Search results

Lower birth weight has a negative association with adult BMC and body composition in young adult Swedish women. INTRODUCTION: The aim of this study was to evaluate the influence of birth weight on peak bone mass and body composition in a cohort of 25-year-old women. METHODS: One thousand sixty-one women participated in this cross-sectional population-based study using dual energy X-ray absorpt

Many animal species have populations in which some individuals migrate and others remain on the breeding grounds. This phenomenon is called partial migration. Despite substantial theoretical work, empirical data on causes and consequences of partial migration remain scarce, mainly because of difficulties associated with tracking individuals over large spatial scales. We used stable hydrogen isotop

In the present work non-idealities of flat burner-stabilized flames at atmospheric and low pressures are examined using PIV measurements, which are supported by and analyzed with the help of CFD modeling. Radial and axial velocity profiles measured in the cold flow and in the flames at atmospheric and at lower pressures are presented. Two possible reasons for the drop in the apparent laminar burni

The goal of this paper is to determine concentrations of seven selected perfluoroalkylated substances (PFASs): perfluorooctane sulfonic acid (PFOS), perfluorooctanoic acid (PFOA), perfluorohexane sulfonic acid (PFHxS), perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), perfluoroundecanoic acid (PFUnDA), perfluorododecanoic acid (PFDoDA) in the blood serum of men and women of reproductiv

We dispute the claim by Alexeev (2010) that the numerous fossil meteorites found in mid-Ordovician sediments in southern Sweden can be explained by a single large meteorite shower some 470 million years ago, and-in particular-that the reported variable cosmic ray exposure ages derived from cosmogenic Ne-21 in chromite grains extracted from the fossil meteorites actually reflect variable contributi

Evidence-based Pharmacy was first published as a textbook by Phil Wiffen in 2001. The first chapter was published in Eur J Hosp Pharm 2013;20:308-12

Background: Adjusting medication for uncontrolled asthma involves selecting one of several options from the same or a higher treatment step outlined in asthma guidelines. We examined the relative benefit of introducing budesonide/formoterol (BUD/FORM) maintenance and reliever therapy (Symbicort SMART (R) Turbuhaler (R)) in patients previously prescribed treatments from Global Initiative for Asthma

BACKGROUND: Intestinal injury is a key feature in sepsis. Inhibitors of heat shock protein 90 (Hsp90) have been shown to exert protective effects in models of inflammation. Herein, we hypothesized that Hsp90 might regulate intestinal inflammation and leakage in abdominal sepsis. MATERIALS AND METHODS: Male C57BL/6 mice were pretreated with radicicol (60 mg/kg), which is a specific inhibitor of Hsp

Denkpsychologie has been important for the development of psychology as well as of philosophy during the last century. More specifically, cognitive psychology as well as Karl Popper's evolutionary epistemology were both influenced by Otto Selz's cognitive psychology. Without doubt, Selz played a role in the development of Popper's thinking, but Michel ter Hark has not given convincing evidence for

Specific alterations (mutations, deletions, insertions) of virus genomes are crucial for the functional characterization of their regulatory elements and their expression products, as well as a prerequisite for the creation of attenuated viruses that could serve as vaccine candidates. Virus genome tailoring can be performed either by using traditionally cloned genomes as starting materials, follow

Development of relevant models of Parkinson's disease (PD) is essential for a better understanding of the pathological processes underlying the human disease and for the evaluation of promising targets for therapeutic intervention. To date, most pre-clinical studies have been performed in the well-established rodent and non-human primate models using injection of 6-hydroxydopamine (6-OHDA) or 1-me

A role for the immune system in the pathogenesis of Parkinson's Disease (PD) has previously been suggested. A recent genome-wide association (GWA) study identified an association between one single nucleotide polymorphism (SNP) in the human leucocyte antigen (HLA) region (HLA-DRA rs3129882) and PD in a population of American patients with European ancestry. In that study, the minor rs3129882 allel

Short lead(II) alkanoates, from propionate to heptanoate, show a very intricate and reversible thermal behaviour, presenting crystalline phases and three different glass states (regular or amorphous, liquid crystal and rotator glasses) with different degrees of ordering depending on the alkyl chain length. A thorough thermal study was carried out in order to study the different phases and to analy

The small leucine-rich proteoglycans fibromodulin and lumican are functionally related extracellular matrix proteins involved in the regulation of collagen fiber formation. Fibromodulin-deficient apolipoprotein E-null mice have decreased vascular retention of lipids and reduced development of atherosclerosis suggesting that fibromodulin may influence the disease process. The aim of the present stu

Objective To examine use of magnetic resonance imaging (MRI) of knees with no radiographic evidence of osteoarthritis to determine the prevalence of structural lesions associated with osteoarthritis and their relation to age, sex, and obesity. Design Population based observational study. Setting Community cohort in Framingham, MA, United States (Framingham osteoarthritis study). Participants 710 p

Mutations in the BRCA1 gene substantially increase a woman's lifetime risk of breast cancer. However, there is great variation in this increase in risk with several genetic and non-genetic modifiers identified. The BRCA1 protein plays a central role in DNA repair, a mechanism that is particularly instrumental in safeguarding cells against tumorigenesis. We hypothesized that polymorphisms that alte

This paper describes the preliminary design of the BioMAX beamline at the 3 GeV ring of the MAX IV facility, focusing on the optics and x-ray beam performance. The MAX IV facility will include two storage rings with 1.5 GeV and 3.0 GeV electron energy and a linac serving both as injector for the two rings and feeding a short pulse facility. BioMAX is one of the first seven beamlines funded at the

Dating of sediment cores from the Baltic Sea has proven to be difficult due to uncertainties surrounding the C-14 reservoir age and a scarcity of macrofossils suitable for dating. Here we present the results of multiple dating methods carried out on cores in the Gotland Deep area of the Baltic Sea. Particular emphasis is placed on the Littorina stage (8 ka ago to the present) of the Baltic Sea and

H-2 NMR experiments on a nonionic oriented lamellar phase demonstrate that shear flow induces structural defects in the lamellar structure. These substantial structural changes give rise to a transition from a viscous to a solidlike behavior; the elastic modulus of presheared samples was found to increase, reversibly, with the applied preshear rate. A similar behavior was found when step-cycling t