Ipsilateral breast tumor recurrence (IBTR) is a clinically important event, where an isolated in-breast recurrence is a potentially curable event but associated with an increased risk of distant metastasis and breast cancer death. It remains unclear if IBTRs are associated with molecular changes that can be explored as a resource for precision medicine strategies. Here, we employed proteogenomics

Neutrons are widely used as probes of matter to study materials in a broad range of fields from physics, chemistry and medicine to material sciences. Any application utilizing neutrons needs to employ a well-understood and optimized neutron-detector system. This thesis is centered on fundamental aspects of neutron-detector development, including the establishment of the Source Testing Facility at

Context. The current architecture of a given multi-planetary system is a key fingerprint of its past formation and dynamical evolution history. Long-term follow-up observations are key to complete their picture. Aims. In this paper, we focus on the confirmation and characterization of the components of the TOI-969 planetary system, where TESS detected a Neptune-size planet candidate in a very clos

Background: Chronological age is a key clinical determinant ofaortic stiffness. Self-perceived age (SPA) is a strong predictor ofwell-being and long-term health. We aimed to investigate theassociation between SPA, chronological age, and aortic stiffness(vascular ageing) in the general population.Methods: Cross-sectional analysis of a population-based study,Malmö Offspring Study (n=3563). Mean age

Aim As part of its strategic objectives for 2023, EULAR aims to improve the work participation of people with rheumatic and musculoskeletal diseases (RMDs). One strategic initiative focused on the development of overarching points to consider (PtC) to support people with RMDs in healthy and sustainable paid work participation. Methods EULAR's standardised operating procedures were followed. A stee

Objectives To update the Assessment of SpondyloArthritis international Society (ASAS)-EULAR recommendations for the management of axial spondyloarthritis (axSpA). Methods Following the EULAR Standardised Operating Procedures, two systematic literature reviews were conducted on non-pharmacological and pharmacological treatment of axSpA. In a task force meeting, the evidence was presented, discussed

Objectives: To develop EULAR recommendations for screening and prophylaxis of chronic and opportunistic infections in patients with autoimmune inflammatory rheumatic diseases (AIIRD). Methods: An international Task Force (TF) (22 members/15 countries) formulated recommendations, supported by systematic literature review findings. Level of evidence and grade of recommendation were assigned for each

Objectives Evaluate the natural course of anterior cruciate ligament (ACL) healing on MRI within 5 years of acute ACL rupture and compare 2-year and 5-year outcomes based on healing status and treatment group. Methods Secondary analysis of 120 Knee Anterior Cruciate Ligament Nonsurgical vs Surgical Treatment (KANON) trial participants randomised to rehabilitation and optional delayed ACL reconstru

Background: The Nordic Nutrition Recommendations (NNR) are developed to promote public health and to prevent food-related diseases such as obesity and cardiovascular diseases. Objective: To investigate the nutrient intake and adherence to the NNR in a Swedish cohort with abdominal obesity. Design: Dietary intake data were collected using 3-day food diaries and anthropometry and clinical chemistry

This study examines business model innovation in an established firm. We investigate the case of a Swedish utility company that adopted and implemented a business model pattern originating from outside the firm. We draw upon Scandinavian translation theory to understand the micro-level dynamics of how business model innovation unfolds. Our findings show that the business model pattern is disassemb

This article is a response to Bill Gardner and Kelly McCauley’s ‘gaslighting’ critique of our text on the perils of authentic leadership. Against gaslighting 1.0 (evilly trying to convince people to doubt their perceptions), we propose gaslighting 2.0 (enlightenment). We argue that organizations face severe problems and challenges that cannot be solved by motivating managers to engage in introspec

In this study, the stabilization process is introduced to a clayey expansive soil collected in southern Sweden. The tests examined strength parameters of expansive soil stabilized by different binders using combination of both traditional binders (cement and lime) and alternative materials (slag Merit 5000, fly ash from SCA Lilla Edet and fly ash from coal combustion, ISO certified). The practical

Human-induced salinization increasingly threatens inland waters; yet we know little about the multifaceted response of lake communities to salt contamination. By conducting a coordinated mesocosm experiment of lake salinization across 16 sites in North America and Europe, we quantified the response of zooplankton abundance and (taxonomic and functional) community structure to a broad gradient of e

Sex differences in ecologically important traits are common in animals and plants, and prompted Darwin to first propose an ecological cause of sexual dimorphism. Despite theoretical plausibility and Darwin's original notion, a role for ecological resource competition in the evolution of sexual dimorphism has never been directly demonstrated and remains controversial. I used experimental evolution

Discourse analysis and discourse theories have become an established way for analyzing the social construction of foreign policy. Despite being a broad tent of approaches, all types of discourse analysis share a common interest in revealing the political ideas, linguistic practices, and social relations that constitute foreign policies from a bottom-up perspective. Having a sophisticated concept o