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The ESS Neutrino Super-Beam (ESSnuSB) is a proposed long-baseline neutrino oscillation experiment, performed with a high-intensity neutrino beam, to be developed as an extension to the European Spallation Source proton linac currently under construction in Lund, Sweden. The neutrinos would be detected with the near and far detectors of the experiment, the former within several hundred meters of th
Aims: Ventricular longitudinal function measured as basal-apical atrioventricular plane displacement (AVPD) or global longitudinal strain (GLS) is a potent predictor of mortality and could potentially be a predictor of heart failure-associated morbidity. We hypothesized that low AVPD and GLS are associated with the combined endpoint of cardiovascular mortality and heart failure-associated morbidit
Introduction: Optimal antithrombotic treatment after an acute coronary syndrome (ACS) in patients with atrial fibrillation is unclear. Data on outcomes in patients on concomitant ticagrelor and the novel oral anticoagulants (NOAC) is scarce. This study therefore sought to describe patient characteristics and treatment outcomes in patients with atrial fibrillation and ACS treated with concomitant t
The thesis elaborates on four different projects focusing on synthesizing symmetry-related molecules and investigating their performance as catalysts for asymmetric catalysis or as monomers for hydrogen bond-based self-assembly.Chapter 2 describes a new method to desymmetrize a meso-ligand. Two pseudo-Cs-symmetric bissalen complexes from a meso bissalen ligand and two different pairs of metal ions
In-situ remediation of contaminated groundwater often relies on the installation of a treatment zone degrading the pollution plume. In such projects, adequate delivery of remediation agents in the whole target volume is not trivial. Monitoring the spatial distribution of injected reagents is important for engineers and decision-makers, in order to determine the need of more careful injection in so
Quantum dots embedded in an electronic circuit allow precise control over the charge transport behaviour of the system: Charge carriers can be individually trapped or precisely shuffled between a series of quantum dots in a strictly sequential manner. This introduces ideal conditions to study fundamental quantum physics and such devices are in the focus of extensive efforts to develop quantum info
Background: While HPV vaccination uptake in Sweden is quite high, at around 80%, vaccine hesitancy remains an issue in countries throughout Europe. The latter can be related to a contemporary context of increased contestation of expert knowledge and of a large share of information on health-related issues including vaccination today being sought via the internet. Still, there is a paucity of recen
Renal cell carcinoma (RCC) is a tumour type with an indolent growth pattern and rather vague symptoms. The present study developed a platform for liquid biopsy of RCC based upon the isolation of circulating tumour cells (CTCs). Founded on the observation that RCC tumour cells are considerably larger than leucocytes, the present study employed a microfluidics-based system for isolation of RCC CTCs
The formulation of semolina pasta with reduced starch digestibility is of prime importance to deal with the adverse effects of the intake of rapidly digested carbohydrates on human health. This work focused on the effects of the production method (extrusion and lamination) and the addition of commercial Type 2 resistant starch (RS) on the molecular organization and in vitro starch digestibility of
In the challenge to reduce CO2, NOx and PM emissions, the application of natural gas or biogas in engines is a viable approach. In heavy duty and marine, either a conventional dual fuel (CDF), or a reactivity-controlled compression ignition (RCCI) approach is feasible on existing diesel engines. In both technologies a pilot diesel injection is used to ignite the premixed natural gas. However, the
Recycling is an important area to improve to reduce negative impact on the environment. With increased material recovery, less virgin materials are needed to provide the same benefits for the society. Aluminium is an important metal in the efforts to reduce negative climate impact. Demand for wrought aluminium will heavily increase with electrification of vehicles. However, with today’s recycling,
Driven by the Paris agreement and tightening IMO regulations, the marine sector is focusing on lowering engine emissions and moving to low-carbon fossil or renewable fuel such as methane. The dual-fuel concept allows the usage of methane as main energy-source in diesel engines. A small pilot diesel injection acts as an ignition source for the premixed methane. It was investigated how NOx formation
En fråga som tidigare inte fått mycket uppmärksamhet, men som på senare tid hamnat i fokus, är utrymningsmöjligheterna vid brand i byggnader där vertikal förflyttning är en förutsättning. Sedan terroristattacken mot World Trade Center 2001 har flertalet studier belyst att användandet av hissar för utrymning skulle kunna vara en möjlig lösning för att effektivisera utrymningen av höga byggnader. TrAs tall buildings and deep underground structures around the world increase in both numbers and complexity, the issues with evacuation of such structures, e.g., fatigue during evacuation or difficulties for people with functional limitations to evacuate, become more prominent. Elevator evacuation could be a possible solution to these matters but in order for such elevators to be an effective solut
Purpose: To develop self-navigated motion correction for 3D silent zero echo time (ZTE) based neuroimaging and characterize its performance for different types of head motion. Methods: The proposed method termed MERLIN (Motion Estimation & Retrospective correction Leveraging Interleaved Navigators) achieves self-navigation by using interleaved 3D phyllotaxis k-space sampling. Low resolution na
This paper explores the idea of the entrepreneurial university and how it differs in diverse regional and institutional settings. From the analysis of university engagement in a regional economic development programme in fifteen city-regions in England (UK), this study identifies three roles that entrepreneurial universities play in regional economic development as growth supporter, steerer, and d
BackgroundAdrenomedullin is a vasoactive hormone with potentially prognostic and therapeutic value, which mainly has been investigated in intensive care unit (ICU) settings. The triaging in the emergency department (ED) of patients to the right level of care is crucial for patient outcome.ObjectivesThe primary aim of this study was to investigate the association of bioactive adrenomedullin (bio-AD
