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Expansion of the Ten Steps to Successful Breastfeeding into Neonatal Intensive Care: Expert Group Recommendations for Three Guiding Principles
The World Health Organization/United Nations Children's Fund Baby-Friendly Hospital Initiative: Revised, Updated, and Expanded for Integrated Care (2009) identifies the need for expanding the guidelines originally developed for maternity units to include neonatal intensive care. For this purpose, an expert group from the Nordic countries and Quebec, Canada, prepared a draft proposal, which was dis
Forecasting risk of tick-borne encephalitis (TBE): Using data from wildlife and climate to predict next year's number of human victims
Background: Over the past quarter century, the incidence of tick-borne encephalitis (TBE) has increased in most European nations. However, the number of humans stricken by the disease varies from year to year. A method for predicting major increases and decreases is needed. Methods: We assembled a 25-y database (1984-2008) of the number of human TBE victims and wildlife and climate data for the St
Isolated hepatic perfusion as a treatment for uveal melanoma liver metastases (the SCANDIUM trial): study protocol for a randomized controlled trial
Background: Uveal melanoma is the most common primary intraocular malignancy in adults. Despite successful control of the primary tumor, metastatic disease will ultimately develop in approximately 50% of patients, with the liver being the most common site for metastases. The median survival for patients with liver metastases is between 6 and 12 months, and no treatment has in randomized trials eve
Causes of death in patients with extranodal cancer of unknown primary: searching for the primary site
Age- and gender-specific mortality rates in childhood hypertrophic cardiomyopathy
Aims Hypertrophic cardiomyopathy (HCM) is the commonest inherited cause of sudden cardiac death in children; current guidelines suggest HCM screening after 12-15 years of age. The study aims to establish the age range at highest risk. Methods and results Cohort study from six regional centres of paediatric cardiology, including children presenting with sudden death; n = 150 (59% = male; 39% famili
Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease.
Chronic obstructive pulmonary disease (COPD) independently associates with an increased risk of coronary artery disease (CAD), but it has not been fully investigated whether this co-morbidity involves shared pathophysiological mechanisms. To identify potential common pathways across the two diseases, we tested all recently published single nucleotide polymorphisms (SNPs) associated with human lung
Growth of ectomycorrhizal fungal mycelium along a Norway spruce forest nitrogen deposition gradient and its effect on nitrogen leakage
Almost all boreal and temperate forest tree species live in symbiosis with ectomycorrhizal fungi (EMF); the trees transfer carbon (C) to the fungi in exchange for nutrients and water. Several studies have shown that experimental application of inorganic nitrogen (N) represses production of EMF extramatrical mycelia (EMM), but studies along N deposition gradients are underrepresented. Other environ
TuFT: Tunnel Fire Tools - Teknisk dokumentation
Inom ramen för det svenska forskningsprojektet Taktik och metodik vid brand i undermarksanläggningar har ett enkelt planeringsverktyg utvecklats som bl a erbjuder stöd till beslutsfattare involverade i planeringen av räddningsinsatser i väg- och järnvägstunnlar. Verktyget, som har utvecklats vid Lunds universitet, heter TuFT och är en förkortning av Tunnel Fire Tools. TuFT kan beskrivas som ett my
Does migratory distance affect fuelling in a medium-distance passerine migrant?: results from direct and step-wise simulated magnetic displacements.
In birds, fat accumulation before and during migration has been shown to be endogenously controlled and tuned by, among other factors, the Earth's magnetic field. However, our knowledge about the influence of the geomagnetic field on the fuelling in migrating birds is still limited to just a few nocturnally migrating passerine species. In order to study if variations of the magnetic field can also
Validation and Verification of Fire Models for Fire Safety Engineering
The move towards fire performance-based design in building and transport regulations has led to an increased use of fire models. This increased use of these models and the evolution of different regulations have put higher demands on the predictive capability of fire models. The purpose of this paper is to give an overview of different activities relating to the validation and verification of comp
Surveillance and File-Sharing: Two Issues Engaging the Unengaged
Abstract in UndeterminedOver the last decade a great deal of research attention has been paid to the Internet as a potential vehicle for civic and/or political engagement among young people. Many of these analyses have been looking (or perhaps hoping) for a simple cause-and-effect relationship. Young people seem uninterested in traditional forms of politics, but they are very interested in Interne
2-Aminoadipic acid is a biomarker for diabetes risk
Improvements in metabolite-profiling techniques are providing increased breadth of coverage of the human metabolome and may highlight biomarkers and pathways in common diseases such as diabetes. Using a metabolomics platform that analyzes intermediary organic acids, purines, pyrimidines, and other compounds, we performed a nested case-control study of 188 individuals who developed diabetes and 188
The effect of achieving a systolic blood pressure of 140 mmHg. A prospective study of ambulatory measurements in type 2 diabetic patients with nephropathy
Population fluctuations and synchrony of grassland butterflies in relation to species traits.
Population fluctuations and synchrony influence population persistence; species with larger fluctuations and more synchronised population fluctuations face higher extinction risks. Here, we analyse the effect of diet specialisation, mobility, length of the flight period, and distance to the northern edge of the species' distribution in relation to between-year population fluctuations and synchrony
TCF7L2 Polymorphism, Weight Loss and Proinsulin: Insulin Ratio in the Diabetes Prevention Program
Aims: TCF7L2 variants have been associated with type 2 diabetes, body mass index (BMI), and deficits in proinsulin processing and insulin secretion. Here we sought to test whether these effects were apparent in high-risk individuals and modify treatment responses. Methods: We examined the potential role of the TCF7L2 rs7903146 variant in predicting resistance to weight loss or a lack of improvemen
Harnessing Handheld Computing - Framework, Toolkit and Design Propositions
The rapid development of handheld technologies such as smartphones and personal digital assistants in recent years has created opportunities for the mobile workforce to take advantage of computerised information systems. To apprehend and harness the opportunities of computerised information systems implemented on handheld devices it is crucial to fully understand the user group and the handheld te
Brain natriuretic peptide is related to diastolic dysfunction whereas urinary albumin excretion rate is related to left ventricular mass in asymptomatic type 2 diabetes patients
Background: The aims of this study were to estimate the prevalence of left ventricular systolic (LVSD) and diastolic (LVDD) dysfunction, and to test if BNP and urinary albumin excretion rate (AER) are related to LVSD, LVD and left ventricular mass (LVM) in asymptomatic type 2 diabetes patients. Methods: Presence of LVSD, LVDD and LVM, determined with echocardiography, was related to levels of BNP
Microphthalmia transcription factor regulates pancreatic β-cell function
Precise regulation of β-cell function is crucial for maintaining blood glucose homeostasis. Pax6 is an essential regulator of β-cell-specific factors like insulin and Glut2. Studies in the developing eye suggest that Pax6 interacts with Mitf to regulate pigment cell differentiation. Here, we show that Mitf, like Pax6, is expressed in all pancreatic endocrine cells during mouse postnatal developmen
Techno-economic evaluation of stillage treatment with anaerobic digestion in a softwood-to-ethanol process.
ABSTRACT: BACKGROUND: Replacing the energy-intensive evaporation of stillage by anaerobic digestion is one way of decreasing the energy demand of the lignocellulosic biomass to the ethanol process. The biogas can be upgraded and sold as transportation fuel, injected directly into the gas grid or be incinerated on-site for combined heat and power generation. A techno-economic evaluation of the spru
