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A combined extended triple collocation and cumulative distribution function merging framework for improved daily precipitation estimates over mainland China

Accurate monitoring of daily precipitation is essential for many applications, such as simulation and prediction of watershed water-related disasters. However, precipitation data from satellite and gauge-based precipitation products face challenges in capturing true observations because of their large uncertainties. To improve daily precipitation estimates, this study proposed a new merging framew

Navigating sustainable futures : The role of terminal and instrumental values

Values have been discussed both in relation to the normative character of Ecological Economics and, albeit implicitly, in conceptions of human beings. Nevertheless, a conceptualisation of individually-held values remains underdeveloped. Scholars who do engage on a conceptual level tend to focus on the values of nature in the context of ecosystem services, with less emphasis on: (a) more generally-

Mediators, Metabolites and Atypical Immune Cells in Cardiovascular Disease

Cardiovascular disease (CVD) remains, despite intense research, the most common cause of death world-wide. The main underlying cause of CVD is atherosclerosis, which is characterised by chronic inflammation. CVD and atherosclerosis have a complex aetiology, which necessitates research into multiple areas in order to gain insight into the pathogenesis and find novel markers that could aid in identi

Vulvovaginal candidiasis and type 2 diabetes : A nationwide retrospective cohort study

Aims: To examine whether vulvovaginal candidiasis (VVC) precedes type 2 diabetes and to quantify the possible time period between VVC and subsequent diabetes. Material and Methods: We conducted a nationwide retrospective primary healthcare study including 1 838 929 women aged 35–65 years in Sweden (2007–2018). Cox regression models were used to examine associations between VVC and type 2 diabetes,

The association between height and risk of lung cancer subtypes in men and women in the Netherlands Cohort Study

Objectives: Previous studies found no or weak positive associations between height and lung cancer (LC) risk, with differences between sexes. Few studies stratified the association by smoking status and LC subtype. This prospective study investigated the association between height and risks of overall LC and LC subtypes (i.e., adenocarcinoma, squamous cell carcinoma, small cell carcinoma, large ce

Measurements of laminar burning velocities and kinetic modelling of two symmetrical ketones : di-ethyl ketone and di-isopropyl ketone

Laminar burning velocities (SL) of di-ethyl ketone (DEK) + air and di-isopropyl ketone (DIPK) + air mixtures were measured using the heat flux method at 305-358 K and equivalence ratios of 0.7–1.4 under atmospheric pressure. Data inconsistency was found between the present SL of di-ethyl ketone + air mixtures and those reported in the literature. Moreover, existing DEK and DIPK combustion kinetic

The oxidation of carbon nanostructures imaged by electron microscopy : Comparison between in-situ TEM and TGA experiments

The development of a model of carbon oxidation has engaged researchers for decades. Yet many outstanding questions remain due to the inability to experimentally study the details of the oxidation. Today, novel techniques such as environmental transmission electron microscopy (ETEM), allowing for in-situ nanoscale observations of the oxidation process, can help illuminate some of these questions. I

Dispositional and state sadness, interpersonal features, and internalizing/externalizing symptoms : A network analysis

Sadness serves adaptive functions in restructuring one's objectives and strategies in loss situations. This study examined the relationship between the effects of sadness, social components, and psychopathological issues in children, distinguishing between state and dispositional sadness. A semi-structured written interview about a specific moment of sadness and questionnaires to measure interpers

No mess with mesh; vaginal natural orifice transluminal endoscopic surgery (vNOTES) autologous posterior rectus fascia mesh for vaginal urinary incontinence procedures

Urinary incontinence affects 25–45 % of women with the gold standard surgical approach being placement of mid-urethral synthetic slings; tension-free vaginal tape (TVT) and trans-obturator tape (TOT). Due to the controversies regarding vaginal mesh the last decade, an increasing demand has evolved for incontinence treatment without vaginal synthetic mesh. The short term results of autologous rectu

LSPR anisotropy minimization by sequential growth of Ag nanoparticles on nanoripple patterned Si surface for SERS Application

The present work describes the formation of low-aspect-ratio Ag nanoparticles (NPs) arrays by sequential deposition of Ag from different growth directions on a nanoripple-patterned Si substrate, produced by low-energy ion beam irradiation. It is observed that the growth of Ag-NPs on ripple surfaces is direction-dependent due to the asymmetric ridge of the ripple pattern. This asymmetric ridge can

Association of Body Mass Index and Parkinson Disease A Bidirectional Mendelian Randomization Study

Background and Objectives: The role of body mass index (BMI) in Parkinson disease (PD) is unclear. Based on the Comprehensive Unbiased Risk Factor Assessment for Genetics and Environment in PD (Courage-PD) consortium, we used 2-sample Mendelian randomization (MR) to replicate a previously reported inverse association of genetically predicted BMI with PD and investigated whether findings were robus

Investigating Ras homolog gene family member C (RhoC) and Ki67 expression following external beam radiation therapy show increased RhoC expression in relapsing prostate cancer xenografts

Ras homolog gene family member C (RhoC) is a GTPase involved in cell migration, implicated in epithelial-mesenchymal transition and treatment resistance and metastasis of cancer. For example, RhoC has been shown to be involved in resistance to radiation in cervical carcinoma. Here, the effect of X-ray irradiation on RhoC expression in prostate cancer (PCa) xenografts was investigated in both xenog

TOI−757 b: an eccentric transiting mini−Neptune on a 17.5−d orbit

We report the spectroscopic confirmation and fundamental properties of TOI−757 b, a mini−Neptune on a 17.5−d orbit transiting a bright star (V = 9.7 mag) discovered by the TESS mission. We acquired high−precision radial velocity measurements with the HARPS, ESPRESSO, and PFS spectrographs to confirm the planet detection and determine its mass. We also acquired space−borne transit photometry with t

The Expansion of Colonial State Healthcare in Twentieth Century British Africa

We chart and assess the scope and utilisation of government-provided hospital infrastructure in British Africa, c. 1900-1960. Using various archival sources, we examine the heterogeneity in colonial administrations’ investment into curative healthcare provision across various regions of British Africa. Our research highlights significant disparities in healthcare provision during the colonial peri