Relapsing polychondritis is an autoimmune disease in which an inappropriate immune response destroys cartilage. Cartilage of the ears, larynx and nose rather than spine and joint cartilage is affected by a chronic relapsing and erosive inflammation. Several animal models for relapsing polychondritis have been published in which immunization with various cartilage proteins induces a variety of chon

Chronic treatment with epidermal growth factor (EGF) stimulates growth of all wall layers of the urinary tract in pigs and rats. Herein, we investigated the acute effects of EGF on detrusor smooth muscle activity. For in vivo examination, awake rats received EGF (75 micrograms/kg) intravenously and detrusor smooth muscle activity was monitored cystometrically. The EGF bolus caused no alteration in

Popular Abstract in Swedish Skeletthälsa och livsstilsbeteenden hos unga kvinnor I Sverige kommer ungefär 50 % av alla kvinnor att drabbas av en fraktur någon gång under sitt liv. Ett starkt skelett med hög mängd benmassa är det som främst bidrar till att förebygga benskörhetsfrakturer. Kvinnor har efter ungdomsåren mindre mängd benmassa än män och mängden benmassa minskar hos kvinnor snabbare i The overall aim of this prospective observational study with a salutogenic approach was to investigate bone mineral density (BMD) and BMD changes in the heel bone, in a group of healthy women, in relation to physiological factors and lifestyle behaviours over a two-year period as well as investigating the women’s view of their lifestyle behaviours. Data were collected in 1999 (T1) and 2001 (T2). H

A 3D finite element (FE) model of an implanted pelvis was developed as part of a project investigating an all-polymer hip resurfacing design. The model was used to compare this novel design with a metal-on-metal design in current use and a metal-on-polymer design typical of early resurfacing implants. The model included forces representing the actions of 22 muscles as well as variable cancellous b

A general question for linkage disequilibrium-based association studies is how power to detect an association is compromised when tag SNPs are chosen from data in one population sample and then deployed in another sample. Specifically, it is important to know how well tags picked from the HapMap DNA samples capture the variation in other samples. To address this, we collected dense data uniformly

Fiberoptic bronchoscopy with bronchoalveolar lavage and protected specimen brush technique has become an established method for etiologic diagnosis in severe forms of pulmonary infections during recent years. In this study, including 62 bronchoscopies in 53 patients, a standardized program, covering all important pulmonary pathogens, has been evaluated in a heterogeneous group of patients. Results

We have found necessary and sufficient conditions for the n-particle density to be N-representable for infinite A, if n is even. There are some mild restrictions on the one-density for these conditions to apply. The method is based on the Mercer expansion theorem. We suggest a simple method for total energy calculations based on this characterization also if the number of particles is finite. (c)

We demonstrate high contrast quantum interference between one-photon and three-photon absorption pathways in an organic solid at room temperature. Illumination of a thin polymer film activated with fluorescing dendrimer chromophores of large three photon absorption cross section with two simultaneous femtosecond pulses at near-IR frequency. and its third harmonic UV frequency 3. results in a spati

A peripheral nerve injury has a profound impact on the patient’s life and such an injury causes high costs for society. A peripheral nerve injury is a very complex injury because it involves both peripheral and central components of the nervous system all the way from targets at muscle and skin receptors up to the brain. In the neuron and its supporting cells—mainly Schwann cells—there are numerou