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Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets.

Genetic and epigenetic mechanisms may interact and together affect biological processes and disease development. However, most previous studies have investigated genetic and epigenetic mechanisms independently, and studies examining their interactions throughout the human genome are lacking. To identify genetic loci that interact with the epigenome, we performed the first genome-wide DNA methylati

Identification of the BCAR1-CFDP1-TMEM170A Locus as a Determinant of Carotid Intima-Media Thickness and Coronary Artery Disease Risk

Background-Carotid intima-media thickness (cIMT) is a widely accepted marker of subclinical atherosclerosis. To date, large-scale investigations of genetic determinants of cIMT are sparse. Methods and Results-To identify cIMT-associated genes and genetic variants, a discovery analysis using the Illumina 200K CardioMetabochip was conducted in 3430 subjects with detailed ultrasonographic determinati

Development Concept for Timber Truck

The project “ETT-Modular system for timber transport” investigates the possibilities of making logging shipments more effective, decrease their fuel consumption and road wear without compromising traffic safety. As part of this project a timber vehi-cle, the ETT-vehicle, that pulls four piles of timber, is 30 metres long, and has a gross combination weight of 90 tons, is tested on a distance betwe

Trajectories of academic mobility: a qualitative study from a global perspective

Background: The literature reviewed in the context of this master’ programme frequently refers to the enormous and increasing flows of people in the global era (Dicken, 2007; Lechner, 2004; Yeates, 2008); consequently, these flows have different directions and motives and represent diverse types of migration and migrants. As a result, the pivotal point here is the specificity of scientific migrati

Strategisk omorientering mot ökat kundfokus- En studie om kundkontaktcenters roll i förändringsprocessen.

Some markets represent companies that offer similar products in terms of design, quality and price. In this reality competitive advantages have to be created and developed in other ways. Many companies have therefore chosen a market oriented strategy that focuses on the client and their needs. According to studies within the field of Service management the interaction between the company and the c

Dreaming of a Red Lamborghini and Blue Sky: Towards Understanding Sustainability and Sustainable Consumption in Developing Countries.

Abstract: Title: Dreaming of a Red Lamborghini and Blue Sky: Towards Understanding Sustainability and Sustainable Consumption in Developing Countries. Date of the Seminar: 1st June, 2010 Course: BUS 808 -Master thesis in International Marketing and Brand Management. Authors: Bishaara Hameed, Igor Ackerberg, Sundus Ahad Khan Advisors: Sofia Ulver-Sneistrup Keywords: Sustainability Discourses, Susta

Relationer i dagligvaruhandeln

Abstract The food retail market of today constitutes a great number of relationships, both vis-à-vis customers as well as suppliers, which stress the importance of the retail operator to keep an attentive outlook. With this, environmental issues has raised questions to what extend retail transportation can be carried out with greater consideration to environmental aspects, which increases the pres

Begreppet verksamhetsöverlåtelse och dess tillämpning på detaljhandeln

The aim of this study is to investigate the concept of transfer of an undertaking and apply the result to in the retailing branch. The questions to be answered are: What is included in the concept of transfer of an undertaking? When is a transfer within retailing to be concidered as a transfer according to article 1.1 in the directive 2001/23/EG and in 6 b § LAS? In 1977 the directive 77/187/EG wa

Överföringar av upplysningar och bevis mellan avtalsparter

Denna uppsats handlar om särskilda problem som kan drabba parterna i en domstolsprocess på grund av att de har olika tillgång till relevant information. Det huvudsakliga föremålet för min undersökning har varit exempel på avtal som används för att komma tillrätta med ett ojämlikt informationsläge innan en process faktiskt inleds. För att ge en bakgrund till de avtalen börjar jag dock med att gå igThis essay deals with specific problems that can affect the parties in court proceedings because they have different degrees of access to relevant information. The main purpose of my investigation was to find examples of contracts used to adress unequalities in the parties’ abilities as it comes to pre-trial information collectio. I begin, however, with a rough sketch of the main features of the r

Upphovsrätt och olovlig fildelning - en analys av ansvar, intresseavvägningar och åtgärder i digital miljö

Olovligt tillgängliggörande av upphovsrättsligt skyddat material genom fildelning är ett av vår tids mest debatterade ämnen. Teknikens utveckling har gjort det möjligt för enskilda personer att snabbt och kostnadsfritt tillgodogöra sig perfekta kopior av musik och film. Detta resulterar i att kompensation uteblir för upphovsmän och deras rättighetshavare. På grund av anonymiteten på internet är deIllegitimate communication of copyrighted material to the public through file sharing is one of the most debated subjects of our time. The development of technology has made it possible for individual people to quickly and free of charge assimilate music and movies in perfect condition without any compensation being paid to the creators or other rights holders. As a result of the anonymity the int

Enhanced Biological Phosphorus Removal - Carbon Sources, Nitrate as Electron Acceptor, and Characterisation of the Sludge Community

Enhanced biological phosphorus removal (EBPR) was studied in laboratory scale experiments as well as in a full scale EBPR process. The studies were focused on carbon source transformations, the use of nitrate as an electron acceptor and characterisation of the microflora. A continuous anaerobic/aerobic laboratory system was operated on synthetic wastewater with acetate as sole carbon source. An ef

Bacterial use of allochthonous organic carbon for respiration and growth in boreal freshwater systems

Popular Abstract in English N/AAquatic systems worldwide receive large amounts of organic carbon from terrestrial sources. This ‘allochthonous’ organic carbon (AlloOC) affects critical physical and chemical properties of freshwater ecosystems, with consequences for food web structures and exchange of greenhouse gases with the atmosphere. In the boreal region, loadings of AlloOC are particularly high due to leaching from huge or

Ceylon cinnamon does not affect postprandial plasma glucose or insulin in subjects with impaired glu

Ceylon cinnamon does not affect postprandial plasma glucose or insulin in subjects with impaired glucose tolerance Ceylon cinnamon does not affect postprandial plasma glucose or insulin in subjects with impaired glucose tolerance Jennie Wickenberg¹, Sandra Lindstedt2, Kerstin Berntorp 3, Jan Nilsson4, Joanna Hlebowicz¹ 1Department of Medicine, Lund University, Malmö University Hospital, Malmö, Swe

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A new method for normalized interpretation of antimicrobial resistance from disk test results for comparative purposes.

Objective To evaluate a calibration method for disk diffusion antibiotic susceptibility tests, using zone diameter values generated in the individual laboratory as the internal calibrator for combinations of antibiotic and bacterial species. Methods The high-zone side of zone histogram distributions was first analyzed by moving averages to determine the peak position of the susceptible population