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A randomized controlled trial of haemoglobin normalization with epoetin alfa in pre-dialysis and dialysis patients

Background. Partial correction of renal anaemia with erythropoietin improves quality of life (QoL). We aimed to examine if normalization of haemoglobin with epoetin alfa in pre-dialysis and dialysis patients further improves QoL and is safe. Methods. 416 Scandinavian patients with renal anaemia [pre-dialysis, haemodialysis (HD) and peritoneal dialysis patients] were randomized to reach a normal ha

Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research.

A wealth of biospecimen samples are stored in modern globally distributed biobanks. Biomedical researchers worldwide need to be able to combine the available resources to improve the power of large-scale studies. A prerequisite for this effort is to be able to search and access phenotypic, clinical and other information about samples that are currently stored at biobanks in an integrated manner. H

Health-related quality of life is impaired in active collagenous colitis

Objectives: The characteristic clinical symptoms of collagenous colitis are non-bloody diarrhoea, urgency and abdominal pain. Treatment is aimed at reducing the symptom burden and the disease impact on patients' health-related quality of life. The objective of this study was to analyse health-related quality of life in patients with collagenous colitis. Methods: In a cross-sectional, postal HRQL s

Intake levels of dietary long-chain PUFAs modify the association between genetic variation in FADS and LDL-C

Polymorphisms of the FA desaturase (FADS) gene cluster have been associated with LDL, HDL, and triglyceride concentrations. Because FADS converts alpha-linolenic acid (ALA) and linoleic acid into PUFAs, we investigated the interaction between different PUFA intakes and the FADS polymorphism rs174547 (T>C) on fasting blood lipid and lipoprotein concentrations. We included 4,635 individuals (60% fem

Equal access to health care may diminish the differences in outcome between native and immigrant patients with type 1 diabetes

Background/Objective: Previous studies have found that ethnicity influences glycemic control. We hypothesized that differences between Nordic and non-Nordic patients are less pronounced for children with type 1 diabetes in high incidence countries in Northern Europe. Research design and methods: We investigated patients aged 0-15 yr in national pediatric registers in Denmark (D), Iceland (I), Norw

Elites, networks and the Finnish connection in Birka

In research on Birka strong focus has since long been directed towards long-distance contacts with Western as well with and Northeastern Europe (todays Russia, Belarus and Ukraine). The great attention paid to west- and east European contacts has likely contributed to that contacts with Finland have fallen out of the discussions. However as seen from studies of the pottery in Birka the Baltic Finn

Clinical course and prognosis of never-smokers with severe alpha-1-antitrypsin deficiency (PiZZ).

BACKGROUND: Previous studies of non-smoking individuals with severe alpha-1-antitrypsin deficiency (PiZZ) have been sparse and included only a limited number of individuals, mostly identified by respiratory symptoms. The aim of this study was to estimate the prognosis of non-smoking PiZZ individuals and to analyze the most common causes of death by including a large number of individuals who had b

Vart tog behaviorismen vägen? : Social responsivitet mellan barn och vuxen, hund och människa.

This thesis studies how humans and other social responsive animals can meet and get together as companion species and what role radical behaviorist B F Skinner’s learning theory and operant conditioning possibly can play in this. Drawing from theories of discourse and discourse analysis, social responsivity and companion species, the thesis analyzes what happens with Skinner’s learning theory when

Healthcare, health and inequality in health in the Nordic countries

All five Nordic countries emphasize equal and easy access to healthcare, assuming that increased access to healthcare leads to increased health. It is the purpose of the present study to explore to which extent the populations of these countries have reached good health and a high degree of socio-economic equality in health. Each of the five countries has established extensive public health progra

Omvänd skattskyldighet - En ”quick fix” för mervärdesskattebedrägerier?

Varje år förlorar den Europeiska unionens medlemmar hundratals miljarder kronor i uteblivna mervärdesskatteintäkter. En stor del av dessa förluster beror på omfattande bedrägerier som utnyttjar de lagar och regler som gäller för unionsintern handel mel-lan EU:s medlemsstater. En särskild typ av sådana bedrägerier är Missing Trader Intra Community – fraud, MTIC-bedrägerier. Denna uppsats undersöker

Upphovsrättens digitala gränsland - En undersökning om AI-genererade alsters upphovsrättsliga skydd.

Den traditionella upphovsrätten möter utmaningar i samband med intåget av artificiell intelligens (AI) som en aktör på den kreativa marknaden. Bara ett knapptryck bort finns idag enorma kreativa möjligheter, vilket gör det möjligt för vem som helst att bli en enastående konstnär. Det nuvarande upphovsrättsliga regelverket saknar dock uttryckliga riktlinjer för hantering av AI-genererade verk. Det

"The Limits of Nudging": A Case Study on Nudge-based Interventions in E-commerce Sustainability

Modern consumerism and overconsumption in e-commerce have profound ecological ramifications, necessitating the adoption of pro-environmental behavior. Imagine a world where sustainable choices are seamlessly integrated into our online shopping experience. Nudging is a powerful tool that holds the key to transforming consumer behavior and promoting sustainable online shopping. However, there is a c

Elektrifiering av vägtrafik - Tre fallstudier i Malmö

Elbilars utveckling går fort framåt och fler väljer att investera i en. Vilka olika laddningstekniker finns det? Hur kommer laddningen av elbilar påverka våra elnät? Kraftdistribution till en elvägssträcka modelleras för att påvisa kapacitetskrav och kostnader. Studien visar även hur hemmaladdning och arbetsplatsladdning kan påverka belastningen i elnätet om reglering uteblir.