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Wild-type (F/B), constitutively active (F/B*), and three kinase-inactive (F/Ba-, F/Bb-, F/Bc-) forms of Akt/protein kinase B (PKB) were permanently overexpressed in FDCP2 cells. In the absence of insulin-like growth factor-1 (IGF-1), activities of PKB, cyclic nucleotide phosphodiesterase 3B (PDE3B), and PDE4 were similar in nontransfected FDCP2 cells, mock-transfected (F/V) cells, and F/B and F/B-
We have investigated the formation of vesicles in the binary system of a triblock copolymer of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO) with the average composition EO5PO68EO5 in water. Vesicles are formed when a solution of unimers is heated into a two-phase region where, at equilibrium, a concentrated lamellar phase coexists with a dilute solution of unimers. The vesicles were
In 91 patients (36 men, 55 women) who were hospitalized with symptoms of acute cholecystitis, cholescintigraphy was performed with 99m-Tc-ethyl-IDA, in order to evaluate the method in the diagnosis of acute inflammatory disease of the gallbladder. Five groups of patients were recognized: (A) abnormal scintigraphy and verified gallbladder disease, (B) abnormal scintigraphy without verified gallblad
Abstract is not available
Directed and elliptic flow of pi(0) - decay photons in 158 A GeV Pb+Pb collisions has been studied near midrapidity in an analysis of data obtained with the photon spectrometer LEDA of the WA98 experiment at the CERN SPS. Preliminary results on the rapidity and transverse momentum dependence of the flow have been obtained for various centrality classes for p(T) > 0.2 GeV/c and 2.3 < y < 2.9. The r
Antimony trisulfide (Sb2S3) is used as a lubricant in friction material. X-ray diffraction analysis revealed Sb in 3/3 disc brake pads (range 41,000-46,000 mg/kg) and in 2/2 disc brake dust samples (21,000 and 17,000 mg/kg) from trucks. Considerably lower concentrations were found in drum brake pads (3/5, 59-6400 mg/kg) and in drum brake dust (4/18, 78-2800 mg/kg). Other toxic metals were also det
BACKGROUND: Suffering a myocardial infarction (MI) is a life-threatening event that impacts not only on the individual concerned but also on the next of kin. However, there seems to be a paucity of naturalistic inquiries that focus specifically on midlife next of kin and their experience of being close to a relative who has suffered an MI. This study aims to elucidate the experience of being a mid
English ergative verbs in one-participant constructions such as ‘The door opens’ often correspond to reflexive verbs or -S forms in Norwegian and Swedish. Following Kemmer (1993) such constructions profile spontaneous event meaning and belong to the middle domain. This study uses corpus methodology to explore spontaneous-event marking in Norwegian and Swedish from the point of view of Kemmer’s sug
Photoreceptor adaptation ensures appropriate visual responses during changing light conditions and contributes to colour constancy. We used behavioural tests to compare UV-sensitivity of budgerigars after adaptation to UV-rich and UV-poor backgrounds. In the latter case, we found lower UV-sensitivity than expected, which could be the result of photon-shot noise corrupting cone signal robustness or
The polyamines are important for a variety of cellular functions, including cell growth. Their intracellular concentrations are controlled by a complex network of regulatory mechanisms, in which antizyme (Az) has a key role. Az reduces the cellular polyamine content by down-regulating both the enzyme catalysing polyamine biosynthesis, ornithine decarboxylase (ODC), and the uptake of polyamines. Th
A detailed investigation of the decomposition reactions and decay in the hydrogen storage capacity during repeated hydrogen release and uptake cycles for the reactive composite LiBH4-Al (2:3) is presented. Furthermore, the influence of a titanium boride, TiB2, additive is investigated. The study combines information from multiple techniques: in situ synchrotron radiation powder X-ray diffraction,
Priority effects occur when a species or genotype with earlier arrival has an advantage such that its relative abundance in the community or population is increased compared with later-arriving species. Few studies have dealt with this concept in the context of within-species competition. Skeletonema marinoi is a marine diatom that shows a high degree of genetic differentiation between populations
Iodine added to iodide-based ionic liquids leads to extraordinarily efficient charge transport, vastly exceeding that expected for such viscous systems. Using terahertz time-domain spectroscopy, in conjunction with dc conductivity, diffusivity and viscosity measurements we unravel the conductivity pathways in 1-methyl-3-propylimidazolium iodide melts. This study presents evidence of the Grotthuss
Intrusive recollections are one of the core symptoms of Post-Traumatic Stress Disorder (PTSD). Flashbacks, a subcategory of intrusive memory phenomena, are considered exclusive to the disorder, indicating a direct correlation between the traumatic event, the memory encoding and the subsequently intruding flashback. The experience of a flashback is defined as the highest degree of reliving, and the
The use of the past tense form (or ta-form) as an imperative in modern Japanese has been touched upon by various scholars. However, a descriptive analysis of the phenomenon has not yet been performed. In this thesis, the characteristics of this type of ta-form usage and the rules governing it are described through a contrastive analysis of the way in which the usage of imperative -ta differs from
Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventricular ejection fraction, are well recognized, their genetic determinants remain inadequately understood. In this study, we report a genome-wide association study of HF and its subtypes in a sample of 1.9 million individuals. A total of 153,174 individual
