Filetype
Størling and colleagues hypothesise in this issue (Diabetologia DOI: 10.1007/s00125-013-3045-3 ) that post-translational modification (PTM) of autoantigens might create tissue-specific neo-epitopes that could trigger type 1 diabetes. Data on PTM of islet autoantigens are scarce and readers should not believe that the PTM hypothesis is supported by strong experimental evidence. The proposed genetic
Bone marrow-derived natural killer (NK) cells constitute the major subset of cytotoxic lymphocytes in peripheral blood. They provide innate defense against intracellular infection or malignancy and contribute to immune homeostasis. Large numbers of NK cells are also present in tissues, including the liver and uterus, where they can mediate immunosurveillance but also play important roles in tissue
Postanoxic electrographic status epilepticus (ESE) is considered a predictor of poor outcome in resuscitated patients after cardiac arrest (CA). Observational data suggest that a subgroup of patients may have a good outcome. This study aimed to describe the prevalence of ESE and potential clinical and electrographic prognostic markers.
In this prospective study, 11 consecutive patients with neoplastic colorectal lesions (median size 20 mm, range 15 - 25 mm) underwent endoscopic polyp removal by underwater endoscopic mucosal resection (EMR). Six lesions were removed en bloc and five lesions were removed by piecemeal resection. Pathological examination revealed seven R0 resections, and in four cases the pathology could not be dete
Species diversity in sandy grasslands is threatened by decalcification and eutrophication. To determine the most appropriate conditions for red-listed gasteromycete fungi in such grasslands, we investigated their pH preferences in this habitat in southern Sweden. During two winters soil samples were collected from the vicinity of mycelia of these species. Chemical analysis revealed that none of th
There is increasing awareness that the medications used to treat the motor symptoms of Parkinson's disease (PD) contribute to the development of behavioral addictions, which have been clinically defined as impulsive compulsive behaviors (ICBs). These features include pathological gambling, compulsive sexual behavior, binge eating, compulsive shopping, excessive hobbyism or punding, and the excessi
In this paper, we study whether pronouns in news media are used in evaluative contexts reflecting psychological biases. The evaluative contexts of pronouns are measured by computerized sentiment analysis, enabling analyses of large text corpora and subtle evaluative differences in how words are used in contexts. The results show that self-inclusive personal pronouns (We, I) occur in more positive
All patients with palliative and end of life care needs should be guaranteed equal and safe treatment and care, regardless of their disease or site of care. The inclusion of quality indicators in national guidelines and other guiding documents supports quality assurance and improvement in provision of care. The aim of this paper was to review existing quality indicators in national Swedish policy
A plant bioreactor has enormous capability as a system that supports many biological activities, that is, production of plant bodies, virus-like particles (VLPs), and vaccines. Foreign gene expression is an efficient mechanism for getting protein vaccines against different human viral and nonviral diseases. Plants make it easy to deal with safe, inexpensive, and provide trouble-free storage. The b
Researchers have called for the need to investigate the salesperson's role in customer value creation in the context of companies moving into service and solution businesses. Despite the indisputable importance of the sales function in the company's customer relationships and in value creation for these customers, relevant literature has not yet answered the question of what salespeople actually d
Primary health care resources for rehabilitation and secondary prevention after myocardial infarction - a questionnaire survey Background: During the first year after a cardiac event, many patients are offered participation in a cardiac rehabilitation programme, after which the patients are often not given the opportunity to continue to attend rehabilitation and secondary prevention programmes. Ai
Cathepsin B is suggested to be involved in amyloid-beta (A beta) processing and Alzheimer's disease (AD). Studies of cathepsin B levels in plasma and cerebrospinal fluid (CSF) have not been previously performed. We examined cathepsin B levels in plasma and CSF samples in persons with AD, mild cognitive impairment (MCI), and healthy controls in order to test the hypothesis that cathepsin B levels c
The S100 alarmins A8, A9, and A8/A9, secreted by activated neutrophils and monocytes/macrophages, are involved in the pathogenesis of various inflammatory diseases. S100A8/A9 has previously been linked to atherogenesis and cardiovascular (CV) disease. We investigated whether S100A8, A9, and A8/A9 correlate with carotid artery disease and CV risk in apparently healthy individuals.
An experimental study was conducted to investigate pressure drop and heat transfer in a U-bend section with various configurations of guide vanes and two kinds of rib shapes on the outer wall. Ten guide vane types were tested. Results highlight that the use of special guide vanes can reduce the pressure drop penalty up to a maximum of 31%. However, guide vanes are usually associated with heat tran
A search for the weak production of charginos and neutralinos decaying to a final state with three leptons (electrons or muons) and missing transverse momentum is presented. The analysis uses 2.06 fb(-1) of root s = 7 TeV proton-proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with standard model expectations in two sign
Objective Although Parkinson's disease is a common disorder in the elderly, there have been very few studies of the role of the pharmaceutical care services in detecting and reducing problems associated with drug treatment in community settings. The aim of this study was therefore to investigate the type and frequency of drug-related problems identified in patients with Parkinson's disease by comm
A new third polymorph of copper(II) decanoate has been found by two methods: from the crystallization of the saltacid solution and from a specific thermal treatment of the polymorph obtained in n-heptane. The new polymorph, whose crystal structure has been solved for the first time, is the most stable from the thermodynamic point of view. It presents a bilayer structure, but with two different typ
Abstract in Undetermined Recent research has shown that the pupil signal from video-based eye trackers contains post saccadic oscillations (PSOs). These reflect pupil motion relative to the limbus (Nyström, Hooge, & Holmqvist, 2013). More knowledge about video-based eye tracker signals is essential to allow comparison between the findings obtained from modern systems, and those of older eye tr
From an interplay between scanning tunneling microscopy, temperature programmed desorption, X-ray photoelectron spectroscopy, and density functional theory calculations we have studied low-temperature CO oxidation on Au/Ni(111) surface alloys and on Ni(111). We show that an oxide is formed on both the Ni(111) and the Au/Ni(111) surfaces when oxygen is dosed at 100 K, and that CO can be oxidized at
