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Background One potential cause of comorbidity is the direct causal effect of one disorder - A - on risk for subsequent onset of disorder B. Could genetic risk scores be utilized to test for such an effect? If disorder A causally impacts on risk for disorder B, then genetic risk for disorder A should be lower in cases of disorder A with v. without a prior onset of B. Methods In all individuals (n =

This study explores how Swedish women narrate experiences of hormonal contraceptives through utilizing the frameworks of biomedicalization and reproductive justice, adding a social justice perspective previously lacking. Ten in-depth interviews were conducted with women who had experience of using hormonal contraception. Political narrative analysis illuminated how these women moved narratively bo

Vasopressin is a pleiotropic hormone that controls body fluid homeostasis. Vasopressin has also been proposed to be involved in erythropoiesis, thrombocyte activity and inflammation. However, whether increasing vasopressin is associated with changes in hematopoietic markers is not known. To evaluate this gap of knowledge we measured the vasopressin marker copeptin and markers of erythropoiesis (er

The medial temporal lobe (MTL) cortex, located adjacent to the hippocampus, is crucial for memory and prone to the accumulation of certain neuropathologies such as Alzheimer's disease neurofibrillary tau tangles. The MTL cortex is composed of several subregions which differ in their functional and cytoarchitectonic features. As neuroanatomical schools rely on different cytoarchitectonic definition

Objective Immunoglobulin A vasculitis (IgAV) is the most prevalent primary childhood vasculitis in Sweden, but is considerably rarer in adults. This study aims to describe the epidemiology, clinical characteristics and renal outcome of adult-onset IgAV in Skåne, Sweden. Methods The study area consisted of Skåne, the southernmost region of Sweden, with a population ≥18 years of 990 464 on 31 Decemb

Background: Home oxygen therapy (HOT) improves survival in patients with hypoxaemic chronic respiratory disease. Most patients evaluated for HOT are former or active smokers. Oxygen accelerates combustion and smoking may increase the risk of burn injuries and fire hazards; therefore, it is considered a contraindication for HOT in many countries. However, there is variability in the practices and p

This systematic review captures research on doctoral students’ perspectives of supervision. The aim was to capture research on aspects of importance to enhance professional development for supervisors in a global perspective, as well as describe the characteristics of the body of research. Five aspects of supervisors’ competences, which have previously been found to be important for successful sup

Exclusion zones in the cross-correlations between critical points (peak-void, peak-wall, filament-wall, and filament-void) of the density field define quasi-standard rulers that can be used to constrain dark matter and dark energy cosmological parameters. The average size of the exclusion zone is found to scale linearly with the typical distance between extrema. The latter changes as a function of

Middle managers often find themselves in a challenging position: They have to impress different audiences in somewhat incompatible ways and represent and enact managerial ideals and expectations that may be detrimental to their work identities. This study explores role distancing as an alluring coping strategy. Role distancing – acts that express separateness between the individual and the enacted

Aim: To increase survival in out-of-hospital cardiac arrests (OHCA), great efforts are made to improve the number of voluntary first responders (VFR). However, evidence of the potential utility of such efforts is sparse, especially in rural areas. Therefore, the aim was to describe and compare response times for emergency medical services (EMS), fire and rescue services (FRS), and VFR during OHCA

Natural selection is notoriously dynamic in nature, and so, too, is sexual selection. The interactions between phytophagous insects and their host plants have provided valuable insights into the many ways in which ecological factors can influence sexual selection. In this review, we highlight recent discoveries and provide guidance for future work in this area. Importantly, host plants can affect

Syftet med denna artikel är att undersöka föreställningar om nedväxtsamhället som ett alternativ till grön tillväxt för att förstå och hantera klimatkrisen. Med utgångspunkt i aktuell tillväxtkritisk forskningslitteratur undersöks hur författare har föreställt sig ett framtida samhälle präglat av nedväxt. Artikelns analytiska ansats är att söka urskilja mönster och tendenser genom en systematisk gThe purpose of this article is to investigate how sociological imagination can be put to work for creating notions of the radically different as an alternative to the contemporary strategy of green growth for understanding and managing the climate crisis. Based on current growth-critical research literature, it examines how a number of authors have envisioned a future society characterized by degr

Arctic clouds are sensitive to atmospheric particles since these are sometimes in such low concentrations that clouds cannot always form under supersaturated water vapor conditions. This is especially true in the late summer, when aerosol concentrations are generally very low in the high Arctic. The environment changes rapidly around freeze-up as the open waters close and snow starts accumulating

Increasing nutrient concentrations (eutrophication) and water color due to dissolved organic matter (brownification) pose continuous threats to freshwater ecosystems worldwide, threatening ecosystem services like drinking water supply. Changing the increasing trends of eutrophication and brownification on our aquatic ecosystems is challenging. However, constructed wetlands could be a potential loc

Non-aqueous precipitating amine systems for carbon capture allows for CO2 desorption at lower temperatures than conventional aqueous amine systems and can potentially reduce the energy requirement for regeneration. In this work, the influence of water accumulation that may arise from humid gases entering the absorption column was investigated for absorption systems containing 2-amino-2-methyl-1-pr

Autophagy is an essential quality control mechanism for maintaining organellar functions in eukaryotic cells. Defective autophagy in pancreatic beta cells has been shown to be involved in the progression of diabetes through impaired insulin secretion under glucolipotoxic stress. The underlying mechanism reveals the pathologic role of the hyperactivation of mechanistic target of rapamycin (mTOR), w

BACKGROUND: To clarify, in a national sample, associations between risk for seven psychiatric and substance use disorders and five key transitions in Sweden's public educational system. METHODS: Swedish-born individuals (1972-1995, N = 1 997 910) were followed through 12-31-2018, at mean age 34.9. We predicted, from these educational transitions, risk for major depression (MD), obsessive-compulsiv

IntroductionSpeech in children with cleft palate can be affected by velopharyngeal dysfunction, which persists after primary palate repair. The incidence of surgery to correct velopharyngeal dysfunction in this patient group has previously been reported as 2.6–37%. We aimed to investigate the incidence of velopharyngeal dysfunction surgery in Swedish children with cleft palate and to examine poten