Islet amyloid polypeptide (IAPP) is a beta cell hormone secreted together with insulin upon glucose stimulation. IAPP participates in normal glucose regulation, but IAPP is also known for its ability to misfold and form islet amyloid. Amyloid fibrils form through smaller cell toxic intermediates and deposited amyloid disrupts normal islet architecture. Even though IAPP and amyloid formation are mu

Knowledge of effects of moisture exposure on timber structures is important for serviceability and load bearing capacity of timber elements and systems. Varying climate affects the moisture content profiles in timber as the relative humidity changes in the ambient air. This paper presents methods for calculation of diffusion based moisture transport and corresponding results on how timber responds

The Social Services Acts’ Value System – An Analyze of its Practical Meaning in Social Investigations on Children This article discusses the relation between legal and practical norms, on the basis of a model over the norms main components. The focus is on the norms value component, and the question is how the value of a legal norm is implemented in that practice which the norm is aimed to regula

A study of the ambitions of the managers at AB Robertsfors Bruk and their impact on courses of action in the development of wage policy and social arrangements in the community of Robertsfors during the period 1925-35.This study deals with employer actions during a period of both internal and external change to the organization. The main focus is in the areas of wage policy and social arrangements

The present article is part of a larger project investigating the various types of linguistic change that affected and might affect the word class traditionally known under the label of interjection. The results of our research, as outlined here, concern the inter-linguistic mobility of units, i.e., borrowings, which in the source language can be (but not necessarily) interjections, and which are

This essay first outlines a philosophical theory of concepts and then applies it to two areas of relevance to psychiatrists, especially forensic psychiatrists. In the philosophical theory, the respective roles of verbal and non-verbal definitions are illuminated, and the importance of the phenomenon of division of semantic labour is stressed. It is pointed out that vagueness and ambiguity of a ter

Inflammatory diseases and inflammatory markers secreted by the liver, including C-reactive protein (CRP) and ceruloplasmin, have been associated with incident atrial fibrillation (AF). Genetic studies have not supported a causal relationship between CRP and AF, but the relationship between ceruloplasmin and AF has not been studied. The purpose of this Mendelian randomization study was to explore w

Previous research has shown that firms identified as derivative users tend to be valued at a premium relative to non-users. In this paper I develop the hypothesis that the derivative premium' is higher in firms with centralised FX exposure management, compared to a decentralised approach in which subsidiaries retain bank contacts and/or decision-making authority. This study benefits from unique su

When production is outsourced consumers possibilities to inform themselves about production processes is reduced. Information instruments for consumers, e.g. labelling, are more difficult to apply when materials and chemicals used during production cannot be monitored easily. The globalisation of production and consumption is a challenge for consumers as regards quality of products. This paper us

Product design, packaging and logistics have a significant impact on the efficiency and effectiveness of supply chains. The packaging design is usually limited by the product characteristics hence influencing possible logistical solutions. A need has been recognized to consider packaging and logistical issues early in the product development process. Case studies involving companies from the Swedi