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Common femtoscopic hadron-emission source in pp collisions at the LHC

The femtoscopic study of pairs of identical pions is particularly suited to investigate the effective source function of particle emission, due to the resulting Bose–Einstein correlation signal. In small collision systems at the LHC, pp in particular, the majority of the pions are produced in resonance decays, which significantly affect the profile and size of the source. In this work, we explicit

Linear-scaling aspherical crystallographic refinement of proteins : A case study for crambin and rubredoxin

Hirshfeld atom refinement (HAR) provides a more realistic interpretation of crystallographic data than the standard independent atom model (IAM) by using aspherical atomic form factors derived from quantum mechanical (QM) calculations. With this aspherical description, it is possible to obtain improved atomic positions, atomic displacement parameters and correct bond lengths even for hydrogen atom

A novel geophysical methodology to characterize past metallurgic sites and deposits

This study is part of a North West Europe (NWE) Interreg project called NWE-REGENERATIS that aims at the regeneration of past metallurgic sites and deposits through innovative circularity for raw materials. A novel geophysical methodology is developed to allow a 2D or 3D characterization of the recoverable metallic particles in terms of volume, type and grain sizes. We propose to integrate multi-m

Search for same-charge top-quark pair production in pp collisions at √s = 13 TeV with the ATLAS detector

A search for the production of top-quark pairs with the same electric charge (tt or tt¯) is presented. The analysis uses proton-proton collision data at s = 13 TeV, recorded by the ATLAS detector at the Large Hadron Collider, corresponding to an integrated luminosity of 140 fb−1. Events with two same-charge leptons and at least two b-tagged jets are selected. Neural networks are employed to define

Nuclear PD-L1 regulates YAP-driven transcription via the PGE2-EP4-YAP-importin α3 axis in solid tumors

Prostaglandin E2 (PGE2) is synthesized by cyclooxygenase 2 (COX-2) in the arachidonic acid pathway. PGE2 promotes cancer initiation and progression while facilitating chronic inflammation and immunosuppression, partly through regulation of programmed death ligand 1 (PD-L1) in tumor cells and tumor-associated macrophages. PGE2 also modulates Hippo signaling, enhancing nuclear Yes-associated protein

CURRENT DEVELOPMENTS IN MEDICAL RADIATION PHYSICS AND RADIATION PROTECTION

The paper reviews current trends and future directions for diagnostics and therapy with ionizing radiation. Recent advances in medical physics applied to radiation therapy, diagnostic radiology, nuclear medicine, MRI, and radiation safety are summarized. Today, much of the development is concentrated on providing conditions for individualized diagnostics and therapy for the patient, which requires

Insulin resistance is associated with incident prediabetes and type 2 diabetes in normoglycemic individuals

Aims: Testing insulin resistance could help improve physician assessment of patients’ risk of prediabetes or type 2 diabetes (T2D), even among normoglycemic individuals. Methods: The longitudinal study followed 16,333 normoglycemic participants in a nation-wide employer-sponsored health assessment program starting in August 2020 with a median follow-up time of 2.9 years for incident prediabetes or

Does clientelism pay off abroad? : Emigrant voting in Southern and Eastern Europe

Some political parties employ clientelist practices to gain voter support. Yet as more citizens now vote from abroad, little is known about parties engaging in clientelism domestically versus transnationally. We propose parties adopt either a replication or differentiation approach, meaning they apply similar or different campaigning strategies abroad. Using a large-N sample of voter turnout in So

AI-driven Quality Control of cell-based ATMPs: Automated, Accurate, and Affordable

The production of neuroepithelial stem (NES) cells, a promising therapeutic candidate for neurological conditions such as stroke and spinal cord injuries, faces significant manufacturing challenges, particularly in quality control (QC). Specifically, current QC methods rely on labor-intensive manual assessments that are costly, time-consuming, and subject to operator bias, limiting scalability and

A radical rejection of spectrum arguments

Spectrum arguments are purported to show that the betterness relation is not a transitive relation. This is a drastic conclusion since much normative theorizing and everyday reasoning assume that betterness is transitive. In order to avoid this conclusion, many reject a plausible view on trade-offs between quality and quantity. The rejection can take the form of a radical or a conservative rejecti

Saneringseffektivitet och avfallsgenerering för sanering av radioaktivt kontaminerade urbana och rurala miljöer

Ett radioaktivt nedfall efter ett kärnkraftshaveri kan resultera i kontamination av stora landområden. I syfte att skydda människors hälsa mot joniserande strålning kan storskalig sanering vara nödvändig. Sverige saknar nationell erfarenhet av denna typ av storskalig sanering. Det finns därmed stora osäkerheter i verkan av en sådan sanering som bl.a. är beroende av de enskilda saneringsåtgärdernas

Search for a heavy charged Higgs boson decaying into a W boson and a Higgs boson in final states with leptons and b-jets in s = 13 TeV pp collisions with the ATLAS detector

This article presents a search for a heavy charged Higgs boson produced in association with a top quark and a bottom quark, and decaying into a W boson and a 125 GeV Higgs boson h. The search is performed in final states with one charged lepton, missing transverse momentum, and jets using proton-proton collision data at s = 13 TeV recorded with the ATLAS detector during Run 2 of the LHC at CERN. T

Long-Term Durability of the Sorin Soprano Aortic Bioprosthetic Valve—A Swedish Nationwide Study

Objectives Structural valve deterioration is an inherent limitation of bioprosthetic valves; however, the time it takes to develop varies depending on the valve model. The Sorin Soprano aortic bioprosthetic valve (Sorin Group/LivaNova, Milan, Italy) lacks reported long-term results. This study aims to establish the long-term durability of this bioprosthetic valve in a nationwide cohort. Methods Al

Aetiology and impact of bacterial bloodstream infections in mechanically ventilated COVID-19 patients : A prospective Swedish multicenter cohort study

Objectives Critically ill COVID-19 patients admitted to the intensive care unit (ICU) are at an increased risk of acquiring bacterial bloodstream infections (BSI). We aimed to describe patient characteristics, risk factors, and the microbiological spectrum in blood cultures and evaluate the impact of ICU-acquired BSI on outcomes in a Nordic setting. Methods A prospective multicenter cohort study w

Lika möjligheter för alla?- En studie av bristande tillgänglighet i arbetslivet

Denna uppsats behandlar diskrimineringsrättens förbud mot bristande tillgänglighet i arbetslivet och analyserar hur långt arbetsgivarens skyldighet att vidta anpassningsåtgärder för arbetstagare med funktionsnedsättning sträcker sig. Med utgångspunkt i en rättsdogmatisk metod undersöks gällande rätt genom analys av svensk diskrimineringslagstiftning, EU-rätt, internationella åtaganden enligt FN:s This thesis examines the prohibition of lack of accessibility under discrimination law in working life and analyses the extent of employers’ obligations to implement reasonable accommodation measures for employees with disabilities. Using a legal dogmatic method, the study analyses current law through Swedish discrimination legislation, EU law, international obligations under the UN Convention on