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Mouse mammary tumor virus (MMTV) has a proven role in breast carcinogenesis in wild mice and genetically susceptible laboratory inbred mice. The carcinogenic characteristics of this virus are enhanced by estrogen and other steroid hormones. MMTV-like envelope gene sequences, with 95% homology to MMTV have been identified in approximately 40% of breast cancers in US, Australian and Argentinian wome

We describe a fast and accurate collision-detection algorithm specialised for models deformed by morphing. The models considered are meshes where the vertex positions are convex combinations of sets of reference meshes. This new method is based on bounding-volume trees that are extended to support efficient tree-node updates by blending associated sets of reference bounding volumes. With our appro

In 1998, I estimated the number of birds killed on Swedish roads at about ten million. This estimate was ten times higher than a previous estimate from 1978. 1 suspected that the difference depended on different methods, and that my estimate was the most correct one. At that time I was not aware of a careful Danish study, which estimated the total road kill of birds at 3.3-3.5 million in that coun

Background. It has been previously demonstrated that addition of anti-LFA-1 to a combination of CTLA4Ig and anti-CD40L induces the permanent acceptance of dopaminergic fetal pig xenografts when transplanted into the brain of wild-type mice. The purpose of this study was to test whether this costimulation blockade also can induce acceptance of adult pig islets transplanted to C5713L/6 mice with str

Electronic and structural properties of GaAs(100)(2x4), InAs(100)(2x4), and Sb/InAs(100)(2x4) reconstructed surfaces have been studied by synchrotron-radiation photoelectron spectroscopy and scanning tunneling microscopy (STM). Based on the difference spectrum of As 3d core-level spectra of III-As(100)(2x4), measured in different surface-sensitivity conditions, as well as the line shape of the As

This report presents the derivation of a nonlinear model for the ETH helicopter laboratory process. The model is derived using Euler-Lagrange equations together with relations from propeller theory. The model is formulated as a state-space model, which enables straightforward implementation in standard simulation tools such as Simulink (TM). A set of model parameters computed from the ETH process

Adrenocorticotrophic hormone (ACTH) facilitates the synthesis of adrenal glucocorticoids by maintaining the enzymes that control the side-chain cleavage of cholesterol, the rate-limiting step in the biosynthesis of steroids 1]. Thus, ACTH is involved in the control of adrenal lipid metabolism. Recent studies have revealed that treatment with ACTH in pharmacological dosage also influences plasma li

An experimental model is presented that allows qualitative as well as quantitative studies of the soft tissue response to implant materials used in reconstructive surgery. Plugs of non-alloyed titanium and polymers (Teflon, Delrin) were inserted into the abdominal wall of rats, with a portion of the plug penetrating through the peritoneum into the abdominal cavity. The tissue reaction was evaluate

In a prospective study on 516 breast cancer patients flow cytometry DNA ploidy and number of cell populations (defined as number of DNA stem lines) detected in the primary tumor were evaluated for prognostic purposes. the median follow-up time was about 5 years. in the 241 node negative cases, those patients with three or more cell populations had the worst prognosis, with a distant recurrence-fre

The role of fluid-phase regulators of complement is to inhibit excessive complement activation and maintain homeostasis in blood. By binding to and inactivating complement components on cell surfaces, they can also protect autologous cells from complement-mediated cytotoxicity and phagocytosis. In this study, we wanted to find out whether C4b-binding protein (C4bp), a fluid-phase regulator of the

Studies focusing on genetic and social influences on maternal adjustment will illumine mother's marriage, parenting, and the development of psychopathology in her children. Recent behavioral genetic research suggests mechanisms by which genetic and social influences determine psychological development and adjustment. First, heritable, personal attributes may influence individuals' relationships wi

In animal ethics animal capacity to suffer and experience is a selfevident point of departure when elaborating theories for respecting animals. Less often the practical consequences of "respecting an animal" is discussed in these theories, still they want to influence our behavior towards the animals. So, in order to know what is respectful, we need to connect scientific knowledge about an animal

The aqueous self-assembly of a novel lysine-derived surfactant with a gemini-like architecture, designated here as 12-Lys-12, has been experimentally investigated for the amphiphile alone in water and in a mixture with dodecyltrimethylammonium bromide (DTAB). The neat surfactant forms interesting micrometer-sized rigid tubules in the dilute region, resulting in very viscous solutions. For the cata

Sprickbildning i puts på isolering har inträffat i ökande omfattning på senare tid. I denna rapport redovisas resultaten från inledande studier på provväggar i laboratorium. Två provväggar, med respektive utan fönster samt med olika fasthållning, har studerats.

Time relations among trauma, pulmonary and systemic circulation, and lung function were studied in pigs. Eleven animals (b.w. 25-30 kg) were investigated under balanced anesthesia. Ventilation was mechanically controlled. Hemodynamics, pulmonary ventilation, and gas exchange were serially recorded. Seven animals were pretreated with 40% ethanol in saline and four with saline only. Ninety minutes a