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What is the relation between the words in language and our everyday actions? Are linguistic structures dependent on our actions, or does language function on its own? This thesis deals with the pragmatic foundations of language and proposes a model of meaning in language that is based on our expectations about the world and about other people. On this view, language is seen as composed of three f
Fine airborne particles are associated with adverse health effects in the human population. The aim of this research was to develop and evaluate methods for in-situ characterisation of fine and ultrafine particles and to determine their deposition in the human airways. The aim was also to increase knowledge about health and environmentally relevant properties of aerosols from biomass combustion an
Photodynamic therapy (PDT) as a cancer treatment modality relies on the simultaneous presence of three components; light, photosensitiser and oxygen. Once excited by the light, the photosensitiser can interact with oxygen, leading to the formation of toxic oxygen species. These reactive substances induce cellular damage within the irradiated tissue volume. PDT has been investigated for treating ma
The goal in this thesis is development of gene therapy for malignant infantile osteopetrosis (IMO), a rare but severe genetic bone disease. The concept of osteopetrosis implies dysfunction or lack of osteoclasts, the bone resorbing cells in our body, resulting in failure of normal bone breakdown. Although involved in bone remodeling, osteoclasts are of hematopoietic origin and may potentially be t
The standard 12-lead electrocardiogram (ECG) is one of the most commonly used methods for diagnosing heart disease. Standard ECG is not always optimal, however, and new ECG methods can provide additional information. Analysis of high-frequency QRS components (HF-QRS) has been shown to increase the diagnostic performance of the ECG. Since the amplitudes of the HF-QRS are low compared with those vis
The main aim of this work, was to lay the foundations for the experimental realisation of a quantum mechanical controlled NOT gate in rare-earth-metal-ion-doped crystals. Small amounts of rare-earth elements, added during the growth of some inorganic crystals, will become substituted into the crystal lattice as trivalent ions. The trivalent rare-earth-metal ions between cerium, with atomic number
Asthma is a chronic disorder of the lower airways, characterized by inflammation and hyperreactivity. Pro-inflammatory cytokines like tumour necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) are known to play important roles in the pathogenesis, but our knowledge how these cytokines contribute to the development of airway hyperreactivity is limited. The aims of the present study
This paper explores how marketing is conducted in for-profit social ventures. Knowledge regarding the for-profit social context is considered rather limited given that it has been largely marginalized by being associated either to the fully for-profit or solely non-profit extremes. In that respect, much of the existing literature has not to acknowledge the unique challenges that a dual mission, su
Development is a contentious concept, praised by some for enabling progress and criticised by others for perpetuating global power imbalances. Development assistance tends to strengthen the donor-recipient dependency, which, according to critics, primarily serves the interests of the Global North while neglecting the needs of the Global South. Mainstream market-driven strategies have exacerbated i
Märta Måås-Fjetterström’s textile career was largely based on a collective effort. As a textile artist in her own workshop, she drew patterns that she let employed weavers weave. Together with a few other artists, she helped elevate the craft – the carpet – to the realm of art, by signing her works early on. After Märta Måås-Fjetterström’s death, Barbro Nilsson took over the role as artistic direc
Extreme heat and heatwaves constitute a growing challenge för municipal planning in relation to climate change. The aim of this study is to examine how risks related to extreme heat are addressed in the comprehensive planning of Malmö, Landskrona and Hässleholm, and also see how these approaches can be understood in relation to urban resilience and the PCCC framework created by Jabareen (2015) - P
Cerebral visual impairment (CVI) is a brain-based neurodevelopmental disorder of visual processing caused by early injury to visual pathways and cortical areas. Visual processing relies on two anatomically and functionally distinct pathways originating in the primary visual cortex (V1): the dorsal ("where") stream, which processes spatial location, and the ventral ("what") stre
Introduction/Background: Measurement of umbilical cord blood gasesat birth is the gold standard of capturing the metabolic state of the newborn. Dual sampling of umbilical cord vessels is mandatory, yet the longterm predictive value of venoarterial differences, ΔpH, remain undetermined. Previously, large ΔpH showed a protective effect against adverseneonatal outcomes.Objectives: To investigate the
