Background: Synaptic degeneration is an early pathogenic event in Alzheimer's disease, associated with cognitive impairment and disease progression. Cerebrospinal fluid biomarkers reflecting synaptic integrity would be highly valuable tools to monitor synaptic degeneration directly in patients. We previously showed that synaptic proteins such as synaptotagmin and synaptosomal-associated protein 25

Background: Increasing evidence suggests that general obesity [measured by body mass index (BMI)] is positively associated with risk of esophageal adenocarcinoma (EAC). In contrast, previous studies have shown inverse relations with esophageal squamous cell carcinoma (ESCC). However, it is still unclear whether body fat distribution, particularly abdominal obesity, is associated with each type of

Conflicts of interest within hierarchic government organizations regarding the importance of fiscal discipline create the need for institutions that curb the bargaining power of units in charge of implementing policy and align their incentives to the interests of the whole organization. We examine this general public sector problem by collecting unique data on budget institutions and conflicts of

The penetration of financialization into the biocultural geographies of islands builds upon processes of commodification and privatization of environments, entailing enclosures of resource commons, environmental destruction and displacement of people, their livelihoods, knowledge and practices, with implications for sustainability. Against this background I critique the growing literature on acron

Popular Abstract in Swedish Den värld vi lever i drivs till stora delar av förbränning. Det mesta vi gör kräver energi, elektricitet för matlagning och bensin eller diesel för transporter. Sett över hela världen kommer den största delen av den energi som förbrukas från förbränning. Främst är det fossila bränslen, olja och kol, som används, men en ökande del kommer från förnyelsebara bränslen. Vid The work reported here includes experimental studies of lean premixed swirling flames. Various laser-based optical diagnostic techniques were used to collect information under different operational conditions. Combined flow- and scalar field measurements were performed at high repetition rates for detailed studies of the turbulent flames. A large part of the work presented concerns experimental

Left atrial (LA) enlargement is a pathophysiological response to volume overload resulting from chronic mitral regurgitation (MR), is known as LA remodeling, and has been shown previously to be associated with cardioembolic events. Following mitral valve surgery (MVS), the left atrium may undergo reverse remodeling characterized by LA volume reduction. The study aim was to evaluate the incidence a

This article aims to share experience from a Swedish project on the introduction and implementation of Open Educational Resources (OER) in higher education with both national and international perspectives. The project, OER – resources for learning, was part of the National Library of Sweden Open Access initiative and aimed at exploring, raising awareness of and disseminating the use of OER and th

Objective. The first changes in the diabetic kidney are glycogen deposits in the epithelial cells of the thick ascending limb of Henle. These cells produce Tamm-Horsfall protein (THP). Is low excretion of THP associated with the development of renal insufficiency or cardiovascular disease? Material and methods. Urine samples were collected at baseline in patients with type 1 (n=131) and type 2 (n=

BACKGROUND: The chosen method of speech assessment, including type of speech material, may affect speech judgement in children with cleft palate.AIM: To assess the effect of different speech materials on speech judgement in 5-year-old children born with or without cleft palate, as well as the reliability of materials by means of intra- and inter-transcriber agreement of consonant transcriptions.ME

Consider a parametrized family of general hidden Markov models, where both the observed and unobserved components take values in a complete separable metric space. We prove that the maximum likelihood estimator (MLE) of the parameter is strongly consistent under a rather minimal set of assumptions. As special cases of our main result, we obtain consistency in a large class of nonlinear state space

A selective extraction technique based on the combination of membrane assisted solvent extraction and molecularly imprinted solid phase extraction for triazine herbicides in food samples was developed. Simazine, atrazine, prometon, terbumeton, terbuthylazine and prometryn were extracted from aqueous food samples into a hydrophobic polypropylene membrane bag containing 1000 mu L of toluene as the a

The ability to store energy is an important life history trait for organisms facing long periods without energy income, and in particular for capital breeders such as temperate zone amphibians, which rely on stored energy during reproduction. However, large scale comparative studies of energy stores in populations with different environmental constraints on energy allocation are scarce. We investi

Musculoskeletal disorders are very common and affects the individual by pain and functional impairment, and the society through work disability and healthcare utilisation. To what extent is less studied. Routinely collected healthcare registers is a potential resource for epidemiological studies of musculoskeletal disorders. Skåne region, as opposed to nationally in Sweden, has healthcare register

The development of efficient vehicle-to-vehicle (V2V) communications systems requires an understanding of the underlying propagation channels. In this paper, we present results on pathloss, power-delay profiles (PDPs), and delay-Doppler spectra from a high speed measurement campaign on a highway in Lund, Sweden. Measurements were performed at a carrier frequency of 5.2GHz with the communicating ve

Nutritional classification of dietary saccharides considers as indigestible saccharides those that are incompletely or not absorbed in small intestine. Resistant starch (RS) as a part of dietary fibre (DF) is a type of indigestible saccharide. The addition of natural RS from some fruits, legumes or cereals to commonly eaten starchy foods is a good alternative to increase the DF intake representing

The Cd-114(Ca-48, 6n gamma) reaction at 215 MeV has been investigated using the Gammasphere spectrometer to study the high-spin structure of the nucleus Er-156(68)88. Many new transitions have been established along with 68 definitive spin-parity level assignments from a high-fold angular-distribution analysis. In addition, absolute B(M 1) and B(E 1) strengths have been inferred from measured gamm

Molecular imprinting is one of the most efficient methods for preparing synthetic receptors that possess user defined recognition properties. Despite general success of non-covalent imprinting for a large variety of templates, some groups of compounds remain difficult to tackle due to their structural complexity. In this study we investigate preparation of molecularly imprinted polymers that can b

Abstract in UndeterminedThe recent contribution by Benjamin Sovacool proposes 20 dimensions and 320 indicators of energy security in Asia. However, the method for identifying these dimensions and indicators – 64 semi-structured interviews – has three shortcomings. First, Asian policy makers responsible for energy security are absent from the pool of respondents dominated by academics. Second, no p