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Protein Complexity via Non-Native States: Binding, Stability, and Structural Studies of Calbindin D9k and HAMLET (Human alpha-lactalbumin Made LEthal to Tumor cells).

Using optical spectroscopy, nuclear magnetic resonance (NMR), and differential scanning Calorimetry (DSC), I have studied two different calcium binding proteins that can form kinetically trapped altered states. Calcium is very important in numerous biological processes such as blood coagulation, signal transduction, muscle contraction and bone formation. Calcium binding to proteins regulates these

Toward Creating a Coherent, Next-Generation Light Source with special emphasis on nonlinear harmonic generation in single-pass, high-gain free-electron lasers

There is a strong desire for short wavelength (~1 Å), short pulsewidth (<100 fs), high-brightness, transverse and longitudinally coherent light pulses for use by the synchrotron radiation community. These requirements exceed the limits achievable by existing, so-called, "third-generation" light sources, such as the Advanced Photon Source (APS) at Argonne National Laboratory (ANL), USA, the Europea

Traffic analysis in the TRAMMS project

Internet usage is evolving, from the traditional WWW usage (i.e. downloading web pages), to triple-play usage where households may have all their communication services (telephony, data, TV) through their broadband access connection. The challenge is to design IP access networks so that they can deliver services with strict QoS demands such as IPTV at the same time as having capacity for (from the

Tidsmässig eventutveckling

Problematisering: Event som fenomen har under de senaste decennierna fått stor genomslagskraft och har kommit att bli ett populärt forum för skapande av nya tjänsterelationer och affärsmöjligheter. Forskningen kring event ur ett utvecklingsperspektiv är knapp. Vi ser därmed en möjlighet i att bidra med förbättrad kunskap kring tidsmässig eventutveckling genom att plocka in ett tjänsteutvecklingspe

Chaebolföretagen - en "omöjlig" konfiguration i den sydkoreanska industrialiseringsprocessen.

The chaebol conglomerates, which constituted the backbone of the "South Korean miracle", became the instrument for economic growth within a framework laid down by the "developmental state". With a minimum of own capital, but with private owner-control and loan-financing, these chaebols were able to expand. How could this "impossible" configuration survive? The thesis analyses how this could contin

Peacemaking through Friendships: Ambivalent Anglican Discourses in Jerusalem 1920-1948

During the British Mandate period in Palestine, Jewish, Muslim and Christian chidren studied together at Anglican missionary schools. This educational project became part of wider efforts made by the Anglican Church to promote peace in Palestine. The article focuses on statements on 'friendship' made by the Anglican bishops in Jerusalem as well as the missionary teachers and how the concept was re

Gestaltningar av offererfarenheter : Samtal med unga män som utsatts för brott

In this dissertation, young men's experiences of being victims of crime are analysed. Several kinds of material are considered in this study, but the primary data consist of informal, tape-recorded interviews with ten young men (17 to 21 year's old) who had been assaulted or mugged. Their accounts of their experiences are analysed using a number of constructionist, interactionist, and narrative pe

Quantum Chaos and Dissipation in Finite Fermi Systems

We address the problem of the dissipative character of collective motion in finite Fermi systems. We study this problem from the point of view of chaotic features of the fermionic degrees of freedom of the many-body Fermi systems. Our main aim is of two kinds: first, we investigate how quantum chaos sets in in many-body systems and then, we try to relate quantum many-body chaos of the intrinsic fe

Variationer av predikouppfattningar i Svenska kyrkan. En fenomenografisk undersökning om predikanter och åhörare.

This study describes, systematizes and analyses the variations of preachers' conceptions of their mission to preach and their listeners' conceptions of the sermon. It does so in a phenomenographic and theological perspective. The conceptions of preachers and their listeners of the mission to preach and the sermon respectively are investigated by way of interviews. The basic issues are what differe

Natriuretic Peptides and the Microcirkulation in Heart Failure Patients

The increased prevalence of chronic congestive heart failure (HF) is a tremendous challenge for society. In spite of effective medical treatment for acute HF, better pharmacological treatment for specific neurohormonal intervention and better diagnostic tools, e.g. biomarkers of natriuretic peptides, the morbidity and mortality due to this disease are still prominent. HF leads to vascular dysfunct

Robin Wood - brittisk filmkritiker

British film critic Robin Wood began to publish on film in 1960. Since then, he has written or co-written 13 books, and also published hundreds of essays and articles in books, in journals, and in different encyclopedias. At the same time, Wood has been a key figure in the development of what has become academic film studies. Wood was educated at Cambridge University, where he studied English lite

Vem ska bestämma? Dilemman kring effektivitetsrevisorns professionella utrymme - och riksrevisorns roll

Riksrevisionens första tio år har präglats av turbulens. En fråga som har vållat särskild debatt är inskränkningarna av effektivitetsrevisorns utrymme för självständigt utövande av det professionella omdömet. Detta kapitel ägnas åt den frågan. Det baseras på tio års nära forskning om Riksrevisionen. När myndigheten bildades valde riksrevisorerna att öka sitt eget inflytande över granskningarna, sa

Tarot : New age i bild och berättelse

In the course of my dissertation work, I have sought knowledge about what New Age is, contains, and conveys by looking at practice and rhetoric, how the participants act and reason regarding their commitment, as well as how the contents of the field is discussed. I have put an emphasis on the small details: the objects, the rituals, and the narrating. Using the tarot cards as a starting point, the

Kommunala huvudmannastrategier för kostnadspress och utveckling : en studie av kommunal teknik

The aim of the study is to improve the understanding of strategy in politically governed organisations. From the perspective of a specific responsible authority the main purpose of the study is to describe and analyse how strategies emerge and develop. Competitive tendering and inter-municipal co-operation, has been studied as a two principally different strategic approaches to reduce costs and st

Numerical Studies of Mixing in Pipes and Static Mixers

The objective of the present work was to investigate the mixing process in static mixers under laminar flow conditions, and in pipes during the displacement of dissimilar liquids. A numerical scheme and a method of characterizing static mixers were developed. The effects of changes in geometry, flow rate, viscosity ratio and volumetric flow rate ratio on the mixing process were investigated using