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Purpose: We investigated the distribution of cannabinoid receptor subtypes 1 and 2 in the detrusor of different species and studied the effects of cannabinoid receptor 1 and 2 agonists on bladder function. Materials and Methods: Cannabinoid receptor 1 and 2 expression was studied with Western blot and immunohistochemistry in rat, monkey and human detrusors. Co-staining was done for markers of sens
Background: Dental caries is unevenly distributed within populations with a higher burden in low socio-economy groups. Several attempts have been made to allocate resources to those that need them the most; there is a need for convenient approaches to population-based monitoring of caries risk over time. The aim of this study was to develop the geo-map concept, addressing time trends in caries ris
BACKGROUND: Although parasitism has been acknowledged as an important selective force in the evolution of host life histories, studies of fitness effects of parasites in wild populations have yielded mixed results. One reason for this may be that most studies only test for a linear relationship between infection intensity and host fitness. If resistance to parasites is costly, however, fitness may
Background: Overweight and obesity during pregnancy raise the risk of gestational diabetes and birth complications. Lifestyle factors like physical activity may decrease these risks through beneficial effects on glucose homeostasis. Here we examined physical activity patterns and their relationships with measures of glucose homeostasis in late pregnancy compared to non-pregnant women. Methods: Nor
In a population-based study on cobalamin status and incident fractures in elderly men (n = 790) with an average follow-up of 5.9 years, we found that low levels of metabolically active and total cobalamins predict incident fractures, independently of body mass index (BMI), bone mineral density (BMD), plasma total homocysteine (tHcy), and cystatin C. Cobalamin deficiency in elderlies may affect bon
OBJECTIVE: To estimate the incremental cost-effectiveness of infliximab versus conventional combination treatment over 21 months in patients with methotrexate-refractory early rheumatoid arthritis. METHODS: In this multicentre, two-arm, parallel, randomised, active-controlled, open-label trial, rheumatoid arthritis patients with <1 year symptom duration were recruited from 15 rheumatology clini
Abstract Titel: Navigating Uncertainty: Exploring mechanisms roles in changing work conditions Seminar date: 1 June 2023 Authors: Lucas Ekedahl, Oscar Steinvik, Johan Ottosson Course: FEKH99, Examensarbete i Entreprenörskap och Innovation, 15 Högskolepoäng. Supervisor: Ziad El-Awad Key word: Mechanisms, Small Business, Remote Work Contingency Theory and Crises. Thesis question: How do small busine
Fragility fractures are a major health concern and accurate estimation of bone strength is important for fracture risk assessment. Finite element (FE) models can provide reliable estimates of femoral bone strength, but traditional approaches typically require three-dimensional imaging and computationally intensive model generation. Previous research has enabled reconstruction of subject-specific F
De senaste åren har präglats av en repressiv kriminalpolitik vilket kommit till uttryck i reformer som påverkat särbehandlingen av barn och unga la-göverträdare. I juli 2023 tillsattes utredningen SOU 2025:11 Straffbarhets-åldern med uppdrag att överväga och föreslå en sänkning av straffbarhets-åldern. Utredningens arbete resulterade till en sänkning av straffbarhetsål-dern till 14 år vid allvarli
Den 1 juli 2018 ändrades våldtäktsbrottet i Sverige, så att det inte längre krävdes att den tilltalade använt våld, hot eller utnyttjande för att få målsä-gande att delta i samlaget. I stället drogs gränsen för våldtäkt vid att delta-gandet inte varit frivilligt. Frivillighet är i detta sammanhang inte samma sak som målsägandens vilja. I stället handlar det om hur offret har visat den tilltalade v
Denna uppsats analyserar hur rekvisitet ”särskilda skäl” ska tillämpas vid tvångsinlösen enligt ABL och vilka konsekvenser denna tillämpning får för tvångsinlöseninstitutets minoritetsskyddande funktion. Reglerna om tvångsin-lösen innebär att en aktieägare som innehar minst nio tiondelar av samtliga aktier kan tvinga återstående aktieägare att sälja sina aktier, samtidigt som mi-noriteten har rätt
Extreme climate events, such as heatwaves, are predicted to increase in frequency, intensity, and duration in the near future. Subarctic and boreal climate zones are expected to be especially negatively impacted, as recent shifts in temperature regimes are already particularly strong compared with more southern biomes. While many studies have focused on gradual warming and on both acute and chroni
Syftet med uppsatsen är att beskriva och analysera hur regelverket kring penningtvätt samspelar med dataskyddsrätten, särskilt i fråga om hanteringen av kunduppgifter som används för att uppfylla bankers krav på kundkännedom. Uppsatsen behandlar dels vilka skyldigheter bankerna har enligt penningtvättsregler, dels vilka krav EU:s dataskyddsbestämmelser ställer på bankernas behandling av personuppgThe purpose of this thesis is to describe and analyse how Anti-Money Laundering regulations interact with Data protection law, particularly regarding the handling of customer data used to fulfil banks’ customer due diligence requirements. The thesis examines both the obligations imposed on banks under Anti-Money Laundering rules and the requirements set by the EU’s data protection framework for th
2023 presenterades ett kommittédirektiv som tillsatte en utredning med uppdraget att se över den nuvarande särbehandlingen av unga lagöverträdare inom straffrätten och föreslå ändringar av systemet. Syftet var att höja graden av repression och minska ungdomsreduktionen. Uppsatsen fokuserar på de före-slagna förändringarna för åldersgrupperna 15–17 år samt 18–20 år. Utredningen föreslår att personeIn 2023, a committee directive was issued to initiate an investigation aimed at reviewing the current special treatment of young offenders within criminal law and proposing changes to the system. The goal was to increase the level of repression and reduce youth sentence reductions. This paper focuses on the proposed changes in the report for the age groups 15–17 and 18–20 years. The report suggest
Spruce forests cover a large portion of northern Europe, where species like Norway spruce (Picea abies) is considered to be a significant biogenic volatile organic compound (BVOC) emitter to the atmosphere. BVOCs are highly reactive and can significantly influence atmospheric chemistry. Terpenoids are the most abundant group of BVOCs where especially Monoterpenes can facilitate the formation and g
Over-frequency has become an increasingly relevant issue in the Nordic synchronous power system, mainly because of the increased number of HVDC (High Voltage Direct Current) links connecting it to neighboring synchronous systems. The aim of this thesis is to research the impact that over-frequency events, caused by faults in HVDC links, have on the Nordic power system and especially what frequenci
Artificiell intelligens (AI) har potentialen att revolutionera hälso- och sjukvår-den genom att möjliggöra tidigare och mer precisa diagnoser, individanpas-sade behandlingar och effektivare resursanvändning. Samtidigt medför AI-teknikens intåg komplexa juridiska och etiska utmaningar som måste hanteras på ett ansvarsfullt och genomtänkt sätt. Detta examensarbete analyserar dessa utmaningar, med foArtificial intelligence (AI) has the potential to revolutionize healthcare by ena-bling earlier and more accurate diagnoses, personalized treatments and more efficient use of resources. At the same time, the advent of AI technology brings with it complex legal and ethical challenges that need to be addressed in a responsible and thoughtful manner. This thesis analyzes these challenges, focusing on
With increasing environmental awareness, building materials and their impact on the environment are increasingly coming into focus. This study presents a framework for comparing Life Cycle Assessment (LCA) through A1 - A5 stages from the perspective of Global Warming Potential (GWP) to assess the climate change potential of three facade systems of different building types (villas, medium-sized bui
