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Context: Due to the complexity and challenging nature of radical prostatectomy (RP), it is likely that both short-and long-term outcomes strongly depend on the cumulative number of cases performed by the surgeon as well as by the hospital. Objective: To review systematically the association between hospital and surgeon volume and perioperative, oncologic, and functional outcomes after RP. Evidence
This article reports on the successful stabilization of the carrier-envelope phase of a 1-kHz laser system that includes a large grating stretcher, a regenerative amplifier, a multipass amplifier and a grating compressor. Phase stability for pulse energies up to 6 mJ is demonstrated using electronic feedback to the oscillator locking electronics as well as feedback via an acousto-optic programmabl
The opportunistic human pathogen Pseudomonas aeruginosa causes a wide range of diseases. To cross host innate immune barriers, P. aeruginosa has developed efficient strategies to escape host complement attack. In this study, we identify the 57-kDa dihydrolipoamide dehydrogenase (Lpd) as a surface-exposed protein of P. aeruginosa that binds the four human plasma proteins, Factor H, Factor H-like pr
In this article, I will apply parts of the method introduced by Linda Hutcheon in her recently reedited book A Theory of Adaptation (2010) and try to answer the question “why” an adaptation is made. I will particularly study three complex cases of adaptation, which might even put into question the definition of adaptation itself, but I will concentrate on aspects related to immersion and self-refe
The cysteine proteases are enzymes found in every kingdom of life. Clan CA is the largest of the cysteine protease clans, with members all displaying a Cys/His/Asn(Asp) catalytic triad responsible for hydrolysing the peptide bond within the substrate. To regulate the activity of the proteases, another group of proteins act as natural inhibitors (cysteine protease inhibitors) and bind to the protea
Erysipelas is a common and severe infection where the aetiology and optimal management is not well-studied. Here, we investigate the clinical features, bacteriological aetiology, and treatment of erysipelas.
Invasive infections remains one of the leading causes of death due to infections over the world, and efficient treatment remains elusive. One of the major causes of sepsis and other invasive infections is pathogenic streptococci that cause a wide range of clinical manifestations in humans. Group A and group G streptococci have both been shown to cause both infections of milder ranges as well as se
Background: Randomized placebo-controlled trials represent the gold standard in evaluating healthcare interventions but are rarely performed within orthopedics. Ethical concerns or well-known challenges in recruiting patients for surgical trials in general have been expressed and adding a placebo component only adds to this complexity. The purpose of this study was to report the challenges of recr
Abstract is not available
We extend the recursion formula for matrix Bessel functions, which we obtained previously, to superspace. It is sufficient to do this for the unitary orthosymplectic supergroup. By direct computations, we show that fairly explicit results can be obtained, at least up to dimension 8x8 for the supermatrices. Since we introduce a new technique, we discuss various of its aspects in some detail. (C) 20
The influence of a small hydrophobic solute (octanoic acid) on the flux reduction and the flux recovery of two ultrafiltration membranes was studied in this investigation. The two membranes were made of polyether sulfone and regenerated cellulose, both with a nominal molecular weight cutoff of 20,000 Da. The concentration of the octanoic acid solution was found to have a significant influence on n
According to the so-called Substituted Judgment Standard, a surrogate decision maker, acting on behalf of an incompetent patient, ought to make that health care decision which the patient would have made, had the latter been competent. The most common way of justifying the Substituted Judgment Standard is to maintain that this standard extends patients’ opportunities for self-determination to situ
We have demonstrated in sensitized rats that the immediate response to endointestinal challenge with allergen (10(-6) M ovalbumin) is characterized by mucosal exudation of plasma with little or no concomitant change in the mucosal absorption capacity. The luminal entry of plasma macromolecules also leaves the light microscopic structure and the ultrastructure of the mucosa unaffected. It is possib
Researchers from various disciplines have been pursuing better understanding of learning and forgetting processes. A range of mathematical models, sometimes based on empirical data, has been developed to measure the effect of production breaks on the learning process. Thus far, researchers and practitioners have not resolved the issue of how learning and forgetting interacts. However, some of the
The process of steam drying a bed of porous spheres is analysed in terms of a hybrid model that makes use of volume averaged transport equations for the fluid flowing in the bed and point equations for the heat and mass transport taking place in the spheres. To verify the model, a series of experiments with varying mass flux and steam temperature were carried out at atmospheric pressure using cera
The focus of this thesis is on the use of wave splitting in electromagnetic direct and inverse scattering problems. Wave splitting offers a decomposition of wave fields into appropriate input and output wave constituents. Several different wave splittings are studied including one-dimensional, multi-dimensional energy-flux, and multi-dimensional locally exact wave splittings. The Bremmer series is
Osmoderma eremita (Scopoli) is an endangered scarab beetle living in hollow trees. It has mainly been known for its characteristic odor, typically described as a fruity, peachlike or plumlike aroma. The odor emanating from a single beetle can sometimes be perceived from a distance of several meters. In this paper, we show that the characteristic odor from O. eremita is caused by the compound (R)-(
Twenty-five patients with isolated unilateral cleft lip took part in a follow-up study at a mean age of 28.6 years. All had had a primary, Millard lip repair, at a mean age of 4.6 months. In 20 patients, at least one secondary correction had been undertaken during adolescence. The overall long-term outcome was thought to be good, leaving a fairly inconspicuous fine lip scar and acceptable nose con
