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Peripheral leucocyte count variations in rectal cancer treatment.

AIM: Mortality after curative surgery for rectal cancer is increased if surgery is not performed within a week of completed short course radiotherapy. A link to the suppression of leucocytes after neoadjuvant radiotherapy has been suggested. This study investigates the effects of radiotherapy on peripheral leucocyte counts, complications and survival. METHOD: Patient data variables from a retrospe

Predicted fire behaviour of steels and concrete structures

Analytical modelling has opened the door for fire behaviour prediction of not only building materials as concrete and steel but akso of quite complicated concrete structures in general. This paper reflects some of the progress made within the field. A behaviour model of steel is used for coupling results from steady state and transient sate tests. A recently developed procedure is shown on how to

Epidemiology and etiology of childhood fractures in southern Sweden

Background: As much as 40–50% of children are expected to sustain fractures during growth. A childhood fracture is alsoassociated with high risk of fractures in adult life. Previous research has shown that fracture incidence has not been stable andsome studies suggest that this has also continued during recent decades.Aims: The aim of this thesis was therefore to describe fracture epidemiology and

Evaluating Evaluations of Innovation Policy: Exploring Reliability, Methods, and Conflicts of Interest

Expansions of innovation policies have been paralleled with an increase in the evaluations of such policies. Yet, there are few systematic evaluations of how such evaluations are conducted, by whom, and their overall conclusions. We analyze 110 evaluations of innovation policy in Sweden from 2005 to 2019. Our findings show that the majority of these evaluations are positive, about one-third are ne

Millora 2.0: Redovisning av resultat för 2018–2020

Based on repeated surveys of the vascular plant flora in 120 hectar plots in the province of Scania, southern-most Sweden, and analyses based on species-specific traits and ecological indicator values, it is concluded that significant changes have taken place 2018–2020 but that they probably mostly reflect the effects of the extremely dry and hot summer of 2018. Species richness has increased sign

Complex Scheduling with Potts Neural Networks

In a recent paper (Gislén et al. 1989) a convenient encoding and an efficient mean field algorithm for solving scheduling problems using a Potts neural network was developed and numerically explored on simplified and synthetic problems. In this work the approach is extended to realistic applications both with respect to problem complexity and size. This extension requires among other things the in

An UPLC-MS/MS assay to measure glutathione as marker for oxidative stress in cultured cells

Oxidative stress plays a role in the onset and progression of a number of diseases, such as Alzheimer’s disease, diabetes and cancer, as well as ageing. Oxidative stress is caused by an increased production of reactive oxygen species and reduced antioxidant activity, resulting in the oxidation of glutathione. The ratio of reduced to oxidised glutathione is often used as a marker of the redox state

Amino acids and the changing face of the α-cell

Glucagon has long been defined by its glucogenic action and as a result α-cells have been characterised based largely on their interaction with glucose. Recent findings have challenged this preconception, bringing to the fore the significant role glucagon plays in amino acid breakdown and underlining the importance of amino acids in glucagon secretion. The challenge that remains is defining the me

Smoking impacts endogenous estradiol and testosterone levels in young healthy women

Introduction: The purpose of the study was to elucidate the association between smoking and estradiol (E2) and testosterone (T) levels in young healthy women from highrisk families. Cigarette smoke contains multiple carcinogens and is considered a risk factor for breast cancer. However, tobacco also contains aromatase inhibiting substances, but the impact on hormonal levels in young women at the a

Opening Hours Decision and Competition in the Motor Vehicle Inspection Market

This paper examines the effect of competition on a firm's choice of opening hours in the motor vehicle inspection market. Competition affects the incentive inspection firms face when choosing opening hours, which influences the probability that consumers find service time that best matches their preferred time. We use 2SLS analyses to resolve the potential endogeneity of market entry decisions. Us

Knowledge externalities and firm heterogeneity: Effects on high and low growth firms

Knowledge externalities affect high and low growth firms differently. This paper develops two theoretical arguments. The knowledge equilibrium argument postulates that knowledge externalities weaken high growth firms for the benefit of low growth firms until performance differences vanish. The knowledge competition argument proposes that high growth firms are better positioned to identify, attract