The lactate dehydrogenase (LDH) activity and isoform distribution of LDH were investigated in tissue samples from the rat portal vein, aorta and urinary bladder. In addition, samples were obtained from hypertrophic urinary bladder. The total LDH activity per unit smooth muscle volume was higher in the urinary bladder compared to that in portal vein and aorta. Five LDH isoforms, reflecting differen

Cetyltrimethylammonium surfactants with a range of oligo carboxylate anions bearing. 2, 3, or 4 negative charges have been synthesized, and their respective behaviors in binary mixtures with water and in ternary mixtures with added decanol have been investigated. In binary mixtures with water, all surfactants formed nearly spherical micelles at high water contents; however, the interactions betwee

Car developers use digital human modeling tools to analyze and visualize car interiors in relation to human characteristics before the vehicles are actually constructed. Developers, reviewers and users of human simulation tools often claim that such tools can reduce development time and costs. In car industry companies today, human simulation tools are used by a single or a few experts in an infor

Objective. A refrigerator-stable formulation of ProQuad has been developed to expand the utility of ProQuad to areas in which maintenance of a frozen cold chain (- 15 degrees C or colder) during storage and transport may not be feasible. The objective of this study was to demonstrate that the immunogenicity and safety profiles of a refrigerator-stable formulation of ProQuad are similar to the rece

We apply the orthogonal portfolio approach to analyse the importance of risk factors potentially missing from the CAPM. We generalize the approach proposed by MacKinlay and Pastor (2000) [MacKinlay, A.C., Pastor, L., 2000. Asset pricing models: implications for expected returns and portfolio selection. Review of Financial Studies 13, 883–916] by estimating the Sharpe ratio of the optimal orthogona

Breast and prostate cancer preferentially metastasize in the skeleton, inducinglocally increased bone resorption by osteoclasts. Bisphosphonates (BPs), potent inhibitors of osteoclasts and bone resorption, are able to reduce metastatic bone lesions, but the metastasis-related cellular target molecules for BPs have not yet been identified. In osteoclasts, nitrogen-containing BPs inhibit the functio

In the Swedish National Care Programme for Hodgkin's lymphoma (HL) a less intensive chemotherapy regimen with individualized dosing (LVPP/OEPA) was introduced in 1989. In total, 139 patients, 77 between 1985 and 1988 and 62 between 1989 and 1992, were studied. Mean ages were 72 and 71 years, respectively. One hundred and nineteen patients were treated with curative intention, 63 (82%) between 1985

ABSTRACT. Differences in labour force participation and unemployment rates between indigenous populations and immigrants are common throughout Europe. But the gap seems to be particularly wide in Sweden. Based on studies of work places that traditionally employed large numbers of immigrants, but where they are now declining, it is argued that a driving force behind this process of exclusion is to

When plant tissue is wounded a number of protective processes start. We have made a study by isothermal calorimetry of the heat production response of root and tuber tissue to wounding. Samples with different surface to volume ratios were prepared from carrots, potatoes and swedes (rutabaga) and the thermal power was measured in closed glass ampoules in a TAM Air isothermal calorimeter. The evalua

The increase in Ca(2+)-activated force caused by polyamines in beta-escin-permeabilized guinda pig ileum is shown to be associated with increased myosin 20-kDa light chain (LC20) phosphorylation and shortening velocity. Myosin LC20 dephosphorylation with arrested kinase activity was slower in the presence of 1 mM spermine. Smooth muscle phosphatases (SMP-I, -II, -III, and -IV) isolated from turkey

The theme of this thesis is to study discretizations of nonlinear dissipative evolution equations, which arise in e.g. advection-diffusion-reaction processes. The convergence analysis is conducted by first considering an abstract time discretization of the problem, which enables a decoupling of the time and spatial approximations, and secondly by introducing the spatial discretization as an evolut