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On the feasibility of general meanings in prepositional semantics

The paper investigates the status of general meanings in prepositional semantics. On the basis of a review of the strategies employed in different accounts of prepositions, the paper argues that strict adherence to the notion of general meanings is unfeasible in the field, partly because a purely deductive method of description breaks down as the number of possible oppositions increases. This fail

Therapeutic S100A8/A9 blockade inhibits myocardial and systemic inflammation and mitigates sepsis-induced myocardial dysfunction

Background and Aims: The triggering factors of sepsis-induced myocardial dysfunction (SIMD) are poorly understood and are not addressed by current treatments. S100A8/A9 is a pro-inflammatory alarmin abundantly secreted by activated neutrophils during infection and inflammation. We investigated the efficacy of S100A8/A9 blockade as a potential new treatment in SIMD. Methods: The relationship betwee

Qdenga® - A promising dengue fever vaccine; can it be recommended to non-immune travelers?

Qdenga® has been approved by the European Medicines Agency (EMA) for individuals > 4 years of age and for use according to national recommendations. The vaccine shows high efficacy against virologically confirmed dengue and severe dengue in clinical studies on 4–16-year old's living in endemic areas. For individuals 16–60 years old only serological data exists and there is no data for individuals

Pacemaker implantation following tricuspid valve annuloplasty: A SWEDEHEART study

ObjectiveTricuspid annuloplasty is associated with increased risk of atrioventricular block and subsequent implantation of a permanent pacemaker. However, the exact incidence of permanent pacemaker, associated risk factors, and outcomes in this frame remain debated. The aim of the study was to report permanent pacemaker incidence, risk factors, and outcomes after tricuspid annuloplasty from nation

Consensus statement on the definition of orthostatic hypertension endorsed by the American Autonomic Society and the Japanese Society of Hypertension

We propose a consensus definition of "an exaggerated orthostatic pressor response" in subjects in whom systolic blood pressure increases ≥20 mmHg when going from the supine to standing posture. This definition can be extended for seated to standing measurements. We reserve the term "orthostatic hypertension" if this pressor response leads to an upright systolic blood pressure ≥140 mmHg. We believe

Starch intake, amylase gene copy number variation, plasma proteins, and risk of cardiovascular disease and mortality

BACKGROUND: Salivary amylase, encoded by the AMY1 gene, initiate the digestion of starch. Whether starch intake or AMY1 copy number is related to disease risk is currently rather unknown. The aim was to investigate the association between starch intake and AMY1 copy number and risk of cardiovascular disease (CVD) and mortality and whether there is an interaction. In addition, we aim to identify CV

Cystatin C–Based Equation to Estimate GFR without the Inclusion of Race and Sex

BACKGROUNDThe accuracy of estimation of kidney function with the use of routine metabolic tests, such as measurement of the serum creatinine level, has been controversial. The European Kidney Function Consortium (EKFC) developed a creatinine-based equation (EKFC eGFRcr) to estimate the glomerular filtration rate (GFR) with a rescaled serum creatinine level (i.e., the serum creatinine level is divi

No Difference in Conversion Rate to Hip Arthroplasty After Intramedullary Nail or Sliding Hip Screw for Extracapsular Hip Fractures : An Observational Cohort Study of 19,604 Individuals

BACKGROUND: The widespread use of intramedullary nails (IMNs) compared with sliding hip screws (SHSs) in extracapsular hip fractures (AO/OTA 31-A1, 31-A2, 31-A3) has been questioned because of a higher complication rate, although the outcome might have improved through more recent implant designs and the learning curve. This study aimed to investigate if there is a difference with regard to the cu

Evalutation of two commercial deep learning OAR segmentation models for prostate cancer treatment

Purpose or ObjectiveTo evaluate two commercial, CE labeled deep learning-based models for automatic organs at risk segmentation on planning CT images for prostate cancer radiotherapy. Model evaluation was focused on assessing both geometrical metrics and evaluating a potential time saving.Material and MethodsThe evaluated models consisted of RayStation 10B Deep Learning Segmentation (RaySearch Lab

Litterär kvinnokamp, anno 2014 : Feminismens funktioner i receptionen av Kristina Sandbergs Maj-trilogi

This article examines the functions of feminism in the critical reception of Kristina Sandberg’s Maj-Trilogy, published 2010-2014. Detailing the evaluative patterns of reviews, it is shown that critics’ increased attention to feminist politics and women’s history in the novels was tied to a de-aestheticizing rhetoric, exemplifying gender hierarchies on the literary field. However, the trilogy’s cr

Psychometric evaluation of the electronic faces thermometer scale for pain assessment in children 8–17 years old: A study protocol

It is often a challenge for a child to communicate their pain, and their possibilities to do so should be strengthened in healthcare settings. Digital self-assessment provides a potential solution for person-centered care in pain management and promotes child participation when a child is ill. A child's perception of pain assessment differs when it is assessed using digital or analog formats. As w

The evolution of lexical semantics dynamics, directionality, and drift

Introduction: The directionality of semantic change is problematic in traditional comparative models of language reconstruction. Compared to, e.g., phonological and morphological change, the directions of meaning change over time are potentially endless and difficult to reconstruct. The current paper attempts to reconstruct the mechanisms of lexical meaning change by a quantitative model. We use a

Konformitetsprincipens gränsmarker - Med inriktning mot unga lagöverträdare och en sänkning av straffmyndighetsåldern

Konformitetsprincipen är den grundläggande rättsprincipen i den straffrätts-liga ansvarsläran som ger besked om att den som inte hade förmåga eller tillfälle att kunna rätta sig efter lagen inte bör bli straffrättsligt ansvarig för ett brott. Detta eftersom ett straffansvar i den situationen hade varit orätt-färdigt och meningslöst. Den som inte kunde rå för sin brottsliga gärning ska således inte