Genome-wide association studies have identified >50 common variants associated with kidney function, but these variants do not fully explain the variation in eGFR. We performed a two-stage meta-analysis of associations between genotypes from the Illumina exome array and eGFR on the basis of serum creatinine (eGFRcrea) among participants of European ancestry from the CKDGen Consortium (nStage1: 111

The study of residences at central places from the Late Iron Age in Scandinavia has mainly been aimed at identifying buildings of exceptional size or function. However, until recently the archaeological situation has not been detailed enough to study the sequence of a residence for several centuries and with internal changes related to internal or external factors. New excavation results from Uppå

Teachers’ perception of organizational communication was assessed with a tailored questionnaire sampling 401 primary and lower secondary school teachers from two municipalities in Sweden (response rate 61 %). Overall, the teachers were satisfied with the workplace communication climate, the communication structure, and collegial communication, while time for communication, was reported deficient.

Artistic research—research carried out by artists, through artistic practice—displays the markers of a burgeoning academic discipline. Dominant perspectives on research cultures would therefore predict that practitioners’ boundary work would play a decisive role in the development of this field. But when binary understandings come up against multiplex meanings, when and how do binaries matter? Foc

During inflammation, cellular glucose uptake and glycolysis are upregulated to meet an increased energy demand. For example, keratinocyte glycolysis is essential for progression of psoriasis. Therefore, understanding the regulation of glucose metabolism in keratinocytes is of importance. Here, we show that the pro-inflammatory cytokines IFNγ and TNF together rapidly induce glucose uptake, glycolys

Differential expression of microRNAs (miRNAs) is observed in many diseases including type 2 diabetes (T2D). Insulin secretion from pancreatic beta cells is central for the regulation of blood glucose levels and failure to release enough insulin results in hyperglycemia and T2D. The importance in T2D pathogenesis of single miRNAs in beta cells has been described; however, to get the full picture, h

Advanced maternal age at birth is considered a risk factor for adverse birth outcomes. A recent study applying a sibling design has shown, however, that the association might be confounded by unobserved maternal characteristics. Methods: Using total population register data on all live singleton births during the period 1999-2012 in Denmark (N = 580-133; 90% population coverage), Norway (N = 540-8

Aim To evaluate whether Long-term treatment with a fixed tow dose of warfarin in combination with aspirin improves the prognosis compared with aspirin treatment alone after an acute myocardial infarction (AMI). Methods Patients who were hospitalized for AMI were randomized to either 1.25 mg of warfarin plus 75 mg of aspirin (n=1659) daily or 75 mg of aspirin atone (n=1641). The study was performed