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Thallium-technetium subtraction scintigraphy of enlarged parathyroid glands after calcitonin stimulation of parathyroid hormone secretion

To improve the sensitivity of thallium-technetium subtraction scintigraphy for preoperative localization procedure of enlarged parathyroid glands in primary hyperparathyroidism, we administered calcitonin intramuscularly 4 hours before the scintigraphy in 14 consecutive patients. Injection of calcitonin reduced plasma levels of ionized calcium from 1.47 +/- 0.10 mmol/l to 1.41 +/- 0.09 mmol/l (p l

A genetic risk score for CAD, psychological stress, and their interaction as predictors of CAD, fatal MI, non-fatal MI and cardiovascular death

Background Psychological stress is an independent risk factor for cardiovascular disease (CVD), but the mechanism by which stress is associated with CVD is not entirely understood. Although genetic factors are implied in both stress responsivity and cardiovascular reactivity, no studies to date have investigated their interactions with stress for cardiovascular end points. The objective was to elu

Coping strategies and cancer incidence and mortality : The Japan Public Health Center-based prospective study

Background Psychological stress is a modifiable risk factor for health outcomes and can be managed through coping mechanisms. Biological and behavioral hypotheses have been proposed to explain the association between stress coping strategies and cancer outcomes. Methods The Japan Public Health Center-based study asked questions on coping behaviors in its 10-year follow-up survey. 55,130 subjects a

Alcohol consumption, genetic variants in the alcohol- and folate metabolic pathways and colorectal cancer risk : The JPHC Study

The association between alcohol intake and colorectal cancer (CRC) may vary secondary to single nucleotide polymorphisms (SNPs) in two pathways related to alcohol intake. 375 cases of CRC were identified among 38 373 Japan Public Health Center-based prospective Study (JPHC Study) participants who had returned a baseline questionnaire, reported no diagnosis of any cancer and provided blood samples.

Coping strategies and risk of cardiovascular disease incidence and mortality : The Japan Public Health Center-based prospective Study

Aims: Coping strategies may be significantly associated with health outcomes. This is the first study to investigate the association between baseline coping strategies and cardiovascular disease (CVD) incidence and mortality in a general population cohort. Methods and results: The Japan Public Health Center-based prospective Study asked questions on coping in its third follow-up survey (2000- 04).

The association between complete and partial non-response to psychosocial questions and suicide : The JPHC Study

Background: Non-participants to psychosocial studies have been shown to have higher mortality, and mortality differs between partial and complete responders to psychosocial questionnaires. Yet, there is very little information available directly linking survey response status with completing suicide. Methods: The study population consisted of the participants of the Japanese Public Health Center-b

Coping behaviors and suicide in the middle-aged and older japanese general population : The japan public health center-based prospective study

Purpose: Cross-sectional studies have shown an association between different coping styles and suicidal behavior. It is unknown whether there is any prospective association between coping behaviors and suicide in the general population. Methods: The study population consisted of participants of the Japanese Public Health Center-based Prospective Study. In the 10-year follow-up questionnaire, subje

Extensive reworking of Archaean crust within the Birimian terrane in Ghana as revealed by combined zircon U-Pb and Lu-Hf isotopes

Located in the southeastern parts of the Baoulé Mossi domain of the West African Craton, the Birimian terrane in Ghana is known to consist of predominantly juvenile crust emplaced during the Eburnean orogeny. Here we present novel coupled zircon U-Pb and Lu-Hf isotope data from nine Birimian granitoids intruding different domains from northwestern, western and southeastern Ghana. Sub-chondritic e(

Technical evaluation of a tank-connected food waste disposer system for biogas production and nutrient recovery

In this study, a tank-connected food waste disposer system with the objective to optimise biogas production and nutrient recovery from food waste in Malmö was evaluated. The project investigated the source-separation ratio of food waste through waste composition analyses, determined the potential biogas production in ground food waste, analysed the organic matter content and the limiting component

Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015 : a novel analysis from the Global Burden of Disease Study 2015

BACKGROUND: National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). Previous analyses of mortality amenable to health care only focused on high-income countries and faced several methodological challenges. In the present analysis, we use the h

Second-look resection for primary stage T1 bladder cancer : a population-based study

Objective: This study aimed to evaluate the use of second-look resection (SLR) in stage T1 bladder cancer (BC) in a population-based Swedish cohort. Materials and methods: All patients diagnosed with stage T1 BC in 2008–2009 were identified in the Swedish National Registry for Urinary Bladder Cancer. Registry data on TNM stage, grade, primary treatment and pathological reports from the SLR perform

Dendritic cell response to HIV-1 is controlled by differentiation programs in the cells and strain-specific properties of the virus

Dendritic cells (DCs) are potent antigen-presenting cells that might play contradictory roles during HIV-1 infection, contributing not only to antiviral immunity but also to viral dissemination and immune evasion. Although DCs are characterized by enormous functional diversity, it has not been analyzed how differentially programmed DCs interact with HIV-1. We have previously described the reprogra

Coreference Resolution for Swedish and German using Distant Supervision

Coreference resolution is the identification of phrases that refer to the same entity in a text. Current techniques to solve coreferences use machine-learning algorithms, which require large annotated data sets. Such annotated Resources are no tavailable for most languages today. In this paper, we describe a method for solving coreferences for Swedish and German using distant supervision that does

The impact of stellar feedback on the density and velocity structure of the interstellar medium

We study the impact of stellar feedback in shaping the density and velocity structure of neutral hydrogen (H I) in disc galaxies. For our analysis, we carry out ~4.6 pc resolution N-body+adaptive mesh refinement hydrodynamic simulations of isolated galaxies, set up to mimic a Milky Way and a Large and Small Magellanic Cloud. We quantify the density and velocity structure of the interstellar medium