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Background: Women are less likely to receive oral anticoagulation or ablation for treatment of atrial fibrillation (AF). Identification of sex differences in arrhythmia characteristics and symptoms may lead to a better understanding of potential reasons for these differences. Objectives: To determine sex differences in AF with respect to heart rate, duration, burden, and symptoms in patients under
BACKGROUND: Retrospective studies have shown promising results using artificial intelligence (AI) to improve mammography screening accuracy and reduce screen-reading workload; however, to our knowledge, a randomised trial has not yet been conducted. We aimed to assess the clinical safety of an AI-supported screen-reading protocol compared with standard screen reading by radiologists following mamm
Phosphorus-driven eutrophication of surface waters persists across Europe and Water Framework Directive (WFD) implementation is slow. Calls for better management approaches advocate for involving multiple stakeholders, considering social, ecological and technological drivers, and applying ‘multi-level’ or ‘multi-scalar’ approaches. However, multi-level approaches rarely apply ‘scales’ and ‘levels’
PURPOSE: Groin hernia repair is a common procedure in general surgery, and is taught to and performed by surgeons early in their training. The aim of this observational study was to compare hernia repair performance and results of surgical trainees with those of a specialized surgeon, to identify what factors may influence short and long-term outcome, and areas for improvement in surgical training
Background: Because breast cancer (BC) is molecularly heterogeneous, diagnosis and treatment will likely benefit from comprehensive genetic profiling. However, routine, high-resolution sequencing is not feasible yet, due to implementation challenges associated with whole-genome sequencing of formalin-fixed paraffin embedded (FFPE) BC samples. Therefore, we explored the potential of an alternative
Responsible for roughly 40 % of global greenhouse gas emissions, energy usefor heating and cooling in the built environment constitutes a significant portionof annual total carbon emissions. The effort to decarbonise the heating andcooling sector necessitates efficient production, distribution and end use ofenergy. In this context, district heating and cooling is considered one of thecost-efficien
The book’s aim is to systematize normative assessments of the Court of Justice of the European Union’s decision-making process, defining ‘normative’ as an evaluation based on openly acknowledged, theoretically informed standards that take into account the institutional reality of the Court. This is important because the stakes are very high: the Court is a very influential institution, and the mot
Tuberculosis (TB) remains a major public health challenge, with financial and health impacts extending beyond treatment. Both the perspective adopted in cost-effectiveness analyses-which critically determines choices such as the inclusion of patient-incurred costs-and the extent to which long-term post-treatment considerations are incorporated have important policy implications. This study examine
Background: Skin pain is a common symptom in patients with chronic hand eczema (CHE); however, its association with increased analgesic use has not been thoroughly investigated. Objectives: To examine analgesic use (paracetamol, nonsteroidal anti-inflammatory drugs [NSAIDs], opioids and gabapentin/pregabalin) among patients with CHE compared to a control group. Methods: Data were obtained from the
Solid materials doped with rare-earth ions are considered an attractive platform for quantum information applications. One of the main reasons for this is the exceptionally long optical and hyperfine coherence times of the 4fn states, due to the shielding provided by the outer lying 5s and 5p electrons. This enables a large number of quantum operations before the system loses its coherence. Anothe
I denna avhandling utvecklar jag förståelsen kring avstigmatiseringsprocesser till att inkludera produkters avstigmatisering. Tidigare forskning kring avstigmatisering har främst fokuserat på individer, grupper, organisationer och industrier. Dock finns det en mängd empiriskt bevis som vittnar om att produktstigma har signifikanta effekter på marknadslogiker, inklusive enligt lag bestämda produktkIn this thesis, I develop our understanding of the destigmatization process to include product destigmatization. Previous research on destigmatization has primarily focused on that of individuals, groups, organizations, and industries. However, there is an abundance of empirical evidence showing that a product stigma has a significant bearing on market logics, including legal classification of pro
This study investigates how related variety in the regional employment mix affects the innovation output of a region. Departing from the idea of recombinant innovation, previous research has arguedthat related variety enhances regional innovation as inter-industry knowledge spillovers occur more easily between different but cognitively similar industries. This study combines a
This thesis investigates the role of artefacts in relation to human agency and design within a cognitive semiotics framework. It deals with questions such as What is agency? What are artefacts and how does agency relate to them? What kind of intentions are involved in the activity of designing? What is human-specific with respect to agency and design? How can the origins and evolution of design be
Purpose: To assess the association between cystatin C-derived estimates of kidney function and mortality and acute kidney injury (AKI) in sepsis. Materials and methods: Post-hoc analysis of sepsis patients in the FINNAKI-cohort (n = 802). Primary outcome was 90-day mortality. We measured plasma cystatin C and creatinine at intensive care unit (ICU) admission and estimated glomerular filtration rat
The number of people who live in bushfire-prone areas around the world is growing. In Australia, in the states of Victoria and New South Wales, over 1.5 million people live in areas rated as high to extreme bushfire risk in (SGS Economics and Planning 2019). As effects of climate change increase the size and severity of bushfires, and a greater number of people move into these at-risk areas, there
OBJECTIVE: This study explored the association of patients' demographics, health status, symptom severity, previous osteoarthritis (OA) care, and psychological status with the change in pain severity following a first-line intervention including education and exercise for OA provided nationwide in Swedish primary care. METHODS: This register-based cohort study included 23,309 people with knee or h
