Endoglin is a transforming growth factor-beta (TGF-beta) accessory receptor recently identified as being highly expressed on long-term repopulating hematopoietic stem cells (HSC) However, little is known regarding its function in these cells. We have used two complementary approaches toward understanding endoglin's role in HSC biology: one that efficiently knocks down expression via lentiviral-dri

The motion of paraxial atomic beams in a laser radiation field is studied within the framework of a parabolic equation. Exact analytical solutions of the parabolic equation are found for a variety of potentials featuring a nonuniformity in the propagation direction. Special attention is paid to the propagation of cold atomic beams in the gradient field of the TEM01* laser radiation mode. Explicit

Lifetimes of a superdeformed band in Sr-82 were measured with the centroid shift method. The measured average quadrupole moment of this band corresponds to a quadrupole deformation of beta(2) approximate to 0.49, which is slightly smaller than both the theoretical prediction, and the measured deformation of the SD band in the neighboring isotone Zr-84. Lifetimes of high spin states of three normal

In seeking to advance the understanding of the production, diffusion and negotiation of meaning in and between organisations, we introduce below the notion of mise-en-sens. Mise-en-sens refers to the performing art term of mise-en-sce` ne and builds on the French term sens denoting meaning as well as direction. Starting from a qualitative analysis of how Swedish wind farm developers manage the per

We assessed all patients who underwent tissue expansion, excluding breast reconstructions, between 1984 and 1999. A total of 237 patients had 257 expansions, normally for distorted scars, 202 of 257 cases (79%). Their mean age was 27 (range 7- 67) years, most being women, 149 of 237 (63%). The mean duration of expansion was 16 weeks (range 0.4-118). The most common site was the skull (61/257). Pro

First results are reported from a major new initiative of experiments, which focus on nuclear structure studies at extreme isospin values by means of isomer spectroscopy. The experiments represent the first part of the so-called stopped-beam campaign within the Rare ISotope INvestigations at GSI (RISING) project. Time-correlated gamma decays from individually identified nuclear species have been m

Background Although much is known about the reactivity of polyclonal populations of antibodies targeting the wide array of allergens produced by timothy (Phleum pratense) and other grass species, little is known about the finer details at the level of individual antibody specificities. Objective We sought to investigate the IgE repertoire as it occurs in a patient with grass pollen allergy. Meth

Background The purpose of these studies was to compare efficacy and toxicity of docetaxel alone with the combination of gemcitabine and docetaxel for treatment of metastatic esophageal carcinoma. Patients and methods These studies enrolled patients with histopathologically verified squamous cell carcinoma or adenocarcinoma of the esophagus or cardia. Between March 1997 and June 1999, 52 patients w

In sensitized subjects with allergic rhinitis (AR) or asthma, allergen exposure provokes symptoms. Among non-asthmatics with AR, an association between allergen sensitization, pollen season and lower airway inflammation has been demonstrated. Our aims were to compare AR and asthma with regard to patterns of allergen sensitization, the degree of airway hyperresponsiveness (AHR) and levels of exhale

OBJECTIVES: To test prospectively the diagnostic performance of two logistic regression models for calculation of individual risk of malignancy in adnexal tumors (the 'Tailor model' and the 'Timmerman model'), and to compare them to that of 'pattern recognition' (subjective evaluation of the gray-scale ultrasound image and color Doppler ultrasound examination). DESIGN: Consecutive women with a pel

In this note, we study the extension of the class of linear time invariant plants that may be transformed into SPR systems introducing an observer. It is shown that for open loop stable systems a cascaded observer achieves the result. For open loop unstable systems an observer-based feedback is required to succeed. In general any stabilizable and observable system may be transformed into an SPR sy

The first stories about Kluskap, the culture hero of the Mi’kmaq in eastern Canada, were written down at the end of the 19th century. The romantic epoch and the environmental failures of industrialism had generated a growing interest for the “Indian”, who seemed to inherit the continent’s authentic “poetry of the Volk” and harbour deep wisdom about nature. The first written literature about Kluska

This article argues against lesbophobia in Swedish feminist politics and theory and opens up a perspective for feminist solidarity.

Sulfate adsorption was implemented in the dynamic, multi-layer soil chemistry model SAFE. The process is modeled by an isotherm in which sulfate adsorption is considered to be fully reversible and dependent on sulfate concentration as well as pH in soil solution. The isotherm was parameterized by a site-specific series of simple batch experiments at different pH (3.8–5.0) and sulfate concentration