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One of the great challenges in breast cancer treatment today is to customize adjuvant treatment to each patient’s individual needs. To do this it is necessary to learn more about the prognostic and treatment predictive factors that determine the risk of relapse and response to a certain mode of treatment. This thesis describes studies on the effect of amplified in breast cancer 1 (AIB1), a coactiv

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Earlier studies have indicated that the fat mass and obesity-associated gene (FTO) is not only associated with BMI and weight but also with appetite and dietary intake.

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The principal aim of the thesis is to evaluate the significance of the documentation of a building’s history for the work of restoring it and caring for it. Thus it may be said to address restoration as a hermeneutical problem, besides considering the relationships between the work of documentation; analyses of the resulting data; and the creative process in which the ideology of restoration is im

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Boken innehåller en grekisk text (baserad på cod. Athos Protaton 86) utgiven av Britt Dahlman och en svensk översättning av den systematiska samlingen av Apophthegmata Patrum (Ökenfädernas tänkespråk), bok 6. Översättningen har gjorts gemensamt av deltagarna i översättningsseminariet vid Johannesakademin.

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The Fountain House Movement – or the Clubhouse Movement - is an organization for community support, meeting the needs of adults suffering from mental illness. It was founded by a self-help group among discharged patients in New York in the 1940s. Today there are more than 300 clubhouses around the world. The aim of this dissertation is to characterize, interpret and understand the Clubhouse Moveme

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Type 2 Diabetes (T2D) is characterized by dysregulated beta-and alpha-cell hormone secretion leading to elevated blood glucose levels. Several proteins are crucial in maintaining exocytosis of the hormone-containing granules such as Syntaxin1A (Stx1A), SNAP25, Munc-18 (Stxbp1) and the family of Synaptotagmins (Syts). The aim of this thesis has been to investigate functional and genetic events that

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Boken innehåller en grekisk text (baserad på cod. Parisinus graecus 2474) utgiven av Britt Dahlman och en svensk översättning av den systematiska samlingen av Apophthegmata Patrum (Ökenfädernas tänkespråk), bok 4. Översättningen har gjorts gemensamt av deltagarna i översättningsseminariet vid Johannesakademin.

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This dissertation consists of four sections. Section 1 deals with a presentation of a model for Intensive Family Therapy (IFT) and of the units practising this model. References to research in the field of Family Therapy as well as to relevant theories are made. A theoretical model for describing the functioning of these units is presented. Measuring instruments were developed on the basis of this

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Abstract Aims: The aim of this thesis was to investigate how the impact of Parkinson’s disease, a chronic neurodegenerative disorder, influences the person’s health-related quality of life. The aim was also to investigate nursing assessment and management of Parkinson’s in elderly persons. Methods: The study started in1998, one year later a follow-up was conducted. The sample contained in the fir

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Boken innehåller en grekisk text (baserad på cod. Athos Protaton 86) utgiven av Britt Dahlman och en svensk översättning av den systematiska samlingen av Apophthegmata Patrum (Ökenfädernas tänkespråk), bok 5. Översättningen har gjorts gemensamt av deltagarna i översättningsseminariet vid Johannesakademin.