traditional lateral flow assays lack sensitivity and specificity, while isothermal amplification methods like LAMP, though rapid, can be hindered by optical detection issues. We present an electrochemical nucleic acid amplification test (NAAT) that combines isotherm
The human stomach is a harsh and fluctuating environment for bacteria with hazards such as gastric acid and flow through of gastric contents into the intestine. H. pylori gains admission to a stable niche with nutrient access from exudates when attached to the epithelial cells under the mucus layer, whereof adherence to glycolipids and other factors provides stable and intimate attachment. To reac
BACKGROUND AND OBJECTIVE: Chronic breathlessness is common and often leads to avoidance of symptom-provoking activities. Expectations of breathlessness influence behaviour and symptom perception, but the accuracy of these expectations remains unclear. The aim of this study was to examine the relationship between expected and experienced breathlessness, the moderating role of mental states, determi
Background Obstructive sleep apnea (OSA) is highly prevalent in patients with coronary artery disease (CAD) and is associated with autonomic dysfunction and adverse cardiovascular outcomes. Exercise-derived autonomic markers provide an integrated assessment of cardiovascular autonomic regulation. Whether baseline OSA severity and longitudinal autonomic adaptation during continuous positive airway
Mechanical circulatory support (MCS) devices provide hemodynamic stability during high-risk percutaneous coronary interventions (HR-PCI), potentially reducing the incidence of adverse events and permitting more complete revascularization.1,2 According to clinical guidelines in the United States, MCS is recommended during PCI for selected high-risk patients undergoing coronary artery revascularizat
Extreme meteorological events are projected to increase in both frequency and intensity as climate change progresses, placing greater demands on accurate hydrological modelling for flood risk assessment and infrastructure design. In Sweden, the process-based S-HYPE model is widely used to simulate streamflow across approximately 26340 catchments, but like many regional rainfall-runoff models it sy
Detta arbete undersöker de mentala och gehörsmässiga processernas dess roll i instuderingsprocesser. Gehörsmetoden som undersöktes var gestaltning med sång. Denna metod kallar jag för vokalisering. Två enklare fiolstycken av Telemann studerades in med en systematisk och reproducerbar övningsmetod – det första med konventionell instrumentövning, och det andra endast med vokalisering. Utvärderingen
Syftet med denna masteruppsats var att utforska min egen kompositionsprocess när jag komponerar musik till en animerad film med hjälp av en analys av John Powells musik i How To Train Your Dragon. Första delen var att analysera tre olika scener ur filmen How To Train Your Dragon. Där gick jag igenom scenens berättelse och musikens olika delar och teman. Jag kunde med hjälp av analysen skapa en bät
Today, airports often prioritise logistics and passenger flow over hospitality, leaving travellers without suitable spaces in which they can rest during long journeys. This thesis aims to address this issue by developing a furniture concept that offers passengers a safe and comfortable place to sleep. Five research methods were used to provide input for the design: qualitative interviews, a quan
This master's thesis project aims to stimulate discussion on the issue of ceramic waste disposal through speculative design. Ceramic waste is unavoidable in ceramic production, and the most common method of disposal is direct landfill. However, these ceramic materials are difficult to degrade and can persist for thousands of years. This speculative design project hopes to raise awareness and c
The region of Istria, a renowned touristic destination, is often represented by superficial souvenirs designed and manufactured far from the place they claim to embody. To challenge this situation, and therefore provide both visitors and locals with meaningful and useful keepsakes, “in tola!” was developed: a collection of dining table utensils for shared dining moments designed with Istria in min
The quantification of microstructural features is essential in materials science, as the microstructure can be linked with the mechanical performance of the material. Gray cast iron (GCI) is a type of cast iron used mainly for its excellent machinability and vibration damping, along with high compressive strength and good thermal conductivity. GCI is characterized by graphite flakes dispersed in a
What happens when a huge banana is placed in a town square? This thesis asks this question, but also challenges the design world to think more playfully and explores whether that approach can create genuine interaction. The project is based on the premise that design students have the privilege of not being bound by strict corporate guidelines, and should therefore use that freedom to create thi
Telecommunication has become a cornerstone of modern society, enabling coordination, safety, and daily life. During natural disasters, however, this essential infrastructure is often compromised by power outages or direct damage caused by floods, earthquakes, and severe winds. To address this, Ericsson Response, a dedicated unit within Ericsson, deploys to affected regions to establish temporary n
Kriminella nätverk och gängrelaterat våld har under de senaste decennierna fått ökad uppmärksamhet i Sverige. Forskningen har tidigare huvudsakligen fokuserat på den gängkriminella mannen, medan kvinnors roller och erfarenheter har fått mindre utrymme. Denna uppsats syftar till att undersöka hur kvinnor med koppling till kriminella nätverk framställs i svensk nyhetsrapportering. Vidare syftar upps
Defending war in the name of human rights: A discourse analysis of Sweden's participation in ISAF. Despite the country’s past military non-alignment, Sweden still actively participated in the combat mission of ISAF for twelve years. This study aims to produce new knowledge of how human rights are portrayed in the Swedish parliamentary debates on international operations. The study uses a d
Denna uppsats undersöker hur högerpopulistiska partigrupper i Europaparlamentet ramar in frågor om sexuell och reproduktiv hälsa och rättigheter i politisk text och på vilket sätt ett rättighetsspråk används i denna inramning. Med utgångspunkt i en teori om strategisk rättighetsinramning analyseras fyra partigruppers resolutionsförslag och politiska publikationer under de två senaste mandatperiodeOn the strategic use of rights: a qualitative text analysis of how right-wing populist political groups in the European Parliament frame issues of sexual and reproductive health and rights. This thesis examines how right-wing populist political groups in the European Parliament frame issues of sexual and reproductive health and rights in political text and how a rights language is used within thes
Sammanfattning Syfte: Denna studie utforskar hur redovisare skapar mening kring AI, och hur denna process formas av yrkesidentitet, känslomässiga förhållningssätt och organisatoriska sammanhang. Den adresserar ett forskningsgap genom att flytta fokus från tekniska aspekter till ett människocentrerat perspektiv på teknologisk förändring. Metod: En kvalitativ metod med en induktiv ansats antogs f
