Popular Abstract in English Breast cancer is the most common cancer in women worldwide and the leading cause of cancer-related deaths. Although survival rates are low compared to other cancers, more than 500,000 women worldwide die of breast cancer every year. It is however not a single disease but rather a collection of different diseases with similar appearance but distinct molecular mechanisms.Background: Breast cancer is the most common female malignancy and the leading cause of cancer-related deaths worldwide. Targeted therapy against the main biomarkers estrogen receptor alpha (ER) and human epidermal growth factor receptor 2 (HER2/ERBB2) have greatly improved mortality rates, but ab initio or acquired therapy resistance is common. It is imperative to identify patients who will benef

This paper gives embedding theorems for a very general class of weighted Bergman spaces: the results include a number of classical Carleson embedding theorems as special cases. The little Hankel operators on these Bergman spaces are also considered. Next, a study is made of Carleson embeddings in the right half-plane induced by taking the Laplace transform of functions defined on the positive half

Objective: The aim of this study was to explore healthcare workers' opinions on workplace related health resources relevant to promotion of their health. Participants: 16 registered nurses and 19 assistant nurses, from a medical emergency ward at a medium sized hospital in the south of Sweden, participated in the study. Methods: Eight focus group interviews were conducted, the material was con

Popular Abstract in Swedish Rinit är en av våra vanligaste sjukdomar och betyder ordagrant inflammation i näsan. Det är också inflammationen i nässlemhinnan som orsakar de välkända symptomen vid rinit: snuva, nästäppa och klåda i näsan. Inflammationen orsakas av att immun¬försvaret reagerar på ämnen i vår omgivning. Det kan t.ex. vara pollen, som hos de av oss som är allergiska ger allergisk rinitAllergic and infectious rhinitis are prevalent conditions that besides a direct morbidity also causes exacerbations of asthma and chronic obstructive pulmonary disease. The immune mechanisms associated with various forms of rhinitis are not fully understood. The principal aim of this thesis was to examine innate immune mechanisms relevant to allergic and viral rhinitis focusing on the mediators tu

Two nickel(II) complexes, [Ni(L)(2)] (1) and [Ni-2(mu(1,1)-N-3)(2)(L)(2)(DMSO)(2)] (2) [where HL = 3-(methyl-amino)propyliminomethyl-4-bromophenol, a tridentate Schiff base], have been synthesized and characterized by elemental analysis, IR, UV-Vis and fluorescence spectroscopy and single-crystal X-ray diffraction studies. The deprotonated tridentate Schiff base occupies three coordination sites o

The best method to evaluate the seismic site response is by means of borehole vertical arrays that use earthquake records from different depths. In this paper we introduce the implementation of a single borehole sensor system (synchronized to a sensor on the surface) that is fixed at variable depths within a single well. This system is used for recording small amplitude earthquake signals at varia

An improved synthetic procedure of racemic bicyclo[3.3.1]nonane-2,6-dione has been developed. Employing Baker's yeast for sweet dough made it possible to kinetically resolve the racemic compound and to isolate enantiomerically pure (+)-bicyclo[3.3.1]nonane-2,6-dione on a large scale. Furthermore, the developed procedure made it possible to produce (-)-bicyclo[3.3.1]nonane-2,6-dione with an enantio

This paper presents the results of a global sensitivity analysis (GSA) of a phenomenological model that generates dynamic wastewater treatment plant (WWTP) influent disturbance scenarios. This influent model is part of the Benchmark Simulation Model (BSM) family and creates realistic dry/wet weather files describing diurnal, weekend and seasonal variations through the combination of different gene

This work was performed to quantify the performance of extracts and saponins in residues generated by exporters of quinoa in the departments of La Paz, Oruro and Potosi, determining that the extraction yields range from 36.0 % to 39.4 % w/w, while the percentage of saponins in the extract ranged from 47.3 % to 56.2 % and saponins in the residues from 17.3 % to 22.1 %. Additionally, a method was op

Ankylosing Spondylitis (AS) is a chronic inflammatory disease with onset in young adults, but little is known about the prevalence in older age groups. Furthermore, there is very limited information of health status of elderly patients with AS. Our objective was to estimate the prevalence of moderate to severe radiographic sacroiliitis in elderly men and its impact on health.

Synapsins are pre-synaptic vesicle-associated proteins linked to the pathogenesis of epilepsy through genetic association studies in humans. Deletion of synapsins causes an excitatory/inhibitory imbalance, exemplified by the epileptic phenotype of synapsin knockout mice. These mice develop handling-induced tonic-clonic seizures starting at the age of about 3 months. Hence, they provide an opportun

Popular Abstract in Swedish Resenärsinformation utformad för att uppfylla behov och förväntningar hos enskilda resenärer är viktigt för att förbättra resandet i kollektivtrafiken bland äldre personer och personer med funktionsnedsättningar. Det övergripande syftet med den här avhandlingen är att bidra till kunskapen om behov och användning av resenärsinformation bland äldre personer och personer mTraveller information designed to fulfil needs and expectations of individual travellers is a key factor in improving access for older people and people with disabilities to public transport. The overall aim of this thesis is to contribute to the knowledge of user and provider perspectives on the provision of traveller information for older people and people with disabilities in public transport w

In this paper we revisit some facts about thin interpolating sequences in the unit disc from three perspectives: uniform algebras, model spaces, and H-p spaces. We extend the notion of asymptotic interpolation to H-p spaces, for 1

Popular Abstract in Swedish Hemolytiskt uremiskt syndrom (HUS) är den vanligaste orsaken till njursvikt bland barn i västvärlden. HUS kännetecknas av hemolytisk anemi (sönderfall av och brist på röda blodkroppar), trombocytopeni (brist på blodplättar) och akut njursvikt. Den vanligaste formen av sjukdomen, typisk HUS orsakas av Shigatoxinproducerande bakterier, främst olika stammar av EscherichiThis thesis addressed the diagnosis, pathogenesis and clinical course of specific renal diseases hemolytic uremic syndrome (HUS) and dense deposit disease (DDD). HUS may be associated with infection caused by Enterohemorrhagic Escherichia coli (EHEC) or with complement dysfunction due to complement mutations or auto-antibodies (atypical HUS, aHUS). EHEC is a non-invasive highly virulent bacterium

P>Aims To determine health-related quality of life (HRQL) in diabetic and non-diabetic patients with carpal tunnel syndrome (CTS) before and after surgical treatment. Methods In a prospective study, 35 consecutive diabetic patients with CTS were age and gender matched with 31 non-diabetic patients with idiopathic CTS. At baseline (preoperatively), 6, 12 and 52 weeks after surgical carpal tunnel re

In this work we report on the evolution of the structure of two model ionic liquid families, N-alkyl-N-methylpyrrolidinium (Pyr(1n)-TFSI) and 1-alkyl-3-methylimidazolium (C(n)MIm-TFSI) (n = 3, 4, 6 and 8) both containing the bis(trifluoromethanesulfonyl)imide (TFSI) anion, upon the addition of LiTFSI using small angle X-ray scattering (SAXS). The introduction of a lithium salt (Li-salt) tunes the