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Does aspirin protect against Alzheimer's dementia? A study in a Swedish population-based sample aged >= 80 years

Objective. It has been reported that aspirin and other non-steroidal anti-inflammatory drugs (NSAID) may protect against dementia of Alzheimer's type and/or vascular dementia. However, co-morbidity and the dose of aspirin may be critical. A major indication for low-dose aspirin is prophylaxis after stroke and transient ischaemic attacks, conditions that may obscure an anti-dementia effect by the d

Skånskt järn från malm till marknad

The iron production in the northern part of Skåne started around 1200 and ended in the 17 cent. In the medieval towns of Wä and Tommarp were smithies run by the king that took care of the tax iron and formed it into maleable and sellable forms and qualities.

p38 MAPK Signalling in Endothelial Apoptosis

Endothelial apoptosis plays an important role in atherosclerosis, and a direct proapoptotic effect of chemotherapeutics on the tumour vasculature, emphasizes the great potency of antiangiogenic therapy in the treatment of cancer. We investigated signalling pathways in endothelial apoptosis induced by the inflammatory cytokine tumour necrosis factor alpha (TNF), the main target of which is the endo

Essays on Fiscal Policy, Private Consumption and Non-Stationary Panel Data

Popular Abstract in Swedish Den kanske viktigaste anledningen till att söka en grundläggande förståelse av ekonomiskt beteende är att erhålla ett underlag för utformningen och genomförandet av ekonomisk politik. Utan en sådan förståelse minskas möjligheterna att uppnå målen för den ekonomiska politiken. Detta gäller i synnerhet den ekonomiska politik som bedrivs genom finanspolitik. En av finanspIn the first essay of this thesis, we examine whether the effects of fiscal expansions and contractions exert a symmetric influence on the relationship between fiscal policy and private consumption. Our results indicate a considerable asymmetry across fiscal expansions and contractions. More specifically, during fiscal contractions, transfers seem to influence private consumption in a neoclassical

Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients.

Background: p21-activated kinase 1 (Pak1) phosphorylates many proteins in both normal and transformed cells. Its ability to phosphorylate and thereby activate the estrogen receptor alpha (ER alpha) potentially limits the effectiveness of antiestrogen treatment in breast cancer. Here we studied associations between Pak1 expression and subcellular localization in tumor cells and tamoxifen resistance

A hemolytic assay for the estimation of functional mannose-binding lectin levels in human serum

A simple assay was developed to estimate functional mannose-binding lectin (MBL) levels in serum based on the principle of yeast-induced bystander lysis of chicken erythrocytes (ChE). The assay is sensitive to inhibition by ethylene glycol bis-(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid (EGTA) (which allows alternative pathway activation), ethylene diamine tetraacetic acid (EDTA), mannose,

Filial children and ageing parents : intergenerational family ties as politics and practice among Chinese Singaporeans

Filial Children and Ageing Parents is an anthropological study of the politics and practice of intergenerational relations among Chinese Singaporeans. Contrary to idealized notions of solid Chinese/Asian family values, this paper attempts to unfold the strains and challenges of intergenerational family relations in everyday life. In particular, it examines the issue of filial obligations between c

Expression, purification, crystallisation and preliminary X-ray diffraction analysis of Thermotoga neapolitana beta-glucosidase B

-Glucosidases belong to families 1, 3 and 9 of the glycoside hydrolases and act on cello-oligosaccharides. Family 1 and 3 enzymes are retaining and are reported to have transglycosylation activity, which can be used to produce oligosaccharides and glycoconjugates. Family 3 enzymes are less well characterized than their family 1 homologues and to date only two crystal structures have been solved. H

A New Type of Band Crossing at Large Deformation

A detailed study of the positive parity yrast and yrare rotational bands in Rb-77 is presented. Using the reaction Ca-40(Ca-40,3p) and the EUROGAM I spectrometer, gamma gamma gamma coincidences enabled us to follow both bands over a large spin range and to measure many E2 strengths. The moments of inertia and transition quadrupole moments indicate that a more deformed band (epsilon(2) approximate

Experimental approach towards shell structure at Sn-100 and Ni-78

The status of experimental approach to Sn-100 and Ni-78 is reviewed. Revised single particle energies for neutrons are deduced for the N=Z=50 shell closure and evidence for low lying I-pi=2(+) and 3(-) states is presented. Moderate E2 polarization charges of 0.1 e and 0.6 e are found to reproduce the experimental data when core excitation of Sn-100 is properly accounted for in the shell model. For

Geometric and electronic structure of PdMn bimetallic systems on Pd(100)

An experimental and theoretical study of PdMn bimetallic systems formed on Pd(100) is presented. It is shown that a flat Mn monolayer can be formed at 90 K. A comparison of calculated Mn 3d density-of-states and experimental valence photoemission and x-ray-absorption results suggests that the monolayer is antiferromagnetic, in line with earlier predictions. A similar comparison for the Pd(100)-Mn-

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Abstract in Norwegian Målet med denne studien var å utforske hvordan en kunne fortolke ekstatisk spiritualitet i et religionspsykologisk perspektiv, illustrert ved Toronto-vekkelsen. Studien er en kvalitativ studie basert på intervjuer, feltobservasjoner og skrevne dokumenter. Det teoretiske rammeverket er interdisiplinært ved at det er brukt teorier fra egopsykologi, sosialpsykologi, sosiologi, kThe purpose of this dissertation was to study how to interpret ecstatic spirituality, illustrated by the Toronto Blessing, from a religio-psycho¬logical point of view. The study is a qualitative research based on inter¬views, field observations and written documents. The theo¬retical framework is interdisciplinary, using theories from ego-psychology, social psychology, sociology, cultural anthropo

The Transient Response Technique for the Study of Hydrocarbon Oxidation on Metal Oxides: Simulation of the Responses for Various Propene Oxidation Mechanism

Partial differential equations, describing the consumption of reactants and the formation of products, have been solved numerically for a step change from inert to reactant feed considering different variants of propene oxidation mechanisms. The response features and their dependency on the rate limiting step have been rationalised in terms of conclusions, which can serve as general guidelines for

Essays on Financial Models

Popular Abstract in Swedish Alla finansiella modeller bygger på antaganden, approximationer och förenklingar. Syftet med avhandlingen är att undersöka giltigheten och rimligheten i ett antal välkända och populära finansiella och ekonometriska modeller, med en tonvikt på de svenska aktie- och optionsmarknaderna. De ekonomiska och statistiska effekterna av alltför restriktiva modellantaganden undersThis thesis consists of five essays exploring the validity of some extensively used financial models with a focus on the Swedish equity and derivative markets. The essays are of both an empirical and a theoretical nature. In the first paper, The Search for Chaos and Nonlinearities in Swedish Stock Index Returns, an investigation of the presence of nonlinearities in general and chaos in particular